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Martin, S., Tyrrell, J., Thomas, EL., Bown, MJ., Wood, AR., Beaumont, RN., et al. (2022) 'Disease consequences of higher adiposity uncoupled from its adverse metabolic effects using Mendelian randomisation'. eLife, 11. pp. 1 - 33. ISSN: 2050-084X Open Access Link

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Martin, S., Sorokin, EP., Thomas, EL., Sattar, N., Cule, M., Bell, JD. and et al. (2021) 'Estimating the Effect of Liver and Pancreas Volume and Fat Content on Risk of Diabetes: A Mendelian Randomization Study'. Diabetes Care, 0 (in press). pp. 1 - 9. ISSN: 0149-5992 Open Access Link

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Martin, S., Cule, M., Basty, N., Tyrrell, J., Beaumont, RN., Wood, AR., et al. (2021) 'Genetic Evidence for Different Adiposity Phenotypes and Their Opposing Influences on Ectopic Fat and Risk of Cardiometabolic Disease'. Diabetes, 70 (8). pp. 1843 - 1856. ISSN: 0012-1797 Open Access Link

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Rob Taal, H., St Pourcain, B., Thiering, E., Das, S., Mook-Kanamori, DO., Warrington, NM., et al. (2021) 'Common variants at 12q15 and 12q24 are associated with infant head circumference'. Nature Genetics, 44 (5). pp. 532 - 538. ISSN: 1061-4036

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Heald, AH., Martin, S., Fachim, H., Green, HD., Young, KG., Malipatil, N., et al. (2021) 'Genetically defined favourable adiposity is not associated with a clinically meaningful difference in clinical course in people with type 2 diabetes but does associate with a favourable metabolic profile'. Diabetic Medicine, 38 (9). pp. e14531. ISSN: 0742-3071 Open Access Link

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Erzurumluoglu, AM., Liu, M., Jackson, VE., Barnes, DR., Datta, G., Melbourne, CA., et al. (2020) 'Meta-analysis of up to 622,409 individuals identifies 40 novel smoking behaviour associated genetic loci'. Molecular Psychiatry, 25 (10). pp. 2392 - 2409. ISSN: 1359-4184

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Yaghootkar, H., Zhang, Y., Spracklen, CN., Karaderi, T., Huang, LO., Bradfield, J., et al. (2020) 'Genetic studies of leptin concentrations implicate leptin in the regulation of early adiposity'. Diabetes, 69 (12). pp. 2806 - 2818. ISSN: 0012-1797

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Vincent, EE. and Yaghootkar, H. (2020) 'Using genetics to decipher the link between type 2 diabetes and cancer: shared aetiology or downstream consequence?'. Diabetologia, 63 (9). pp. 1706 - 1717. ISSN: 0012-186X

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Yaghootkar, H., Whitcher, B., Bell, JD. and Thomas, EL. (2020) 'Ethnic differences in adiposity and diabetes risk – insights from genetic studies'. Journal of Internal Medicine, 288 (3). pp. 271 - 283. ISSN: 0954-6820

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Glastonbury, CA., Pulit, SL., Honecker, J., Censin, JC., Laber, S., Yaghootkar, H., et al. (2020) 'Machine Learning based histology phenotyping to investigate the epidemiologic and genetic basis of adipocyte morphology and cardiometabolic traits'. PLoS Computational Biology, 16 (8 August). pp. e1008044 - e1008044. ISSN: 1553-734X

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Parisinos, CA., Wilman, HR., Thomas, EL., Kelly, M., Nicholls, RC., McGonigle, J., et al. (2020) 'Genome-wide and Mendelian randomisation studies of liver MRI yield insights into the pathogenesis of steatohepatitis'. Journal of Hepatology, 73 (2). pp. 241 - 251. ISSN: 0168-8278

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Casanova, F., Wood, AR., Yaghootkar, H., Beaumont, RN., Jones, SE., Gooding, KM., et al. (2020) 'A Mendelian randomization study provides evidence that adiposity and dyslipidemia lead to lower urinary albumin-to-creatinine ratio, a marker of microvascular function'. Diabetes, 69 (5). pp. 1072 - 1082. ISSN: 0012-1797

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Metcalfe, LK., Krishnan, M., Turner, N., Yaghootkar, H., Merry, TL., Dewes, O., et al. (2020) 'The Māori and Pacific specific CREBRF variant and adult height'. International Journal of Obesity, 44 (3). pp. 748 - 752. ISSN: 0307-0565

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Jones, SE., van Hees, VT., Mazzotti, DR., Marques-Vidal, P., Sabia, S., van der Spek, A., et al. (2019) 'Genetic studies of accelerometer-based sleep measures yield new insights into human sleep behaviour'. Nature Communications, 10 (1). pp. 1585. ISSN: 2041-1723

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Jones, SE., Lane, JM., Wood, AR., van Hees, VT., Tyrrell, J., Beaumont, RN., et al. (2019) 'Genome-wide association analyses of chronotype in 697,828 individuals provides insights into circadian rhythms'. Nature Communications, 10 (1). pp. 343. ISSN: 2041-1723

