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PhD topics for research students

Find below a list of currently available self-funded PhD topics.

We encourage all students to contact the supervisor or the alternative contact person for more information and an informal chat to discuss the process of applying and preparing your research statement. For more information on how to apply click here.

Description
Supervisor
Application Deadline
Funding
Role of cilia in oncogenic signaling and drug resistance
Primary cilia are microtubule-based antennae that detect mechanical and chemical stimuli. Although cilia house a number of oncogenic molecules (including Smoothened, KRAS, EGFR, and PDGFR), their prec...
26/05/2022

Self Funded

Self Funded
Establishing the fresh water snail, Biomphalaria glabrata as a new model of ageing to study the effects of senotherapeutic drugs on life-span
Biomphalaria glabrata is a freshwater tropical snail that is the intermediate host for the human neglected disease Schistosomiasis. Our laboratory have evidence that a mechanism that regulates gene mo...
26/05/2022

Self Funded

Self Funded
Interplay between genetic and environmental factors and risk of cardiovascular disease
Cardiovascular diseases including hypertension, myocardial infarction, heart failure, and stroke are the leading causes of mortality worldwide and are expected to keep rising. Modifiable and non-modif...
26/05/2022

Self Funded

Self Funded
Involvement of matricellular proteins in the dynamic interaction between tumour and host cells
Tumour growth depends on the crosstalk between malignant and surrounding stromal cells (fibroblasts, osteoblasts, endothelial cells and inflammatory cells). Malignant cells secrete soluble proteins th...
26/05/2022

Self Funded

Self Funded
Involvement of the matrix protein SPARC in the dynamic interaction between tumour and host cells
Tumour growth depends on the crosstalk between malignant and surrounding stromal cells (fibroblasts, osteoblasts, endothelial cells and inflammatory cells). Malignant cells secrete soluble proteins th...
26/05/2022

Self Funded

Self Funded
Brk and mTOR signalling: implications for Taxol resistance
One of the major causes of death amongst breast cancer patients is due to the development of distal metastases and the acquisition of resistance to chemotherapeutic agents. There is a scientific and c...
26/05/2022

Self Funded

Self Funded
Understanding and manipulating our immune system to protect against ageing
Ageing is the most important non-modifiable risk factor for a number of diseases and conditions of the immune system including ischaemia reperfusion injury (e.g. myocardial infarction and stroke), can...
26/05/2022

Self Funded

Self Funded
Role of primary cilia in lung carcinogenesis (partially funded MPhil)
This is an MPhil Project only. Bench Fees will be covered. Cilia are antennae-like sensory organelles that detect mechanical and chemical stimuli. The physiological importance of cilia is highlighted...
26/05/2022

Partially Funded

Partially Funded
Mechanisms of cilia biogenesis and signalling
Cilia are sensory organelles that detect mechanical and chemical stimuli from the environment. They arise from centrioles and function as “antennae” that receive and integrate extracellular signals. T...
26/05/2022

Self Funded

Self Funded
Emotionally intelligent artificial conversational agents for higher education or healthcare
Artificial conversational agents, can be embodied (physical robots or digital avatars on a screen) or not embodied (chat-bots or digital assistants). Agents may be able to converse but they can also a...
22/05/2022

Self Funded

Self Funded