Joanna Bridger

Dr Joanna Bridger

Reader / Senior Tutor - Biosciences

Room: Heinz Wolff Building 132
Brunel University London
United Kingdom
Tel: +44 (0)1895 266272


Teaching responsibilities

  • Cellular Pathologies (Level 3)
  • Professional Skills (Level 2)
  • Final Year Projects (Level 3)
  • Masters dissertations (M-level)

Teaching / Supervision

Other responsibilities

Module coordinator

  • Genetics and Development (Level 2)
  • Clinical Cytogenetics (M-level)
  • Clinical Cytogenetics and Cancer




Journal Papers

(2014) Arican-Goktas, HD., Ittiprasert, W., Bridger, JM. and Knight, M., Differential spatial repositioning of activated genes in Biomphalaria glabrata snails infected with Schistosoma mansoni, PLoS Neglected Tropical Diseases 8 (9) : e3013- Download publication

(2014) Knight, M., Arican-Goktas, HD., Ittiprasert, W., Odoemelam, EC., Miller, AN. and Bridger, JM., Schistosomes and snails: A molecular encounter, Frontiers in Genetics 5230 Download publication

(2014) Bridger, JM., Arican-Gotkas, HD., Foster, HA., Godwin, LS., Harvey, A., Kill, IR., Knight, M., Mehta, IS. and Ahmed, MH., The non-random repositioning of whole chromosomes and individual gene loci in interphase nuclei and its relevance in disease, infection, aging, and cancer., Adv Exp Med Biol 773 263- 279 Download publication

(2013) Foster, HA., Estrada-Girona, G., Themis, M., Garimberti, E., Hill, MA., Bridger, JM. and Anderson, RM., Relative proximity of chromosome territories influences chromosome exchange partners in radiation-induced chromosome rearrangements in primary human bronchial epithelial cells, Mutation Research - Genetic Toxicology and Environmental Mutagenesis 756 (1-2) : 66- 77 Download publication

(2013) Wazir, U., Sharma, AK., Mokbel, K., Ahmed, MH., Bridger, JM., Harvey, A. and Jiang, WG., The clinicopathological significance of lamin A/C, lamin B1 and lamin B receptor mRNA expression in human breast cancer, Cellular and Molecular Biology Letters 1- 17

(2012) Adema, CM., Bayne, CJ., Bridger, JM., Knight, M., Loker, ES., Yoshino, TP. and Zhang, S-M., Will all scientists working on snails and the diseases they transmit please stand up?, PLoS Neglected Tropical Diseases 6 (12) : - Download publication

(2012) Foster, HA., Griffin, DK. and Bridger, JM., Interphase chromosome positioning in in vitro porcine cells and ex vivo porcine tissues, BMC Cell Biology 1330 Download publication

(2011) Bridger, JM., Chromobility: the rapid movement of chromosomes in interphase nuclei., Biochem Soc Trans 39 (6) : 1747- 1751 Download publication

(2011) Bridger, JM., Eskiw, CH., Makarov, EM., Tree, D. and Kill, IR., Progeria Research Day at Brunel University, Nucleus 2 (6) : 1- 6

(2011) Mehta, IS., Arican, HD., Eskiw, CH., Kill, IR. and Bridger, JM., Farnesyltransferase inhibitor treatment restores chromosome territory positions and active chromosome dynamics in Hutchinson-Gilford Progeria syndrome cells., Genome Biology: biology for the post-genomic era 12 (8) : R74 Download publication

(2011) Knight, M., Ittiprasert, W., Odoemelam, EC., Adema, CM., Miller, A., Raghavan, N. and Bridger, JM., Non-random organization of the Biomphalaria glabrata genome in interphase Bge cells and the spatial repositioning of activated genes in cells co-cultured with Schistosoma mansoni, International Journal for Parasitology 41 (1) : 61- 70

(2010) Szczerbal, I. and Bridger, JM., Association of adipogenic genes with SC-35 domains during porcine adipogenesis, Chromosome Research: the international journal for all aspects of chromosome and nuclear biology 18 (8) : 887- 895 Download publication

(2010) Stimpson, KM., Song, IY., Jauch, A., Holtgreve-Grez, H., Hayden, KE., Bridger, JM. and Sullivan, BA., Telomere disruption results in non-random formation of De Novo dicentric chromosomes involving acrocentric human chromosomes, PLOS Genetics 6 (8) : e1001061 Download publication

