Professor Arturo Sala

Research centres

• Brunel Institute for Cancer Genetics and Pharmacogenomics (BICGP)

Publications

Journal Papers

(2013) Corvetta, D., Chayka, O., Gherardi, S., D'Acunto, CW., Cantilena, S., Valli, E., Piotrowska, I., Perini, G. and Sala, A., Physical Interaction between MYCN Oncogene and Polycomb Repressive Complex 2 (PRC2) in Neuroblastoma: FUNCTIONAL AND THERAPEUTIC IMPLICATIONS., J Biol Chem 288 (12) : 8332- 8341 Download publication

(2013) Santilli, G., Piotrowska, I., Cantilena, S., Chayka, O., D'Alicarnasso, M., Morgenstern, DA., Himoudi, N., Pearson, K., Anderson, J., Thrasher, AJ. and Sala, A., Polyphenol E enhances the antitumor immune response in neuroblastoma by inactivating myeloid suppressor cells., Clin Cancer Res 19 (5) : 1116- 1125 Download publication

(2012) Sottile, F., Gnemmi, I., Cantilena, S., D'Acunto, WC. and Sala, A., A chemical screen identifies the chemotherapeutic drug topotecan as a specific inhibitor of the B-MYB/MYCN axis in neuroblastoma, Oncotarget 3 (5) : 535- 545 Download publication

(2012) Sala, A., c-MYB and TGFβ: EMT's dynamic duo in breast cancer., Cell Cycle 11 (1) : 17- Download publication

(2011) Cantilena, S., Pastorino, F., Pezzolo, A., Chayka, O., Pistoia, V., Ponzoni, M. and Sala, A., Frizzled receptor 6 marks rare, highly tumourigenic stem-like cells in mouse and human neuroblastomas, Oncotarget 2 (12) : 976- 983 Download publication

(2011) Chaiwatanasirikul, KA. and Sala, A., The tumour-suppressive function of CLU is explained by its localisation and interaction with HSP60, Cell Death and Disease (2) : e219

(2010) Gualdrini, F., Corvetta, D., Cantilena, S., Chayka, O., Tanno, B., Raschellà, G. and Sala, A., Addiction of MYCN amplified tumours to B-MYB underscores a reciprocal regulatory loop, Oncotarget 1 (4) : 278- 288

(2009) Bettuzzi, S., Davalli, P., Davoli, S., Chayka, O., Rizzi, F., Belloni, L., Pellacani, D., Fregni, G., Astancolle, S., Fassan, M., Corti, A., Baffa, R. and Sala, A., Genetic inactivation of ApoJ/clusterin: Effects on prostate tumourigenesis and metastatic spread, Oncogene 28 (49) : 4344- 4352

(2009) Sala, A., Bettuzzi, S., Pucci, S., Chayka, O., Dews, M. and Thomas-Tikhonenko, A., Regulation of CLU gene expression by oncogenes and epigenetic factors implications for tumorigenesis, Advances in Cancer Research 105 (1) : 115- 132

(2009) Chayka, O., Corvetta, D., Dews, M., Caccamo, AE., Piotrowska, I., Santilli, G., Gibson, S., Sebire, NJ., Himoudi, N., Hogarty, MD., Anderson, J., Bettuzzi, S., Thomas-Tikhonenko, A. and Sala, A., Clusterin, a haploinsufficient tumor suppressor gene in neuroblastomas, Journal of the National Cancer Institute 101 (9) : 663- 677

(2008) Schwab, R., Bussolari, R., Corvetta, D., Chayka, O., Santilli, G., Kwok, JM., Ferrari-Amorotti, G., Tonini, GP., Iacoviello, L., Bertorelle, R., Menin, C., Hubank, M., Calabretta, B. and Sala, A., Isolation and functional assessment of common, polymorphic variants of the B-MYB proto-oncogene associated with a reduced cancer risk, Oncogene 27 (20) : 2929- 2933

(2007) Schwab, R., Caccamo, A., Bettuzzi, S., Anderson, J. and Sala, A., B-MYB is hypophosphorylated and resistant to degradation in neuroblastoma: Implications for cell survival, Blood Cells, Molecules, and Diseases 39 (3) : 263- 271

(2003) Santilli, G., Aronow, BJ. and Sala, A., Essential requirement of apolipoprotein J (clusterin) signaling for IkappaB expression and regulation of NF-kappaB activity, Journal of Biological Chemistry 278 (40) : 38214- 38219