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Dr Luigi Margiotta-Casaluci

Dr Luigi Margiotta-Casaluci
Visiting Senior Lecturer - Life Sciences

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Marmon, P., Owen, S. and Margiotta-Casaluci, L. (2020) 'Pharmacology-informed prediction of the risk posed to fish by mixtures of non-steroidal anti-inflammatory drugs (NSAIDs) in the environment'. Environment International, 146. pp. 106222 - 106222. ISSN: 0160-4120 Open Access Link

Journal article

Legler, J., Zalko, D., Jourdan, F., Jacobs, M., Fromenty, B., Balaguer, P., et al. (2020) 'The goliath project: Towards an internationally harmonised approach for testing metabolism disrupting compounds'. International Journal of Molecular Sciences, 21 (10). pp. 1 - 18. ISSN: 1661-6596 Open Access Link

Journal article

Mahony, C., Ashton, RS., Birk, B., Boobis, AR., Cull, T., Daston, GP., et al. (2020) 'New ideas for non-animal approaches to predict repeated-dose systemic toxicity: Report from an EPAA Blue Sky Workshop'. Regulatory Toxicology and Pharmacology, 114. pp. 104668 - 104668. ISSN: 0273-2300 Open Access Link

Journal article

Rivetti, C., Allen, TEH., Brown, JB., Butler, E., Carmichael, PL., Colbourne, JK., et al. (2019) 'Vision of a near future: Bridging the human health–environment divide. Toward an integrated strategy to understand mechanisms across species for chemical safety assessment'. Toxicology in Vitro, 62 (February 2020). pp. 1 - 9. ISSN: 0887-2333 Open Access Link

Journal article

Margiotta-Casaluci, L., Dusza, H., Moreira, I., Winter, MJ. and Prior, H. (2019) 'Development of an adverse outcome pathway (AOP) for cardiotoxicity mediated by the blockade of L-type calcium channels'. United States. 1 Elsevier BV. pp. 106595. ISSN: 1056-8719

Conference paper

Margiotta-Casaluci, L., Owen, S., Rand-Weaver, M. and Winter, M. (2019) 'Testing the Translational Power of the Zebrafish: An Interspecies Analysis of Responses to Cardiovascular Drugs'. Frontiers in Pharmacology, 10 (JULY). pp. 893. ISSN: 1663-9812 Open Access Link

Journal article

Ellis, T., Margiotta-Casaluci, L., Pottinger, TG., Morris, S., Reese, RA., Sumpter, JP. and et al. (2019) 'Immunoassays are not immune to errors: Examples from two studies of steroid output from freshwater trout farms'. General and Comparative Endocrinology, 285 (1 January 2020). pp. 1 - 14. ISSN: 0016-6480

Journal article

Gunnarsson, L., Snape, JR., Verbruggen, B., Owen, SF., Kristiansson, E., Margiotta-Casaluci, L., et al. (2019) 'Pharmacology beyond the patient – The environmental risks of human drugs'. Environment International, 129. pp. 320 - 332. ISSN: 0160-4120 Open Access Link

Journal article

Tanoue, R., Margiotta-Casaluci, L., Huerta, B., Runnalls, TJ., Eguchi, A., Nomiyama, K., et al. (2019) 'Protecting the environment from psychoactive drugs: Problems for regulators illustrated by the possible effects of tramadol on fish behaviour'. Science of the Total Environment, 664. pp. 915 - 926. ISSN: 0048-9697 Open Access Link

Journal article

Villeneuve, DL., Angrish, MM., Fortin, MC., Katsiadaki, I., Leonard, M., Margiotta-Casaluci, L., et al. (2018) 'Adverse Outcome Pathway Networks II: Network Analytics.'. Environ Toxicol Chem, 37 (6). pp. 1734 - 1748. ISSN: 1552-8618 Open Access Link

Journal article

Knapen, D., Angrish, MM., Fortin, MC., Katsiadaki, I., Leonard, M., Margiotta-Casaluci, L., et al. (2018) 'Adverse Outcome Pathway Networks I: Development and Applications'. Environ Toxicol Chem, 37 (6). pp. 1723 - 1733. ISSN: 1552-8618 Open Access Link

Journal article

Tanoue, R., Margiotta-Casaluci, L., Huerta, B., Runnalls, TJ., Nomiyama, K., Kunisue, T., et al. (2017) 'Uptake and Metabolism of Human Pharmaceuticals by Fish - A Case Study with the Opioid Analgesic Tramadol.'. Environmental science & technology, 51 (21). pp. 12825 - 12835. ISSN: 1520-5851 Open Access Link

