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Dr Luigi Margiotta-Casaluci

Dr Luigi Margiotta-Casaluci
Visiting Senior Lecturer - Life Sciences

Research supervision

Dr Luigi Margiotta-Casaluci is currently supervising the research activity of several PhD, MSc, and BSc students.

Current lab members:

  • Philip Marmon - PhD candidate. Philip's research is supported by BBSRC and AstraZeneca and is focused on advancing our undertanding of the pharmacological and toxicological profile of non-steroidal anti-inflammatory drugs (NSAIDs), such as ibuprofen and diclofenac.
  • Inês Moreira - PhD candidate. Inês is carrying out a project aimed at undertanding the effects of chronic inflammation on the brain. Her research is supported by Brunel University London via an Isambard grant.

Affiliated members:

  • Charles Hamilton - PhD candidate - University of Exeter. Charles is carrying out his PhD project in the lab of Professor Tyler at the University of Exeter, and he is supporterd by a BBSRC-AstraZeneca grant. His research is aimed at advancing the understanding of the biological effects triggered by early life exposure to synthetic glucocorticoids.

Past members

  • Hanna Dusza - Development of Adverse Outcome Pathways (AOPs) for cardiotoxicity mediated by L-type calcium channel blockade. (now at the University of Utrecht)

Every year, Dr Margiotta-Casaluci supervises both BSc and MSc students carrying out the research for their final project in the Margiotta-Casaluci Lab. Each student has the opportunity to work on unanswered research questions in the field of predictive and comparative pharmacology and toxicology, learning to use a combination of cutting-edge computational and experimental techniques. Past BSc and MSc lab members include:

  • Kiran Rakha - Intestinal microbiome and inflammation (now at the UK NHS) 
  • Joy Kayode - Predictive toxicology 
  • Shams Choudhury - Drug polypharmacology and mixture effects (now at the UK MHRA
  • Aitana Alzugaray - Inflammation and behaviour 
  • Isabelle Wetton - Immunomodulation and drug safety   

Other supervisory roles (e.g. Research Development Advisor, Second Supervisor)

  • Raquel Sales Gil - (Research Development Advisor). Raquel is a PhD student in Dr Vagnarelli's lab at Brunel University London/College of Health and Life Sciences. Her research is focused on undertanding the role of PP1 and environmental contaminants in heterochromatin establishment and maintainance. 
  • Rosie Williams - (Research Development Advisor). Rosie is a PhD student at the Zoological Society of London (ZSL). Her researchaims at to understanding the effects of persistent pollutants on the health of cetaceans and predicting how this will impact populations around the UK coast.