Mariann Rand-Weaver

Academic qualifications

• PhD Biochemistry 1986 - King’s College (KQC), London (awarded Tadion-Rideal Prize for distinguished post-graduate work)
• BSc Biochemistry 1982 - First Class Honours King’s College (KQC), London.

Committee responsibilities

• Chair, School of Learning and Teaching Committee (01/2010 - )
• Chair, School Postgraduate Programme Leaders' Committee (01/2010 - )
• Member, School Senior Management Group (09/2009 - )
• Member, University Learning and Teaching Committee (01/2010 - )
• Member, University Finance Committee (09/2008 - 07/2009)
• Project Manager for HW lab refurbishment (09/2007 - 10/2008)
• Chair, Academic Appeals Committee (01/2006 - 10/2008)
• Council Member (09/2004-07/2009)
• Senate Representative  (09/2002-10/2008)
• Disciplinary Panel member (09/2004-12/2005)
• Committee for Academic Staff Promotion (09/2004-8/2006); (09/2007-10/2008)
• Learning and Teaching Committee member (09/2003-08/2004) 

Admin responsibilities

• Deputy Head of School (Learning and Teaching) (1/2010 - )
• Director of Biosciences (8/2004 - 7/2008)
• Head of Department (5/2004-7/2004)
• Deputy Head of Department (9/2001-5/2004)
• Director of Undergraduate Studies (8/2001-5/2004)
• Chair, Board of Examiners (8/2001- 7/2008)
• Chair, Teaching Committee (8/2001-5/2004)
• Chair, Board of Studies (8/2001- 7/2004)
• Line Manager for Secretarial Staff (9/2001 - 07/2004)
• Senior Tutor (10/1997-7/2000; 2-5/2004)
• GM Safety Committee member (10/1994 - 07/2004) 

Teaching responsibilities

• Endocrine Disorders (This module is sponsored by the Society for Endocrinology in form of the Undergraduate Achievement Award, £300/yr)
• Metabolic Regulation
• Principles of Human Disease

PhD supervision

Students currently under supervision: 4

Research interests

I am currently involved in research council/industry-funded projects aimed at evaluating the mode of action of environmental chemicals and pharmaceuticals, and their impact on aquatic organisms. Studies at the genetic, protein and physiological levels are conducted. Building on my interest and expertise in endocrinology, I am developing a more health-related focus and have recently become involved in investigating the underlying mechanisms of drug resistance in hormone-dependent breast cancer, and the endocrine actions of phytoestrogens.

Research centres

• Brunel Institute for Cancer Genetics and Pharmacogenomics (BICGP)

Research projects and grants

• BBSRC Research Grant (PI: Prof JP Sumpter), April 2011 - March 2014
• BBSRC CASE Studentship, Oct 2010 - September 2011
  
• Hosting Commonwealth Fellow, October 2010 - March 2011  

Membership and affiliation

Society for Endocrinology

Professional activities or recognition

• Member of International Expert Panel for Norwegian Research Council (2007 - 2009)
• Editorial Board member for General and Comparative Endocrinology (1998-)
• Editorial Board member of Comparative Biochemistry and Physiology (2002-2003)
• Reviewer of abstract submissions to the Society of Endocrinology annual meeting
• Reviewer of grant applications for national (BBSRC, NERC) and international (Norwegian, US, Israeli) grant awarding bodies
• PhD External Examiner (UK, Norway)
• Reviewer of paper submissions to a wide range of journals

Publications

Journal Papers

(2011) Giltrow, E., Eccles, PD., Hutchinson, TH., Sumpter, JP. and Rand-Weaver, M., Characterisation and expression of β1-, β2- and β3-adrenergic receptors in the fathead minnow (Pimephales promelas), General and Comparative Endocrinology 173 (3) : 483- 490 Download publication

(2009) Giltrow, E., Eccles, PD., Winter, MJ., McCormack, PJ., Rand-Weaver, M., Hutchinson, TH. and Sumpter, JP., Chronic effects assessment and plasma concentrations of the β-blocker propranolol in fathead minnows (Pimephales promelas), Aquatic Toxicology 95 (3) : 195- 202 Download publication

(2007) Rand-Weaver, M., Bannister, R., Beresford, N., May, D. and Routledge, EJ., Novel estrogen receptor-related transcripts in Marisa cornuarietis: A freshwater snail with reported sensitivity to estrogenic chemicals, Environmental Science and Technology 41 (7) : 2643- 2650

(2003) Halm, S., Kwon, JY., Rand-Weaver, M., Sumpter, JP., Pounds, N., Hutchinson, TH. and Tyler, CR., Cloning and gene expression of P450 17α-hydroxylase, 17,20-lyase cDNA in the gonads and brain of the fathead minnow Pimephales promelas, General and Comparative Endocrinology 130 (3) : 256- 266

(2003) Pottinger, TG., Rand-Weaver, N. and Sumpter, JP., Overwinter fasting and re-feeding in rainbow trout: Plasma growth hormone and cortisol levels in relation to energy mobilisation, Comparative Biochemistry and Physiology Part B: Biochemistry and Molecular Biology 136 (3) : 403- 417

(2002) Halm, S., Pounds, N., Maddix, S., Rand-Weaver, M., Sumpter, JP., Hutchinson, TH. and Tyler, CR., Exposure to exogenous 17β-oestradiol disrupts P450aromB mRNA expression in the brain and gonad of adult fathead minnows (Pimephales promelas), Aquatic Toxicology 60 (3-4) : 285- 299

(2001) Halm, S., Rand-Weaver, M., Sumpter, JP. and Tyler, CR., Cloning and molecular characterization of an ovarian-derived (brain-like) P450 aromatase cDNA and development of a competitive RT-PCR assay to quantify its expression in the fathead minnow (pimephales promelas), Fish Physiology and Biochemistry 24 (1) : 49- 62