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Dr Evgeny Makarov
Senior Lecturer

Ragusa, D., Makarov, E., Britten, O., Moralli, D., Green, C. and Tosi, S. (2019) 'The RS4;11 cell line as a model for leukaemia with t(4;11)(q21;q23): revised characterisation of cytogenetic features'. Cancer Reports, 2019 (2). pp. 1 - 1. ISSN: 2573-8348 Open Access Link

Journal article

Clements, CS., Bikkul, MU., Ofosu, W., Eskiw, C., Tree, D., Makarov, E., et al. (2019) 'Presence and distribution of progerin in HGPS cells is ameliorated by drugs that impact on the mevalonate and mTOR pathways'. Biogerontology, 20 (3). pp. 337 - 358. ISSN: 1389-5729 Open Access Link

Journal article

Al-Qahtani, A., Murugaiah, V., Bashir, H., Pathan, AA., Abozaid, S., Makarov, E., et al. (2019) 'Full-length human Surfactant Protein A inhibits Influenza A Virus infection of A549 lung epithelial cells: a recombinant form containing neck and lectin domains promotes infectivity'. Immunobiology, 224 (3). pp. 408 - 418. ISSN: 0171-2985 Open Access Link

Journal article

Mehmet, B., Faragher, R., Worthington, G., Meinke, P., Kerr, A., Sammy, A., et al. (2018) 'Telomere elongation through hTERT immortalization leads to chromosome repositioning in control cells and genomic instability in Hutchinson-Gilford progeria syndrome fibroblasts, expressing a novel SUN1 isoform'. Genes, Chromosomes and Cancer, 58 (6). pp. 341 - 356. ISSN: 1045-2257 Open Access Link

Journal article

Al-Mozaini, M., Tsolaki, AG., Abdul-Aziz, M., Abozaid, SM., Al-Ahdal, MN., Pathan, AA., et al. (2018) 'Human properdin modulates macrophage: Mycobacterium bovis BCG interaction via thrombospondin repeats (TSR) 4 and 5'. Frontiers in Immunology, 9 (MAY). pp. 533. ISSN: 1664-3224 Open Access Link

Journal article

Burdakov, VS., Kovalev, RA., Pantina, RA., Varfolomeeva, EY., Makarov, EM. and Filatov, MV. (2018) 'Exosomes Transfer p53 between Cells and Can Suppress Growth and Proliferation of p53-Negative Cells'. Cell and Tissue Biology, 12 (1). pp. 20 - 26. ISSN: 1990-519X Open Access Link

Journal article

Makarov, E., Shtam, TA., Kovalev, RA., Pantina, RA., Varfolomeeva, EY. and Filatov, MV. (2017) 'The rare nonsense mutation in p53 triggers alternative splicing to produce a protein capable of inducing apoptosis'. PLoS ONE, 12 (9). pp. 1 - 14. ISSN: 1932-6203 Open Access Link

Journal article

Makarov, E. and Makarova, O. (2015) 'The 35S U5 snRNP Is Generated from the Activated Spliceosome during In vitro Splicing.'. PLoS One, 10 (5). pp. e0128430 - e0128430. ISSN: 1932-6203 Open Access Link

Journal article

Kovalev, RA., Shtam, TA., Karelov, DV., Burdakov, VS., Volnitskiy, AV., Makarov, EM. and et al. (2015) 'Histone deacetylase inhibitors cause TP53-dependent induction of p21/Waf1 in tumor cells with TP53 mutations'. Cell and Tissue Biology, 9 (3). pp. 191 - 197. ISSN: 1990-519X Open Access Link

Journal article

Shtam, TA., Kovalev, RA., Varfolomeeva, EY., Makarov, EM., Kil, YV. and Filatov, MV. (2013) 'Exosomes are natural carriers of exogenous siRNA to human cells in vitro'. Cell Communication and Signaling, 11 (1). pp. 1 - 10. ISSN: 1478-811X Open Access Link

Journal article

Girard, C., Will, CL., Peng, J., Makarov, EM., Kastner, B., Lemm, I., et al. (2012) 'Post-transcriptional spliceosomes are retained in nuclear speckles until splicing completion.'. Nature Communications, 3 (1). pp. 994. ISSN: 2041-1723

Journal article

Makarov, EM., Owen, N., Bottrill, A. and Makarova, OV. (2012) 'Functional mammalian spliceosomal complex E contains SMN complex proteins in addition to U1 and U2 snRNPs'. Nucleic Acids Research, 40 (6). pp. 2639 - 2652. ISSN: 0305-1048 Open Access Link

Journal article

Bridger, JM., Eskiw, CH., Makarov, EM., Tree, D. and Kill, IR. (2011) 'Progeria Research Day at Brunel University'. Nucleus, 2 (6). pp. 1 - 6. ISSN: 1949-1034

Journal article

Abbaszadeh, F., Clingen, PH., Arlett, C., Plowman, PN., Bourton, EC., Themis, M., et al. (2010) 'A novel splice variant of the DNA-PKcs gene is associated with clinical and cellular radiosensitvity in a xeroderma pigmentosum patient'. Journal of Medical Genetics, 46 (11). pp. 1 - 24. ISSN: 0022-2593 Open Access Link

