Respiratory Physiology Research Group

The focus of research by the respiratory physiology grouping is broadly upon respiratory limitations to exercise tolerance. These limitations can arise from diseases such as asthma, but also from mechanical constraints imposed by the respiratory pump musculature.

We are perhaps best known for our research in respiratory muscle fatigue/training, an area where the group has taken a lead in firstly, describing fatigue and responses to training of the respiratory muscles, and secondly, in providing insights into underlying mechanisms. The group has also made major contributions to the understanding of the central and peripheral components of fatigue during exercise, especially in the presence of arterial hypoxaemia.

Our research on exercise-induced asthma (EIA) is also at the forefront, and extends from describing the prevalence of EIA in elite athletes, to understanding the physiological mechanisms. In the applied context, we offer services to athletes with breathing-related problems (eg exercise-induced asthma screening), as well as those seeking to minimise respiratory limitations to their performance.


Mechanisms by which inspiratory muscle training improves exercise performance
   

Staff Profiles

Highlighted Publications

PROF. ALISON McCONNELL

1. Kilding AE, Brown S & McConnell AK. (2010). Inspiratory muscle training improves 100 and 200 m swimming performance. European Journal of Applied Physiology 108, 505-511. (Abstract)

2. Lomax M & McConnell AK. (2009). Influence of prior activity (warm-up) and inspiratory muscle training upon between- and within-day reliability of maximal inspiratory pressure measurement. Respiration 78, 197-202. (Abstract)

3. How SC, Romer LM & McConnell AK. (2009). Acute effects of inspiratory pressure threshold loading upon airway resistance in people with asthma. Respir Physiol Neurobiol 166, 159-163.

4. McConnell A & Griffiths LS (2010). Acute cardiorespiratory responses to inspiratory pressure threshold loading. Medicine Science in Sport and Exercise 42,1696-1703. (Abstract)

PROF. IAN CAMPBELL

1. West CR, Campbell IG, Shave RE, Romer LM (2011). Effects of abdominal binding on cardiorespiratory function in cervical spinal cord injury. Respiratory Physiology & Neurobiology 180, 275-282

2. West CR, Campbell IG, Shave RE, Romer LM (2012). Resting cardiopulmonary function in Paralympic athletes with cervical spinal cord injury. Medicine Science in Sport and Exercise 44, 323-329

DR. LEE ROMER

1. Taylor, B. J., & Romer, L. M. (2008). Effect of expiratory muscle fatigue on exercise tolerance and locomotor muscle fatigue in healthy humans. Journal of Applied Physiology 104, 1442-1451. (Abstract)

2. Taylor, B. J., West, C. R., & Romer, L. M. (2010). No effect of arm-crank exercise on diaphragmatic fatigue or ventilatory constraint in Paralympic athletes with cervical spinal cord injury. Journal of Applied Physiology 109, 358-366. (Abstract)

3. Goodall, S., Ross, E. Z., & Romer, L. M. (2010). Effect of graded hypoxia on supraspinal contributions to fatigue after single leg knee-extensor contractions in humans. Journal of Applied Physiology. 109, 1842-1851 (Abstract)

4. Lovering, A. T., Romer, L. M., Haverkamp, H. C., Pegelow, D. F., Hokanson, J. S., & Eldridge, M. W. (2008). Intrapulmonary shunting and pulmonary gas exchange during normoxic and hypoxic exercise in healthy humans. Journal of Applied Physiology 104, 1418-1425. (Abstract)

DR. PASCALE KIPPELEN

1. Kippelen P, Larsson J, Anderson SD, Brannan JD, Delin I, Dahlen B, Dahlen SE (2010). Acute Effects of Beclomethasone on Hyperpnoea-Induced Bronchoconstriction. Med Sci Sports Exerc. 42, 273-80.

2. Fitch KD, Sue-Chu M, Anderson SD, Boulet LP, Hancox RJ, McKenzie DC, Backer V,Rundell KW, Alonso JM, Kippelen P, Cummiskey JM, Garnier A, Ljungqvist A (2008). Asthma and the elite athlete: summary of the International Olympic Committee's consensus conference. J Allergy Clin Immunol. 122, 254-260.

3. Anderson SD, Kippelen P (2008). Airway injury as a mechanism for exercise-induced bronchoconstriction in elite athletes. J Allergy Clin Immunol. 122, 225-235.

4. Kippelen P, Larsson J, Anderson SD, Brannan JD, Dahlén B, Dahlén SE (2010). Effect of sodium cromoglycate on mast cell mediators during hyperpnea in athletes. Med Sci Sports Exerc. 42, 1853-1860.

Page last updated: Tuesday 07 February 2012