Centre for Inflammation Research and Translational Medicine (CIRTM)

The Centre was established with the objective of bringing together a critical mass of internationally outstanding basic and clinical researchers tackling today’s global health challenges.

Impact and Innovation

Impact case studies

Resources for Industry Partners

Research within CIRTM

Research forms the core of the CIRTM, around which all our other activities (e.g. training, teaching, clinical care and outreach) occur. Multidisciplinary research within the CIRTM is investigator led and focuses on one or more of the following research areas:

Cardiovascular Diseases

Inflammation

Infections and Immunity

Microbiome and Health

Cancer

Microbial Resistance

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The mechanisms underlying adverse effects of pharmaceuticals

Completed

Understanding the effects of cyclo-oxygenase inhibition in the zebrafish

Completed

Understanding the effects of inflammation on brain and behaviour

Completed

Metabolic reprogramming for improved BCG vaccine efficacy

Completed

Early growth protein molecules and preventing autoimmune disease and cancer

Completed

Modelling infant leukaemia using gene editing technology

Completed

Reactivation of herpesviruses in Myalgic Encephalomyelitis

Ongoing

Novel approaches for testing metabolism disrupting chemicals

Ongoing

Human endogenous factors in the control of mycobacterial infection

Completed

Host-pathogen interactions in tuberculosis

Completed

A new cell and gene therapy approach for Friedreich's ataxia

Completed

Modelling adenoid cystic carcinoma in a mouse

Completed

Oncoprotein MYB in the head and neck cancer adenoid cystic carcinoma

Completed

Understanding and manipulating our immune system to protect against ageing

Ongoing

Investigating cerebral microvasculature dysfunction in stroke

Completed

Pharmacological strategies for resolution of inflammation

Completed

Promoting inflammation resolution in sickle cell disease

Ongoing

Investigating thrombo-inflammation associated with cardiovascular diseases

Completed

Innate immunity in bovine tuberculosis

Completed

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Our funding partners

We have great success at securing grant funding for our research and our partners include some of the biggest names in the area. 

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Watch our research videos

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Reducing inflammation in the brain after stroke

Professor Felicity Gavins explains her stroke research in The Royal Society video

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Understanding adenoid cystic carcinoma

Professor Arturo Sala explains his research with the Oracle Cancer Trust

Postgraduate research opportunities

Opportunities for research students

Browse PhD topic opportunities in Biomedical Sciences

Apply for a PhD in Biosciences

Specialist facilities and equipment 

The CIRTM resides within the Division of Biosciences at Brunel University London, with members taking full advantage of recent research infrastructure investments to support cutting edge research.

Advanced Bioprocessing Centre

The Centre has four dedicated labs with the latest analytical equipment as well as robot liquid handling systems for method development for new applications research in liquid flow technology.

Experimental Techniques Centre

Animal research at Brunel

Research using animals is often the only way to enhance our understanding and to ensure that newly developed medicines and treatments are safe to use.

The Pash Centre