(2010) Elcock, LS. and Bridger, JM., Exploring the relationship between interphase gene positioning, transcriptional regulation and the nuclear matrix., Biochem Soc Trans 38 (Pt 1) : 263- 267 Download publication

(2010) Mehta, IS., Bridger, JM. and Kill, IR., Progeria, the nucleolus and farnesyltransferase inhibitors., Biochem Soc Trans 38 (Pt 1) : 287- 291 Download publication

(2010) Mehta, IS., Amira, M., Harvey, AJ. and Bridger, JM., Rapid chromosome territory relocation by nuclear motor activity in response to serum removal in primary human fibroblasts, Genome Biology 11 (1) : R5 Download publication

(2009) Odoemelam, E., Raghavan, N., Miller, A., Bridger, JM. and Knight, M., Revised karyotyping and gene mapping of the Biomphalaria glabrata embryonic (Bge) cell line, International Journal for Parasitology 39 (6) : 675- 681 Download publication

(2009) Szczerbal, I., Foster, HA. and Bridger, JM., The spatial repositioning of adipogenesis genes is correlated with their expression status in a porcine mesenchymal stem cell adipogenesis model system, Chromosoma: biology of the nucleus 118 (5) : 647- 663

(2008) Szczerbal, I., Foster, HA. and Bridger, JM., Changes in gene position in interphase during porcine adipogenesis are correlated with changes in gene expression (Abstract), Chromosome Research 16 (7) : 1033- 1034

(2008) Elcock, LS. and Bridger, JM., Exploring the effects of a dysfunctional nuclear matrix, Biochemical Society Transactions 36 (Part 6) : 1378- 1383

(2008) Volpi, EV. and Bridger, JM., FISH glossary: an overview of the fluorescence in situ hybridization technique, BioTechniques 45 (4) : 385- 409

(2008) Mehta, IS., Elcock, LS., Amira, M., Kill, IR. and Bridger, JM., Nuclear motors and nuclear structures containing A-type lamins and emerin: is there a functional link?, Biochemical Society Transactions 36 (Part 6) : 1384- 1388

(2008) Meaburn, KJ., Newbold, RF. and Bridger, JM., Positioning of human chromosomes in murine cell hybrids according to synteny, Chromosoma 117 (6) : 579- 591 Download publication

(2008) Beard, GS., Bridger, JM., Kill, IR. and Tree, DR., Towards a Drosophila model of Hutchinson-Gilford progeria syndrome, Biochemical Society Transactions 36 (Part 6) : 1389- 1392

(2007) Mehta, IS., Figgitt, M., Clements, CS., Kill, IR. and Bridger, JM., Alterations to nuclear architecture and genome behavior in senescent cells, Annals of the New York Academy of Sciences 1100 (Biogerontology Mechanisms and Interventions) : 250- 263

(2007) Foster, HA., Stokes, P., Forsey, K., Leese, HJ. and Bridger, JM., Lamins A and C are present in the nuclei of early porcine embryos, with lamin A being distributed in large intranuclear foci, Chromosome Research 15 (2) : 163- 174

(2007) Meaburn, KJ., Cabuy, E., Bonne, G., Levy, N., Morris, GE., Novelli, G., Kill, IR. and Bridger, JM., Primary laminopathy fibroblasts display altered genome organization and apoptosis, Aging Cell 6 (2) : 139- 153

(2007) Bridger, JM., Foeger, N., Kill, IR. and Herrmann, H., The nuclear lamina. Both a structural framework and a platform for genome organization, FEBS Journal 274 (6) : 1354- 1361

(2005) Meaburn, KJ., Levy, N., Toniolo, D. and Bridger, JM., Chromosome positioning is largely unaffected in lymphoblastoid cell lines containing emerin or A-type lamin mutations, Biochemical Society Transactions 33 (Part 6) : 1438- 1440 Download publication

(2005) Foster, HA., Abeydeera, LR., Griffin, DK. and Bridger, JM., Non-random chromosome positioning in mammalian sperm nuclei, with migration of the sex chromosomes during late spermatogenesis, Journal of Cell Science 118 (9) : 1811- 1820 Download publication

(2005) Foster, HA. and Bridger, JM., The genome and the nucleus: A marriage made by evolution - Genome organisation and nuclear architecture, Chromosoma 114 (4) : 212- 229

(2005) Meaburn, KJ., Parris, CN. and Bridger, JM., The manipulation of chromosomes by mankind: The uses of microcell-mediated chromosome transfer, Chromosoma 114 (4) : 263- 274

