Skip to Content
Exit Menu
Dr Luigi Margiotta-Casaluci

Dr Luigi Margiotta-Casaluci
Research Fellow

Summary

I am a Research Fellow in Toxicology and Group Leader at the Institute of Environment, Health and Societies. My research focuses on understanding the multi-scale effects of pharmaceuticals, alone and in combination, and developing predictive models able to inform drug safety assessment for both humans and wildlife. 

Career

2015-to date: Group Leader & Research Fellow, Translational Pharmacology & Toxicology, Insitute of Environment, Health and Socities/College of Life Sciences, Brunel University London, UK

2011-2013: Visiting Scientist, AstraZeneca, UK

2011-2015: Post-doctoral Research Fellow, AstraZenenca/Brunel University London, London, UK (funded by BBSRC/AstraZeneca).

Education

2007–2011: Ph.D. in Environmental Toxicology, Brunel University, London, UK (supported by GlaxoSmithKline).               Integrated testing strategy for the study of the effects of the human pharmaceutical dutasteride on fish.

2003-2005: MSc Marine Biology, Universita’ Politecnica delle Marche, Ancona, Italy.

2000-2003: BSc Biological Sciences, Universita’ Politecnica delle Marche, Ancona, Italy.

Newest selected publications

Knapen, D., Angrish, MM., Fortin, MC., Katsiadaki, I., Leonard, M., Margiotta-Casaluci, L., et al. (2018) 'Adverse outcome pathway networks I: Development and applications.'. Environ Toxicol Chem, 37 (6). pp. 1723 - 1733. ISSN: 0730-7268 Open Access Link

Journal article

Villeneuve, DL., Angrish, MM., Fortin, MC., Katsiadaki, I., Leonard, M., Margiotta-Casaluci, L., et al. (2018) 'Adverse outcome pathway networks II: Network analytics.'. Environ Toxicol Chem, 37 (6). pp. 1734 - 1748. ISSN: 0730-7268 Open Access Link

Journal article

Tanoue, R., Margiotta-Casaluci, L., Huerta, B., Runnalls, TJ., Nomiyama, K., Kunisue, T., et al. (2017) 'Uptake and Metabolism of Human Pharmaceuticals by Fish: A Case Study with the Opioid Analgesic Tramadol.'. Environ Sci Technol, 51 (21). pp. 12825 - 12835. ISSN: 0013-936X Open Access Link

Journal article

Huerta, B., Margiotta-Casaluci, L., Rodríguez-Mozaz, S., Scholze, M., Winter, MJ., Barceló, D. and et al. (2016) 'Anti-anxiety drugs and fish behavior: Establishing the link between internal concentrations of oxazepam and behavioral effects.'. Environ Toxicol Chem, 35 (11). pp. 2782 - 2790. ISSN: 0730-7268 Open Access Link

Journal article

Margiotta-Casaluci, L., Owen, SF., Huerta, B., Rodríguez-Mozaz, S., Kugathas, S., Barceló, D., et al. (2016) 'Internal exposure dynamics drive the Adverse Outcome Pathways of synthetic glucocorticoids in fish.'. Sci Rep, 6 (1). pp. 21978. ISSN: 2045-2322 Open Access Link

Journal article
More publications(16)