Ovarian cancer is a lethal gynaecological malignancy that affects over 295,000 women globally, with a 20% survival rate for advanced stage. Often diagnosed at a late stage, due to the non-specific nature of symptoms, detection of ovarian cancer at an early stage is paramount. The discovery of novel hormones and influencers of the tumour microenvironment provide a promising avenue of research for the identification of cancer biomarkers. This project aims to expand research of a novel glucogenic hormone within the tumour microenvironment using traditional mono-layer tissue culture techniques as well as 3D co-culture organ-on-a-chip technology in addition to clinical liquid biopsies in order to advance the molecular understanding of ovarian cancer aetiology.
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Related Research Group(s)
Organ-on-a-Chip - The group’s main research focus is on women’s health and developing four main organ-on-a-chip (OOC) models: the breast, vagina, ovary, and placenta.
Project last modified 21/04/2021