Journal article

Huerta, B., Margiotta-Casaluci, L., Rodríguez-Mozaz, S., Scholze, M., Winter, MJ., Barceló, D. and et al. (2016) 'Anti-anxiety drugs and fish behavior: Establishing the link between internal concentrations of oxazepam and behavioral effects'. Environmental Toxicology and Chemistry, 35 (11). pp. 2782 - 2790. ISSN: 0730-7268 Open Access Link

Journal article

Margiotta-Casaluci, L., Owen, SF., Huerta, B., Rodríguez-Mozaz, S., Kugathas, S., Barceló, D., et al. (2016) 'Internal exposure dynamics drive the Adverse Outcome Pathways of synthetic glucocorticoids in fish'. Scientific Reports, 6 (1). pp. 21978. ISSN: 2045-2322 Open Access Link

Journal article

Runnalls, TJ., Beresford, N., Kugathas, S., Margiotta-Casaluci, L., Scholze, M., Scott, AP. and et al. (2015) 'From single chemicals to mixtures-Reproductive effects of levonorgestrel and ethinylestradiol on the fathead minnow.'. Aquatic Toxicology, 169. pp. 152 - 167. ISSN: 1879-1514 Open Access Link

Journal article

Margiotta-Casaluci, L., Owen, SF., Cumming, RI., De Polo, A., Winter, MJ., Panter, GH., et al. (2014) 'Quantitative cross-species extrapolation between humans and fish: The case of the anti-depressant fluoxetine'. PLoS One, 9 (10). pp. e110467 - e110467. ISSN: 1932-6203 Open Access Link

Journal article

De Polo, A., Margiotta-Casaluci, L., Lockyer, AE. and Scrimshaw, MD. (2014) 'A new role for carbonic anhydrase 2 in the response of fish to copper and osmotic stress: Implications for multi-stressor studies'. PLoS ONE, 9 (10). pp. e107707 - e107707. ISSN: 1932-6203 Open Access Link

Journal article

Caldwell, DJ., Mastrocco, F., Margiotta-Casaluci, L. and Brooks, BW. (2014) 'An integrated approach for prioritizing pharmaceuticals found in the environment for risk assessment, monitoring and advanced research'. Chemosphere, 115 (1). pp. 4 - 12. ISSN: 0045-6535

Journal article

Sumpter, JP. and Margiotta-Casaluci, L. (2014) 'Are some invertebrates exquisitely sensitive to the human pharmaceutical Fluoxetine?'. Aquatic Toxicology, 146. pp. 259 - 260. ISSN: 0166-445X

Journal article

Rand-Weaver, M., Patel, A., Margiotta-Casaluci, L., Sumpter, JP., Panter, GH. and Owen, SF. (2013) 'The read-across hypothesis and environmental risk assessment of pharmaceuticals'. Environmental Science and Technology, 47 (20). pp. 11384 - 11395. ISSN: 0013-936X Open Access Link

Journal article

Margiotta-Casaluci, L., Courant, F., Antignac, JP., Le Bizec, B. and Sumpter, JP. (2013) 'Identification and quantification of 5α-dihydrotestosterone in the teleost fathead minnow (Pimephales promelas) by gas chromatography-tandem mass spectrometry'. General and Comparative Endocrinology, 191. pp. 202 - 209. ISSN: 0016-6480

Journal article

Margiotta-Casaluci, L., Hannah, RE. and Sumpter, JP. (2013) 'Mode of action of human pharmaceuticals in fish: The effects of the 5-alpha-reductase inhibitor, dutasteride, on reproduction as a case study'. Aquatic Toxicology, 128-129. pp. 113 - 123. ISSN: 0166-445X

Journal article

Brian, JV., Beresford, N., Margiotta-Casaluci, L. and Sumpter, JP. (2011) 'Preliminary data on the influence of rearing temperature on the growth and reproductive status of fathead minnows Pimephales promelas'. Journal of Fish Biology, 79 (1). pp. 80 - 88. ISSN: 1095-8649 Open Access Link

Journal article

Margiotta-Casaluci, L. and Sumpter, JP. (2011) '5α-Dihydrotestosterone is a potent androgen in the fathead minnow (Pimephales promelas)'. General and Comparative Endocrinology, 171 (3). pp. 309 - 318. ISSN: 0016-6480

Journal article

Runnalls, TJ., Margiotta-Casaluci, L., Kugathas, S. and Sumpter, JP. (2010) 'Pharmaceuticals in the aquatic environment: Steroids and anti-steroids as high priorities for research'. Human and Ecological Risk Assessment, 16 (6). pp. 1318 - 1338. ISSN: 1080-7039

Journal article