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Dr Ansar Pathan

Dr Ansar Pathan
Lecturer

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Rowland, R., Pathan, AA., Satti, I., Poulton, ID., Matsumiya, MML., Whittaker, M., et al. (2013) 'Safety and immunogenicity of an FP9-vectored candidate tuberculosis vaccine (FP85A), alone and with candidate vaccine MVA85A in BCG-vaccinated healthy adults: A phase i clinical trial'. Human Vaccines and Immunotherapeutics, 9 (1). pp. 50 - 62. ISSN: 2164-5515

Journal article

Pathan, AA., Minassian, AM., Sander, CR., Rowland, R., Porter, DW., Poulton, ID., et al. (2012) 'Effect of vaccine dose on the safety and immunogenicity of a candidate TB vaccine, MVA85A, in BCG vaccinated UK adults'. Vaccine, 30 (38). pp. 5616 - 5624. ISSN: 0264-410X

Journal article

Rowland, R., Brittain, N., Poulton, ID., Minassian, AM., Sander, C., Porter, DW., et al. (2012) 'A review of the tolerability of the candidate TB vaccine, MVA85A compared with BCG and Yellow Fever vaccines, and correlation between MVA85A vaccine reactogenicity and cellular immunogenicity'. Trials in Vaccinology, 1. pp. 27 - 35. ISSN: 1879-4378 Open Access Link

Journal article

Griffiths, KL., Pathan, AA., Minassian, AM., Sander, CR., Beveridge, NER., Hill, AVS., et al. (2011) 'Th1/Th17 Cell Induction and Corresponding Reduction in ATP Consumption following Vaccination with the Novel Mycobacterium tuberculosis Vaccine MVA85A'. PLoS One, 6 (8). pp. e23463 - e23463. ISSN: 1932-6203 Open Access Link

Journal article

Beveridge, NER., Price, DA., Casazza, JP., Pathan, AA., Sander, CR., Asher, TE., et al. (2011) 'Correction: Immunisation with BCG and recombinant MVA85A induces long-lasting, polyfunctional Mycobacterium tuberculosis-specific CD4+ memory T lymphocyte populations'. European Journal of Immunology, 41 (5). pp. 1501 - 1501. ISSN: 0014-2980

Journal article

Minassian, AM., Rowland, R., Beveridge, NE., Poulton, ID., Satti, I., Harris, S., et al. (2011) 'A Phase I study evaluating the safety and immunogenicity of MVA85A, a candidate TB vaccine, in HIV-infected adults'. BMJ Open, 1 (2). pp. e000223 - e000223. ISSN: 2044-6055 Open Access Link

Journal article

Behboudi, S., Alisa, A., Boswell, S., Anastassiou, J., Pathan, AA. and Williams, R. (2010) 'Expansion of anti-AFP Th1 and Tc1 responses in hepatocellular carcinoma occur in different stages of disease.'. British Journal of Cancer, 102 (4). pp. 748 - 753. ISSN: 0007-0920 Open Access Link

Journal article

Lalvani, A. and Pathan, AA. (2010) 'Tuberculosis Diagnostic Test'. Available at: http://www.implu.com/patent_applicant/1244135.

Patent

De Cassan, SC., Pathan, AA., Sander, CR., Minassian, A., Rowland, R., Hill, AVS., et al. (2010) 'Investigating the induction of vaccine-induced Th17 and regulatory T cells in healthy, Mycobacterium bovis BCG-immunized adults vaccinated with a new tuberculosis vaccine, MVA85A'. Clinical and Vaccine Immunology, 17 (7). pp. 1066 - 1073. ISSN: 1556-6811

Journal article

Todryk, SM., Pathan, AA., Keating, S., Porter, DW., Berthoud, T., Thompson, F., et al. (2009) 'The relationship between human effector and memory T cells measured by ex vivo and cultured ELISPOT following recent and distal priming'. Immunology, 128 (1). pp. 83 - 91. ISSN: 0019-2805

Journal article

Sander, CR., Pathan, AA., Beveridge, NE., Poulton, I., Minassian, A., Alder, N., et al. (2009) 'Safety and immunogenicity of a new tuberculosis vaccine, MVA85A, in mycobacterium tuberculosis-infected individuals'. American Journal of Respiratory and Critical Care Medicine, 179 (8). pp. 724 - 733. ISSN: 1073-449X Open Access Link

Journal article

Whelan, KT., Pathan, AA., Sander, CR., Fletcher, HA., Poulton, I., Alder, NC., et al. (2009) 'Safety and immunogenicity of boosting BCG vaccinated subjects with BCG: comparison with boosting with a new TB vaccine, MVA85A.'. PLoS One, 4 (6). pp. e5934 - e5934. ISSN: 1932-6203 Open Access Link

