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A human IPS cell model for gene therapy vector safety evaluation

Funder: National Centre for the Replacement, Refinement and Reduction of Animals in Research
Duration: January 2017 - December 2019

Gene therapy genotoxicity project

People

Name Telephone Email Office
Professor Michael Themis Professor Michael Themis
Professor - Gene Therapy and Genotoxicity
(Principal investigator)
T: +44 (0)1895 267252
E: michael.themis@brunel.ac.uk
+44 (0)1895 267252 michael.themis@brunel.ac.uk Heinz Wolff 235

Outputs

Themis, M., Al-Haque, S., Wang, W., Strobel-Freidekind, O., Deichmann, A., Henkaerts, E., et al. (2021) 'Application of InGetox to assess the genotoxicity of LV and AAV vectors'.ASGCT, 23rd Annual Mee9ng. Virtual. 1 - 14 May. Human Gene Therapy. pp. A136 - A136. ISSN: 1043-0342 Open Access Link

Conference paper

Suleman, S., Payne, A., Bowden, J., Al Haque, S., Zhan, M., Fawaz, S., et al. (2021) 'Lentivirus tethering to the genome is associated with transcription factor binding sites that favour virus survival'.ESGCT Collaborative Virtual Congress. Virtual. 1 - 22 October. Human Gene Therapy. pp. A138 - A139. ISSN: 1043-0342 Open Access Link

Conference paper