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Colleges

Research degrees

Research students are welcomed to Brunel as valued members of our thriving, research-intensive community. Find out more about Research Degrees in Brunel. A research degree provides the opportunity to investigate a topic in depth, and contribute new knowledge to your discipline.

Proposed PhD Projects

Description
Supervisor
Funding
The role of PE/PPE proteins in tuberculosis
Tuberculosis remains one of the world’s biggest killers due to an infectious disease. There remains an urgent need for the development of effective vaccines and novel drug targets against the disease....
Anthony Tsolaki
Self Funded
Investigating molecular disease mechanisms and therapy of Friedreich ataxia
Friedreich ataxia (FRDA) is a lethal inherited disease caused by GAA trinucleotide repeat expansion mutation within the FXN gene, leading to epigenetic modification of the FXN gene, decreased levels o...
Sara Anjomani Virmouni
Self Funded
Repo-Man function in embryogenesis and differentiation
Repo-Man (CDCA2) is a Protein Phosphatase 1 (PP1) targeting subunit that has been shown to be an important regulator of cell division. Recent studied from our laboratory have also shown that that Repo...
Paola Vagnarelli
Self Funded
Inhibiting cell metabolism to enhance tumour cell death
As you read this, millions of your cells from your body are dying. Do not panic – this is not bad news. Most of them are either superfluous or potentially harmful, so you are better off without them. ...
Self Funded
Study of the exosomes: RNA composition of exosomes as potential biomarkers for cancer; Exosomes as a delivery vehicle for therapeutic shRNAs
Exosomes are membrane microvesicles that are secreted by many cell types and the tumour cells are thought to generate a larger number of such vesicles. Exosomes contain a large set of the specific RNA...
Evgeny Makarov
Self Funded
The effect on genome behaviour of growing cells in 3D matricies
There has been a small amount of evidence in the literature that growing cells in 3D scaffolds instead of 2D monolayers alters genome behaviour and organisation such that nuclear structure is altered ...
Self Funded
Telomere length elongation following treatment with chemotherapeutic drugs.
Aim:  To investigate the mechanisms which leads to telomere length elongation after treatment with tricostatin A and azacytidine. Telomeres are specialised structures, which are present at the ends of...
Terry Roberts
Self Funded
Role of CDCA/PP1 in Triple Negative Breast Cancer (TNBC)
Estrogen, progesterone, and HER2 receptor-negative (triple-negative breast cancers TNBC) encompass the most clinically challenging subtype for which targeted therapeutics are lacking.  To identify cri...
Paola Vagnarelli
Self Funded
The mutations in TP53 gene from the glioma patients that trigger the aberrant pre-mRNA splicing
TP53 gene encodes the “Tumour Protein” p53 which plays a central role in cell cycle regulation. This protein is widely considered as the “Guardian of the Genome” for maintaining genetic stability. A m...
Evgeny Makarov
Self Funded
Central Nervous system Gene therapy to treat obesity Bardet-Biedl Syndrome (BBS). Analysis of the BBS brain development
Bardet-Biedl syndrome (BBS) is a debilitating, often life-limiting heritable multisystem disorder caused by dysfunction of non-motile cilia (ciliopathy). There is currently no cure for BBS, a disease ...
Victor Hernandez
Self Funded

 

Funding for doctoral studies

A number of studentships and other research funding opportunities are available at Brunel. Please see full list here: Research degree funding. 

Choosing your supervisor

Our researchers create knowledge and advance understanding, and equip versatile graduates with the confidence to apply what they have learnt for the benefit of society. Browse the list of the members of our Theme to select your potential supervisor here. You are welcome to approach your potential supervisor directly to discuss your research interests.

All research degrees are administered by the Postgraduate Programmes Office in Colleges. Once you have identified your area of research and a potential supervisor, please use the contact details provided here for enquiries.