Journal article

Bujakowska, K., Maubaret, C., Chakarova, CF., Tanimoto, N., Beck, SC., Fahl, E., et al. (2009) 'Study of gene-targeted mouse models of splicing factor gene Prpf31 implicated in human autosomal dominant retinitis pigmentosa (RP)'. Investigative Ophthalmology and Visual Science, 50 (12). pp. 5927 - 5933. ISSN: 0146-0404

Journal article

Hernández, H., Makarova, OV., Makarov, EM., Morgner, N., Muto, Y., Krummel, DP. and et al. (2009) 'Isoforms of U1-70k control subunit dynamics in the human spliceosomal U1 snRNP'. PLoS ONE, 4 (9). pp. e7202 - e7202. ISSN: 1932-6203 Open Access Link

Journal article

Sander, B., Golas, MM., Makarov, EM., Brahms, H., Kastner, B., Lührmann, R. and et al. (2006) 'Organization of core spliceosomal components U5 snRNA loop I and U4/U6 di-snRNP within U4/U6.U5 tri-snRNP as revealed by electron cryomicroscopy'. Molecular Cell, 24 (2). pp. 267 - 278. ISSN: 1097-2765

Journal article

Laggerbauer, B., Liu, S., Makarov, E., Vornlocher, HP., Makarova, O., Ingelfinger, D., et al. (2005) 'The human U5 snRNP 52K protein (CD2BP2) interacts with U5-102K (hPrp6), a U4/U6.U5 tri-snRNP bridging protein, but dissociates upon tri-snRNP formation'. RNA, 11 (5). pp. 598 - 608. ISSN: 1355-8382

Journal article

Makarova, OV., Makarov, EM., Urlaub, H., Will, CL., Gentzel, M., Wilm, M. and et al. (2004) 'A subset of human 35S U5 proteins, including Prp19, function prior to catalytic step 1 of splicing'. The EMBO Journal, 23 (12). pp. 2381 - 2391. ISSN: 0261-4189

Journal article

Boehringer, D., Makarov, EM., Sander, B., Makarova, OV., Kastner, B., Lührmann, R. and et al. (2004) 'Three-dimensional structure of a pre-catalytic human spliceosomal complex B'. Nature Structural & Molecular Biology, 11 (5). pp. 463 - 468. ISSN: 1545-9993

Journal article

Makarov, EM., Makarova, OV., Urlaub, H., Gentzel, M., Will, CL., Wilm, M. and et al. (2002) 'Small nuclear ribonucleoprotein remodeling during catalytic activation of the spliceosome'. Science, 298 (5601). pp. 2205 - 2208. ISSN: 0036-8075

Journal article

Dellaire, G., Makarov, EM., Cowger, JJ., Longman, D., Sutherland, HG., Lührmann, R., et al. (2002) 'Mammalian PRP4 kinase copurifies and interacts with components of both the U5 snRNP and the N-CoR deacetylase complexes'. Mol Cell Biol, 22 (14). pp. 5141 - 5156. ISSN: 0270-7306

Journal article

Schneider, C., Will, CL., Makarova, OV., Makarov, EM. and Lührmann, R. (2002) 'Human U4/U6.U5 and U4atac/U6atac.U5 tri-snRNPs exhibit similar protein compositions'. Molecular and Cellular Biology, 22 (10). pp. 3219 - 3229. ISSN: 0270-7306

Journal article

Makarova, OV. (2001) 'The 65 and 110 kDa SR-related proteins of the U4/U6U5 tri-snRNP are essential for the assembly of mature spliceosomes'. The EMBO Journal, 20 (10). pp. 2553 - 2563. ISSN: 0261-4189

Journal article

Makarov, EM., Makarova, OV., Achsel, T. and Lührmann, R. (2000) 'The human homologue of the yeast splicing factor Prp6p contains multiple TPR elements and is stably associated with the U5 snRNP via protein-protein interactions.'. J Mol Biol, 298 (4). pp. 567 - 575. ISSN: 0022-2836

Journal article

Venables, JP. (2000) 'RBMY, a probable human spermatogenesis factor, and other hnRNP G proteins interact with Tra2beta and affect splicing'. Human Molecular Genetics, 9 (5). pp. 685 - 694. ISSN: 0964-6906

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Elliott, DJ., Oghene, K., Makarov, G., Makarova, O., Hargreave, TB., Chandley, AC., et al. (1998) 'Dynamic changes in the subnuclear organisation of pre-mRNA splicing proteins and RBM during human germ cell development'. Journal of Cell Science, 111 (9). pp. 1255 - 1265. ISSN: 0021-9533

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Makarova, OV., Makarov, EM., Sousa, R. and Dreyfus, M. (1995) 'Transcribing of Escherichia coli genes with mutant T7 RNA polymerases: stability of lacZ mRNA inversely correlates with polymerase speed.'. Proceedings of the National Academy of Sciences, 92 (26). pp. 12250 - 12254. ISSN: 0027-8424

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