The biannual Nuclear Envelope and Chromatin Organisation meeting returns for its 11th edition, following the success of the 2024 meeting. Use the "Book Now" link above to register.
We welcome the UK nuclear periphery network (and beyond), working on diverse aspects of the nuclear lamina, canonical and non-canonical NPC functions, genome organisation at the periphery, and the roles of peripheral proteins regulating nuclear shape, stiffness, and the cell cycle in health and disease. The conference dinner is included in the registration and will take place on site in the Lancaster Hotel
All talks will be selected from abstracts, with additional opportunities for poster and flash talk presentations. Registration fees have been kept low (free for students and technicians) to encourage whole lab participation and ensure that at least one member from each lab presents orally.
Abstract submission deadline: Friday 2 October 2026
Please send talk titles and abstracts to: neco.abstracts@gmail.com
Sponsorship
We are delighted to acknowledge the generous support of our sponsors:
Registration Fees
- Principal Investigators – £35
- Postdoctoral Researchers – £25
- PhD/Master’s Students & Technicians – FREE
(Includes all sessions and on-site catering)
For payment instructions:
Form: NECO 2026 Registration Form
Please follow the Instructions on the form and make payment using the payment link: https://ip.e-paycapita.com/AIP/itemSelectionPage.do?link=showItemSelectionPage&siteId=46&languageCode=EN&source=AIP&fc=MI
For queries, please contact:
ines.castro@brunel.ac.uk
joseph.hetmanski@brunel.ac.uk
Meeting Schedule
Thursday 5th November
12pm – 12.40pm –Registration and lunch
12.40pm – Opening remarks from organisers and short talk from Pamela Swiatlowska, Guest Co-Editor of a Special Issue "Nuclear Remodelling and Genome Organization in Cardiovascular Development and Disease" in the Journal of Cardiovascular Disease and Development
1pm – Peijun Zhang, University of Oxford: “Chromatin Dynamics and HIV-1 Nuclear Transport”
1.30pm – Marta Olivera, Queen Mary University of London: “HIV-1 Vpr drives targeted chromatin remodelling and transcriptional reprogramming in resting CD4 T cells”
2pm – Matthew Whelan, Queen Mary University London: “HIV-1 signalling remodels nuclear pores to licence infection”
2.30pm – Ines Castro, Brunel University of London: “Nuclear Pore Complexes: Diversity in Nuclear Basket Composition”
3pm – 3.30pm – Coffee Break
3.30pm – Gian De Nicola, King’s College London: “Lamin B1, Karyoptosis and the Fragile Nucleus: from nuclear instability to cell death in cardiovascular and neurodegenerative disease.”
4pm – Julia Madsen-Østerbye, University of Oslo: “FPLD2 lamin A mutation suppresses adipogenesis and remodels enhancer accessibility”
4.30pm – Diana Rubio Contreras, University of Sussex: “DNA damage at Lamina Associated Domains triggers nuclear envelope reorganization and chromatin detachment to prevent nuclear envelope blebbing and genome instability”
5pm – Christopher Eskiw, University of Saskatchewan: “The anaphase promoting complex targets the toxic protein Progerin for ubiquitin-dependent degradation via autophagy”
5.30pm – Selected Flash-Talks and Poster Session
6.30pm – Evening reception and buffet in the Lancaster Hotel
Friday 6th November
9.30am – Adam Byron, University of Manchester: “Mechanosensitive adhesion networks at the nucleus: linking the extracellular matrix to gene regulation in cancer”
10am – Pamela Swiatlowska, Queen Mary University of London: “Nuclear invaginations as mechanosensitive microdomains regulating cardiomyocyte nuclear architecture and function”
10.30am – Qiuping Zhang, King’s College London: “Nesprin-1/LINC Dysfunction Disrupts Perinuclear Microtubule Organisation”
11am – 11.20am – Coffee Break
11.20am – Matt Stroud, King’s College London: “Targeting PPARa to modulate dysfunction in Lem2 L13R cardiomyopathy”
11.50m – Elvira Infante, The Francis Crick Institute: “Mechano-chemical regulation of protein translocation through the nuclear pore.”
12.20pm – Vanja Pekovic-Vaughan, University of Liverpool: “Lamin A as a novel modulator of the circadian clockwork: implications for skeletal muscle homeostasis and therapeutic interventions”
12.40pm – 1.40pm – Lunch and Poster Session
1.40pm – Matthias Achrainer, University of Galway: “Unrevealing the role of lamin-genes in the closest relative of animal”
2pm – Qingqin Ji, University of Edinburgh: “Gene Repositioning at Nuclear Envelope Invaginations Is Driven by Smooth Muscle Cell Phenotypic Switching”
2.20pm – George Doherty, King’s College London: “Investigating Dynamic Changes in Cardiomyocyte Nuclear Morphology of Intact, Beating Hearts”
2.40pm – Fathiya Nairoukh, King’s College London, University of Jerusalem: “Investigating the mechanisms of an LMNA mutation in atypical progeria syndrome and severe cardiomyopathy”
3pm – Rita Torres Pereira, Brunel University of London: “The Impact of Disease-Specific Lamin A Mutations in Peripheral Chromatin Organisation and Nuclear Envelope Function.”
3.20pm – Dana Lorber, Weizmann Institute of Science: “LINC-dependent chromatin tethering to the nuclear envelope correlates with chromatin-RNAPII association and asymmetric reciprocal organisation”
3.40pm – Closing remarks, prizes and discussion of 12th NECO meeting
Accommodation
Accommodation is not included. Nearby options include:
- Lancaster Hotel (on campus)
- Lyttleton Lodge
- The Red Lion
- Watersedge canal cottages
- Premier Inn (Uxbridge town centre)
Transport & Location
The meeting will take place in Brunel University of London, in the Michael Sterling Building. Please view the campus map (grid reference D4).
Brunel is located in Uxbridge, West London, with excellent transport links:
- Close to M25, M4, and M40
- Near Uxbridge Underground Station (Metropolitan & Piccadilly lines)
- Near West Drayton (Elizabeth Line)
- Close to Heathrow Airport
More information: brunel.ac.uk/about/finding-us