Amanda Harvey

Academic qualifications

• PhD - Studies into the growth survival and cell death of cancer cell lines, University of Sheffield Medical School.
• BSc (Hons) Biochemistry - University of Wales, College of Cardiff

Professional development

• 2008: PGCert TLHE
• 2006: Enrolled PG Cert Brunel University
• 2001: College Certificate in Teaching Skills for Higher Education, Royal Holloway University of London  

Admin responsibilities

• Learning and Teaching Coordinator (Biosciences)
• School Coordinator for PGCert
• Academic Programme Review of Teaching
• Member of the PGCert Working Group
  

Teaching responsibilities

• BB3233 Pharmacology and Toxicology

• BB1202 Biochemistry: Structure and Function
• BB2269/2201 Professional Skills for Biochemists
• BB3217/3204 Biology, Genetics and Treatment of Cancer
• BB5503/5513 Genomic Technologies
• BB5504/5514 Cell Signalling

Academic appointments

• 2006: Lecturer in Biomedical Sciences, Division of Biosciences, School of Health Sciences and Social Care
• 2000-2006: Post-doctoral researcher, School of Biological Sciences, Royal Holloway University of London
• 1998-2000: Post-doctoral researcher, Human metabolism and Clinical Biochemistry, University of Sheffield Medical School
• 1997-1998: Research Assistant, Clinical Sciences Centre, University of Sheffield
• 1993-1997: Robert-Boulcher PhD scholarship, Institute for Cancer Studies, University of Sheffield Medical School

Research centres

• Brunel Institute for Cancer Genetics and Pharmacogenomics (BICGP)
• Centre for Cell and Chromosome Biology (CCCB)

Publications

Journal Papers

(2011) Tupper, J., Crompton, MR. and Harvey, AJ., Breast tumor kinase (Brk/PTK6) plays a role in the differentiation of primary keratinocytes, Archives of Dermatological Research 303 (4) : 293- 297 Download publication

(2010) Foster, H., Coley, HM., Goumenou, A., Pados, G., Harvey, A. and Karteris, E., Differential expression of mTOR signalling components in drug resistance in ovarian cancer, Anticancer Research 30 (9) : 3529- 3534 Download publication

(2010) Mparmpakas, D., Zachariades, E., Foster, H., Kara, A., Harvey, A., Goumenou, A. and Karteris, E., Expression of mTOR and downstream signalling components in the JEG-3 and BeWo human placental choriocarcinoma cell lines, International Journal of Molecular Medicine 25 (1) : 65- 69 Download publication

(2010) Mehta, IS., Amira, M., Harvey, AJ. and Bridger, JM., Rapid chromosome territory relocation by nuclear motor activity in response to serum removal in primary human fibroblasts, Genome Biology 11 (1) : R5 Download publication

(2009) Harvey, AJ., Pennington, CJ., Porter, S., Burmi, RS., Edwards, DR., Court, W., Eccles, SA. and Crompton, MR., Brk protects breast cancer cells from autophagic cell death induced by loss of anchorage, American Journal of Pathology 175 (3) : 1226- 1234 Download publication

(2006) Withey, JME., Harvey, AJ. and Crompton, MR., RNA interference targeting of Bcr-Abl increase chronic myeloid leukaemia cell killing by 17-allylamino-17-demethoxygeldanamycin., Leukaemia Research 30 (5) : 553- 560

(2006) Cross, NA., Reid, SV., Harvey, AJ., Jokonya, N. and Eaton, CL., Opposing actions of TGFβ1 and FGF2 on growth and differentiation of prostatic stromal cells: Implications for benign prostatic hyperplasia progression, Growth Factors 24 (4) : 233- 241

(2005) Withey, JME., Marley, S., Kaeda, J., Harvey, AJ., Crompton, M. and Gordon, MY., Targeting primary human leukaemia cells with RNA interference: Bcr-Abl targeting inhibits myeloid progenitor self-renewal in chronic myeloid leukaemia cells., British Journal of Haematology 129 (3) : 377- 380

(2004) Harvey, AJ. and Crompton, MR., The Brk protein tyrosine kinase as a therapeutic target in cancer: Opportunities and challenges, Anti-Cancer Drugs 15 (2) : 107- 111

(2003) Harvey, AJ. and Crompton, MR., Use of RNA interference to validate Brk as a novel therapeutic target in breast cancer: Brk promotes breast carcinoma cell proliferation, Oncogene 22 (32) : 5006- 5010

(2001) Bretland, AJ., Reid, SV., Chapple, CR. and Eaton, CL., Role of endogenous transforming growth factor β (TGFβ) 1 in prostatic stromal cells, The Prostate 48 (4) : 297- 304

(2001) Bretland, AJ., Lawry, J. and Sharrard, RM., A study of death by anoikis in cultured epithelial cells, Cell Proliferation 34 (4) : 199- 210

(1999) Klinger, HC., Bretland, AJ., Reid, SV., Chapple, CR. and Eaton, CL., Regulation of prostatic stromal cell growth and function by transforming growth factor beta (TGFβ), The Prostate 41 (2) : 110- 120

Book Chapters

(2011) Harvey, A. and Burmi, RS., Future therapeutic strategies: Implications for Brk targeting. In: Gunduz, E. and Gundez, M. eds. Breast Cancer - Current and Alternative Therapeutic Modalities. InTech Download publication