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Yaghootkar, H., Abbasi, F., Ghaemi, N., Rabbani, A., Wakeling, MN., Eshraghi, P., et al. (2019) 'Type 1 diabetes genetic risk score discriminates between monogenic and Type 1 diabetes in children diagnosed at the age of <5 years in the Iranian population'. Diabetic Medicine, 36 (12). pp. 1694 - 1702. ISSN: 0742-3071

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Spracklen, CN., Karaderi, T., Yaghootkar, H., Schurmann, C., Fine, RS., Kutalik, Z., et al. (2019) 'Erratum: Exome-Derived Adiponectin-Associated Variants Implicate Obesity and Lipid Biology (The American Journal of Human Genetics (2019) 105(1) (15–28), (S0002929719301880), (10.1016/j.ajhg.2019.05.002))'. American Journal of Human Genetics, 105 (3). pp. 670 - 671. ISSN: 0002-9297

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Wilman, HR., Parisinos, CA., Atabaki-Pasdar, N., Kelly, M., Thomas, EL., Neubauer, S., et al. (2019) 'Genetic studies of abdominal MRI data identify genes regulating hepcidin as major determinants of liver iron concentration'. Journal of Hepatology, 71 (3). pp. 594 - 602. ISSN: 0168-8278

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Spracklen, CN., Karaderi, T., Yaghootkar, H., Schurmann, C., Fine, RS., Kutalik, Z., et al. (2019) 'Exome-Derived Adiponectin-Associated Variants Implicate Obesity and Lipid Biology'. American Journal of Human Genetics, 105 (1). pp. 15 - 28. ISSN: 0002-9297

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Tyrrell, J., Mulugeta, A., Wood, AR., Zhou, A., Beaumont, RN., Tuke, MA., et al. (2019) 'Using genetics to understand the causal influence of higher BMI on depression'. International Journal of Epidemiology, 48 (3). pp. 834 - 848. ISSN: 0300-5771

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Asl, SN., Vakili, R., Vakili, S., Soheilipour, F., Hashemipour, M., Ghahramani, S., et al. (2019) 'Wolcott-Rallison syndrome in Iran: A common cause of neonatal diabetes'. Journal of Pediatric Endocrinology and Metabolism, 32 (6). pp. 607 - 613. ISSN: 0334-018X

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Tuke, MA., Ruth, KS., Wood, AR., Beaumont, RN., Tyrrell, J., Jones, SE., et al. (2019) 'Mosaic Turner syndrome shows reduced penetrance in an adult population study'. Genetics in Medicine, 21 (4). pp. 877 - 886. ISSN: 1098-3600

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Justice, AE., Karaderi, T., Highland, HM., Young, KL., Graff, M., Lu, Y., et al. (2019) 'Protein-coding variants implicate novel genes related to lipid homeostasis contributing to body-fat distribution'. Nature Genetics, 51 (3). pp. 452 - 469. ISSN: 1061-4036 Open Access Link

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Pulit, SL., Stoneman, C., Morris, AP., Wood, AR., Glastonbury, CA., Tyrrell, J., et al. (2019) 'Meta-Analysis of genome-wide association studies for body fat distribution in 694 649 individuals of European ancestry'. Human Molecular Genetics, 28 (1). pp. 166 - 174. ISSN: 0964-6906

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Crawford, B., Craig, Z., Mansell, G., White, I., Smith, A., Spaull, S., et al. (2018) 'DNA methylation and inflammation marker profiles associated with a history of depression'. Human Molecular Genetics, 27 (16). pp. 2840 - 2850. ISSN: 0964-6906 Open Access Link

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Frayling, TM., Beaumont, RN., Jones, SE., Yaghootkar, H., Tuke, MA., Ruth, KS., et al. (2018) 'A Common Allele in FGF21 Associated with Sugar Intake Is Associated with Body Shape, Lower Total Body-Fat Percentage, and Higher Blood Pressure'. Cell Reports, 23 (2). pp. 327 - 336. ISSN: 2211-1247

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Beaumont, RN., Warrington, NM., Cavadino, A., Tyrrell, J., Nodzenski, M., Horikoshi, M., et al. (2018) 'Genome-wide association study of offspring birth weight in 86 577 women identifies five novel loci and highlights maternal genetic effects that are independent of fetal genetics'. Human Molecular Genetics, 27 (4). pp. 742 - 756. ISSN: 0964-6906

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Turcot, V., Lu, Y., Highland, HM., Schurmann, C., Justice, AE., Fine, RS., et al. (2018) 'Protein-altering variants associated with body mass index implicate pathways that control energy intake and expenditure in obesity'. Nature Genetics, 50 (1). pp. 26 - 35. ISSN: 1061-4036 Open Access Link

