Centre for Infection, Immunity and Disease Mechanisms (CIIDM)

The CIIDM carries out translational research relevant to human health and diseases, with the main aim of setting up clinical trials, and developing novel therapeutics and diagnostics. Our major research programmes include:

  1. Translational: Clinical trials involving surfactant protein D in asthma and infection; pre-clinical trials in Alzheimer’s disease, graft rejection and lupus nephritis.
  2. Host-pathogen interaction: Influenza A Virus, HIV-I, Mycobacterium tuberculosis, Neisseria meningitides, Aspergillus fumigates, Candida albicans, Pneumocystis, malaria parasite and Schistosome.
  3. Understanding disease mechanisms: asthma, tuberculosis, pregnancy-related disorders, thalassaemia, various disease models
  4. Immune deviations: Immunosenescence, autoimmunity and tumour immunology
  5. Neurology: role of complement in neurodegeneration; neurophysiology and rehabilitation; neuroimmunopsychology.

Research highlights

  • Host-pathogen interaction studies via comparative genomics, microarray, bioinformatics, biomarkers and host susceptibility factors; state-of-the-art pathogen research facilities
  • Innate immunity, therapeutics in asthma and lung infection
  • Biomarkers for diagnosis and treatment of tuberculosis; novel vaccination strategies against tuberculosis
  • Novel therapeutic intervention against Neiserria infection
  • Human Gene therapy in cancer and pulmonary diseases
  • Immunology of pregnancy and related complications: preeclampsia, preterm birth, and intrauterine growth retardation
  • Generation of complement inhibitors

Contact Details

For further information about the centre please contact Dr Uday Kishore, PhD (Director).

Email: uday.kishore@brunel.ac.uk
Tel: +44 (0)1895 266362 (Office), +44 (0)1895 265638 (Lab)

Uday Kishore

Centre for Infection, Immunity and Disease Mechanisms
School of Health Sciences and Social Care
Heinz Wolff Building
Brunel University
Uxbridge UB8 3PH
West London, UK

Page last updated: Friday 15 July 2011