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Dr Thomas Hofken
Senior Lecturer

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Joshua, I., Lin, M., Mardjuki, A., Mazzola, A. and Hoefken, T. (2023) 'A protein-protein interaction analysis suggests a wide range of new functions for the p21-activated kinase (PAK) Ste20'. International Journal of Molecular Sciences, 24 (21). pp. 1 - 31. ISSN: 1661-6596 Open Access Link

Journal article

Hoefken, T. and Joshua, I. (2019) 'Ste20 and Cla4 modulate the expression of the glycerol biosynthesis enzyme Gpd1 by a novel MAPK-independent pathway'. Biochemical and Biophysical Research Communications, 517 (4). pp. 611 - 616. ISSN: 0006-291X Open Access Link

Journal article

Hoefken, T. (2017) 'Ecm22 and Upc2 regulate yeast mating through control of expression of the mating genes PRM1 and PRM4'. Biochemical and Biophysical Research Communications, 493 (4). pp. 1485 - 1490. ISSN: 0006-291X Open Access Link

Journal article

Joshua, IM. and Hoefken, T. (2017) 'From lipid homeostasis to differentiation: Old and new functions of the zinc cluster proteins Ecm22, Upc2, Sut1 and Sut2'. International Journal of Molecular Sciences, 18 (4). pp. 1 - 17. ISSN: 1661-6596 Open Access Link

Journal article

Kennedy, H., Haack, TB., Hartill, V., Matakovic, L., Baumgartner, ER., Potter, H., et al. (2016) 'Sudden cardiac death due to deficiency of the mitochondrial inorganic pyrophosphatase PPA2'. The American journal of human genetics, 99 (3). pp. 674 - 682. ISSN: 0002-9297 Open Access Link

Journal article

Blanda, C. and Höfken, T. (2013) 'Regulation of mating in the budding yeast Saccharomyces cerevisiae by the zinc cluster proteins Sut1 and Sut2'. Biochemical and Biophysical Research Communications, 438 (1). pp. 66 - 70. ISSN: 0006-291X Open Access Link

Journal article

Foster, HA., Cui, M., Naveenathayalan, A., Unden, H., Schwanbeck, R. and Höfken, T. (2013) 'The zinc cluster protein Sut1 contributes to filamentation in Saccharomyces cerevisiae'. Eukaryot Cell, 12 (2). pp. 244 - 253. ISSN: 1535-9778 Open Access Link

Journal article

Blanda, C. and Höfken, T. (2013) 'Regulation of mating in the budding yeast Saccharomyces cerevisiae by the zinc cluster proteins Sut1 and Sut2'. Biochemical and Biophysical Research Communications. ISSN: 0006-291X

Journal article

Lin, M., Li, SC., Kane, PM. and Höfken, T. (2012) 'Regulation of vacuolar H -ATPase activity by the Cdc42 effector Ste20 in Saccharomyces cerevisiae'. Eukaryotic Cell, 11 (4). pp. 442 - 451. ISSN: 1535-9778 Open Access Link

Journal article

Hoefken, T. (2011) 'Candida and candidiasis', in Kishore, U. and Nayak, A. (eds.) Microbial pathogenesis: Infection and immunity. Springer Science+Business Media and Landes Bioscience. pp. 82 - 114. ISBN 13: 978-1-4614-9529-1.

Book chapter

Lin, M., Unden, H., Jacquier, N., Schneiter, R., Just, U. and Höfken, T. (2009) 'The Cdc42 effectors Ste20, Cla4, and Skm1 down-regulate the expression of genes involved in sterol uptake by a mitogen-activated protein kinase-independent pathway'. Molecular Biology of the Cell, 20 (22). pp. 4826 - 4837. ISSN: 1939-4586 Open Access Link

Journal article

Lin, M., Grillitsch, K., Daum, G., Just, U. and Höfken, T. (2009) 'Modulation of sterol homeostasis by the Cdc42p effectors Cla4p and Ste20p in yeast Saccharomyces cerevisiae'. FEBS Journal, 276 (24). pp. 7253 - 7264. ISSN: 1742-464X Open Access Link

Journal article

Tiedje, C., Sakwa, I., Just, U. and Höfken, T. (2008) 'The Rho GDI Rdi1 regulates Rho GTPases by distinct mechanisms'. Molecular Biology of the Cell, 19 (7). pp. 2885 - 2896. ISSN: 1939-4586 Open Access Link

Journal article

Tiedje, C., Holland, DG., Just, U. and Höfken, T. (2007) 'Proteins involved in sterol synthesis interact with Ste20 and regulate cell polarity'. Journal of Cell Science, 120 (20). pp. 3613 - 3624. ISSN: 0021-9533

Journal article

Höfken, T. and Schiebel, E. (2004) 'Novel regulation of mitotic exit by the Cdc42 effectors Gic1 and Gic2'. Journal of Cell Biology, 164 (2). pp. 219 - 231. ISSN: 0021-9525 Open Access Link

Journal article

Höfken, T. and Schiebel, E. (2002) 'A role for cell polarity proteins in mitotic exit'. EMBO Journal, 21 (18). pp. 4851 - 4862. ISSN: 0261-4189

Journal article

Weber, H., Wagner, ACC., Jonas, L., Merkord, J., Hõfken, T., Nizze, H., et al. (2000) 'Heat shock response is associated with protection against acute interstitial pancreatitis in rats'. Digestive Diseases and Sciences, 45 (11). pp. 2252 - 2264. ISSN: 0163-2116

Journal article

Höfken, T., Keller, N., Fleischer, F., Göke, B. and Wagner, ACC. (2000) 'Map kinase phosphatases (MKP's) are early responsive genes during induction of cerulein hyperstimulation pancreatitis'. Biochemical and Biophysical Research Communications, 276 (2). pp. 680 - 685. ISSN: 0006-291X

Journal article

Pereira, G., Höfken, T., Grindlay, J., Manson, C. and Schiebel, E. (2000) 'The Bub2p spindle checkpoint links nuclear migration with mitotic exit'. Molecular Cell, 6 (1). pp. 1 - 10. ISSN: 1097-2765

Journal article

Metzler, W., Höfken, T., Weber, H., Printz, H., Göke, B. and Wagner, ACC. (1999) 'Hyperthermia, inducing pancreatic heat-shock proteins, fails to prevent cerulein-induced stress kinase activation'. Pancreas, 19 (2). pp. 150 - 157. ISSN: 0885-3177

Journal article

Wagner, ACC., Metzler, W., Höfken, T., Weber, H. and Göke, B. (1999) 'p38 Map kinase is expressed in pancreas and is immediately activated following Cerulein hyperstimulation'. Digestion, 60 (1). pp. 41 - 47. ISSN: 0012-2823

Journal article

Höfken, T., Linder, D., Kleene, R., Göke, B. and Wagner, ACC. (1998) 'Membrane dipeptidase and glutathione are major components of pig pancreatic zymogen granules'. Experimental Cell Research, 244 (2). pp. 481 - 490. ISSN: 0014-4827

Journal article