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Liu, DJ., Peloso, GM., Yu, H., Butterworth, AS., Wang, X., Mahajan, A., et al. (2017) 'Exome-wide association study of plasma lipids in >300,000 individuals'. Nature Genetics, 49 (12). pp. 1758 - 1766. ISSN: 1061-4036

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Yaghootkar, H., Bancks, MP., Jones, SE., McDaid, A., Beaumont, R., Donnelly, L., et al. (2017) 'Quantifying the extent to which index event biases influence large genetic association studies'. Human Molecular Genetics, 26 (5). pp. 1003 - 1017. ISSN: 0964-6906

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Lotta, LA., Gulati, P., Day, FR., Payne, F., Ongen, H., Van De Bunt, M., et al. (2017) 'Integrative genomic analysis implicates limited peripheral adipose storage capacity in the pathogenesis of human insulin resistance'. Nature Genetics, 49 (1). pp. 17 - 26. ISSN: 1061-4036

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Tyrrell, J., Wood, AR., Ames, RM., Yaghootkar, H., Beaumont, RN., Jones, SE., et al. (2017) 'Gene–obesogenic environment interactions in the UK Biobank study'. International Journal of Epidemiology, 46 (2). pp. 559 - 575. ISSN: 0300-5771

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Surendran, P., Drenos, F., Young, R., Warren, H., Cook, JP., Manning, AK., et al. (2016) 'Trans-ancestry meta-analyses identify rare and common variants associated with blood pressure and hypertension'. NATURE GENETICS, 48 (10). pp. 1151 - 1161. ISSN: 1061-4036 Open Access Link

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Jones, SE., Tyrrell, J., Wood, AR., Beaumont, RN., Ruth, KS., Tuke, MA., et al. (2016) 'Genome-Wide Association Analyses in 128,266 Individuals Identifies New Morningness and Sleep Duration Loci'. PLoS Genetics, 12 (8). pp. e1006125 - e1006125. ISSN: 1553-7390

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Yaghootkar, H., Lotta, LA., Tyrrell, J., Smit, RAJ., Jones, SE., Donnelly, L., et al. (2016) 'Genetic evidence for a link between favorable adiposity and lower risk of type 2 diabetes, hypertension, and heart disease'. Diabetes, 65 (8). pp. 2448 - 2460. ISSN: 0012-1797

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Kanoni, S., Masca, NGD., Stirrups, KE., Varga, TV., Warren, HR., Scott, RA., et al. (2016) 'Analysis with the exome array identifies multiple new independent variants in lipid loci'. Human Molecular Genetics, 25 (18). pp. ddw227 - ddw227. ISSN: 0964-6906 Open Access Link

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Lee, BP., Lloyd-Laney, HO., Locke, JM., McCulloch, LJ., Knight, B., Yaghootkar, H., et al. (2016) 'Functional characterisation of ADIPOQ variants using individuals recruited by genotype'. Molecular and Cellular Endocrinology, 428 (C). pp. 49 - 57. ISSN: 0303-7207

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Wood, AR., Tyrrell, J., Beaumont, R., Jones, SE., Tuke, MA., Ruth, KS., et al. (2016) 'Variants in the FTO and CDKAL1 loci have recessive effects on risk of obesity and type 2 diabetes, respectively'. Diabetologia, 59 (6). pp. 1214 - 1221. ISSN: 0012-186X

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Ruth, KS., Beaumont, RN., Tyrrell, J., Jones, SE., Tuke, MA., Yaghootkar, H., et al. (2016) 'Genetic evidence that lower circulating FSH levels lengthen menstrual cycle, increase age at menopause and impact female reproductive health'. Human Reproduction, 31 (2). pp. 473 - 481. ISSN: 0268-1161

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Tyrrell, J., Jones, SE., Beaumont, R., Astley, CM., Lovell, R., Yaghootkar, H., et al. (2016) 'Height, body mass index, and socioeconomic status: Mendelian randomisation study in UK Biobank'. BMJ (Online), 352. pp. i582 - i582. ISSN: 0959-8146

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Pilling, LC., Atkins, JL., Bowman, K., Jones, SE., Tyrrell, J., Beaumont, RN., et al. (2016) 'Human longevity is influenced by many genetic variants: Evidence from 75,000 UK Biobank participants'. Aging, 8 (3). pp. 547 - 560. ISSN: 1945-4589

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Fall, T., Xie, W., Poon, W., Yaghootkar, H., Magi, R., Knowles, JW., et al. (2015) 'Using genetic variants to assess the relationship between circulating lipids and type 2 diabetes'. Diabetes, 64 (7). pp. 2676 - 2684. ISSN: 0012-1797

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Yaghootkar, H., Stancáková, A., Freathy, RM., Vangipurapu, J., Weedon, MN., Xie, W., et al. (2015) 'Association analysis of 29,956 individuals confirms that a low- frequency variant at CCND2 halves the risk of type 2 diabetes by enhancing insulin secretion'. Diabetes, 64 (6). pp. 2279 - 2285. ISSN: 0012-1797

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