Projects Common genetic variants that increase the risk of cancer Ongoing Radiation exposure and heritable genetic effects Ongoing How do cells divide? Chromatin re-organisation from mitosis to G1 Ongoing Investigating the role of CDCA2 molecule in neuroblastoma Ongoing Statistical modelling of multi-omics data Ongoing Side effects of gene therapy vectors Completed Modelling adenoid cystic carcinoma in a mouse Completed A new cell and gene therapy approach for Friedreich's ataxia Ongoing Preclinical studies of the inherited disease Friedreich ataxia Completed Bloodwise Ongoing Drug rescue of frataxin-dependent neural and cardiac pathophysiology in FA Completed Modelling infant leukaemia using gene editing technology Ongoing Protein Phosphatase 1 (PP1) in the Regulation of Mitotic Exit and Nuclear Organisation Completed Stem cell mitotic response to damage in old and young Drosophila melanogaster Completed Chromosome dynamics and Nuclear Motors – Chromobility Completed Cytogenetic Assessment of British Nuclear Test Veterans and their Offspring Completed Host: Pathogen interactions through the host genome Completed Drug treatments lead to Correction of Aberrant Genome Behaviour in Cancer and Immortalised Cells Completed Understanding and Treatment of Hutchinson-Gilford Progeria Syndrome Completed Evaluation of oligonucleotides for therapy of Friedreich ataxia Completed