(2004) Bridger, JM. and Kill, IR., Aging of Hutchinson-Gilford progeria syndrome fibroblasts is characterised by hyperproliferation and increased apoptosis, Experimental Gerontology 39 (5) : 717- 724 Download publication

(2004) Bridger, JM., Mammalian artificial chromosomes: modern day feats of engineering - Isambard Kingdom Brunel style, Cytogenetic and Genome Research 107 (1-2) : 5- 8

(2001) Vaughan, OA., Alvarez-Reyes, M., Bridger, JM., Broers, JLV., Ramaekers, FCS., Wehnert, M., Morris, GE., Whitfield, WGF. and Hutchinson, CJ., Both emerin and lamin C depend on lamin A for localization at the nuclear envelope, Journal of Cell Science 114 (14) : 2577- 2590 Download publication

(2001) Sullivan, GJ., Bridger, JM., Cuthbert, AP., Newbold, RF., Bickmore, WA. and McStay, B., Human acrocentric chromosomes with transcriptionally silent nucleolar organiser regions associate with nucleoli, European Molecular Biology Organization 20 (11) : 2867- 2877 Download publication

(2001) Boyle, S., Gilchrist, S., Bridger, JM., Mahy, NL., Ellis, JA. and Bickmore, WA., The spatial organization of human chromosomes within the nuclei of normal and emerin-mutant cells, Human Molecular Genetics 10 (3) : 211- 219 Download publication

(2000) Bridger, JM., Boyle, S., Kill, IR. and Bickmore, WA., Re-modelling of nuclear architecture in quiescent and senescent human fibroblasts, Current Biology 10 (3) : 149- 152

(1999) Bickmore, WA. and Bridger, JM., A sense of time and place: Meeting report of HUGO spatial organisation of the genome workshop, Edinburgh, 14-15 May 1999, Chromosome Research 7 (6) : 425- 429

(1999) Croft, JA., Bridger, JM., Boyle, S., Perry, P., Teague, P. and Bickmore, WA., Differences in the localization and morphology of chromosomes in the human nucleus, Journal of Cell Biology 145 (6) : 1119- 1131 Download publication

(1998) Bridger, JM., Kill, IR. and Lichter, P., Association of pKi-67 with satellite DNA of the human genome in early G(1) cells, Chromosome Research 6 (1) : 13- 24

(1998) Bridger, JM. and Bickmore, WA., Putting the genome on the map, Trends in Genetics 14 (10) : 403- 409 Download publication

(1998) King, JA., Bridger, JM., Gounari, F., Lichter, P., Schulz, TF., Schirrmacher, V. and Khazaie, K., The extended packaging sequence of MoMLV contains a constitutive mRNA nuclear export function, FEBS Letters 434 (3) : 367- 371

(1994) Hutchison, CJ., Bridger, JM., Cox, LS. and Kill, IR., Weaving a pattern from disparate threads: lamin function in nuclear assembly and DNA replication, Journal of Cell Science 107 (12) : 3259- 3269 Download publication

(1993) Bridger, JM., Kill, IR., O'Farrell, M. and Hutchison, CJ., Internal lamin structures within G1 nuclei of human dermal fibroblasts, Journal of Cell Science 104 (2) : 297- 306 Download publication

(1991) Kill, IR., Bridger, JM., Campbell, KH., Maldonado-Codina, G. and Hutchison, CJ., The timing of the formation and usage of replicase clusters in S-phase nuclei of human diploid fibroblasts, Journal of Cell Science 100 (4) : 869- 876 Download publication

Book Chapters

(2010) Odoemelam, EC., Raghavan, N., Ittiprasert, W., Miller, A., Bridger, JM. and Knight, M., FISH on chromosomes derived from the snail model organism biomphalaria glabrata. In: Bridger, JM. and Volpi, EV. eds. Fluorescence in situ hybridization (FISH). Springer (659)

(2007) Knight, M., Bridger, JM., Ittiprasert, W., Odoemelam, E., Masabanda, J., Miller, A. and Raghavan, N., Mobile genetic elements in metazoan parasites. In: Brindley, PJ. ed. Mobile genetic elements in metazoan parasites. Landes Bioscience - Download publication


(2010) Bridger, JM. and Volpi, EV., Fluorescence in situ hybridization (FISH). Springer

Page last updated: Tuesday 25 November 2014