Journal article

Smith, SG., Joosten, SA., Verscheure, V., Pathan, AA., McShane, H., Ottenhoff, TH., et al. (2009) 'Identification of major factors influencing ELISpot-based monitoring of cellular responses to antigens from Mycobacterium tuberculosis.'. PLoS One, 4 (11). pp. e7972 - e7972. ISSN: 1932-6203 Open Access Link

Journal article

Beveridge, NER., Fletcher, HA., Hughes, J., Pathan, AA., Scriba, TJ., Minassian, A., et al. (2008) 'A comparison of IFNγ detection methods used in tuberculosis vaccine trials'. Tuberculosis, 88 (6). pp. 631 - 640. ISSN: 1472-9792

Journal article

Fletcher, HA., Pathan, AA., Berthoud, TK., Dunachie, SJ., Whelan, KT., Alder, NC., et al. (2008) 'Boosting BCG vaccination with MVA85A down-regulates the immunoregulatory cytokine TGF-β1'. Vaccine, 26 (41). pp. 5269 - 5275. ISSN: 0264-410X

Journal article

McShane, H., Pathan, AA., Hill, A. and Gilbert, SC. (2008) 'Compositions for Immunizing Against Mycobacterium'. Available at: http://www.faqs.org/patents/app/20080226678.

Patent

Alisa, A., Boswell, S., Pathan, AA., Ayaru, L., Williams, R. and Behboudi, S. (2008) 'Human CD4+ T cells recognize an epitope within α-fetoprotein sequence and develop into TGF-β-producing CD4 + T cells'. Journal of Immunology, 180 (7). pp. 5109 - 5117. ISSN: 0022-1767

Journal article

Beveridge, NER., Price, DA., Casazza, JP., Pathan, AA., Sander, CR., Asher, TE., et al. (2007) 'Immunisation with BCG and recombinant MVA85A induces long-lasting, polyfunctional Mycobacterium tuberculosis-specific CD4 + memory T lymphocyte populations'. European Journal of Immunology, 37 (11). pp. 3089 - 3100. ISSN: 0014-2980

Journal article

Pathan, AA., Sander, CR., Fletcher, HA., Poulton, I., Alder, NC., Beveridge, NER., et al. (2007) 'Boosting BCG with recombinant modified vaccinia ankara expressing antigen 85A: Different boosting intervals and implications for efficacy trials'. PLoS ONE, 2 (10). ISSN: 1932-6203 Open Access Link

Journal article

Ayaru, L., Pereira, SP., Alisa, A., Pathan, AA., Williams, R., Davidson, B., et al. (2007) 'Unmasking of α-fetoprotein-specific CD4+ T cell responses in hepatocellular carcinoma patients undergoing embolization'. Journal of Immunology, 178 (3). pp. 1914 - 1922. ISSN: 0022-1767

Journal article

Gilbert, SC., Moorthy, VS., Andrews, L., Pathan, AA., McConkey, SJ., Vuola, JM., et al. (2006) 'Synergistic DNA-MVA prime-boost vaccination regimes for malaria and tuberculosis'. Vaccine, 24 (21). pp. 4554 - 4561. ISSN: 0264-410X

Journal article

Alisa, A., Ives, A., Pathan, AA., Navarrete, CV., Williams, R., Bertoletti, A. and et al. (2005) 'Analysis of CD4+ T-cell responses to a novel α-fetoprotein-derived epitope in hepatocellular carcinoma patients'. Clinical Cancer Research, 11 (18). pp. 6686 - 6694. ISSN: 1078-0432

Journal article

McShane, H., Pathan, AA., Sander, CR., Goonetilleke, NP., Fletcher, HA. and Hill, AVS. (2005) 'Boosting BCG with MVA85A: The first candidate subunit vaccine for tuberculosis in clinical trials'. Tuberculosis, 85 (1-2 SPEC.ISS.). pp. 47 - 52. ISSN: 1472-9792

Journal article

McShane, H., Pathan, AA., Sander, CR., Goonetilleke, NP., Fletcher, HA. and Hill, AVS. (2005) 'Boosting BCG with MVA85A: the first candidate subunit vaccine for tuberculosis in clinical trials'. Tuberculosis, 85 (1-2). pp. 47 - 52. ISSN: 1472-9792

Journal article

Wilkinson, KA., Wilkinson, RJ., Pathan, A., Ewer, K., Prakash, M., Klenerman, P., et al. (2005) 'Ex Vivo Characterization of Early Secretory Antigenic Target 6-Specific T Cells at Sites of Active Disease in Pleural Tuberculosis'. Clinical Infectious Diseases, 40 (1). pp. 184 - 187. ISSN: 1058-4838

Journal article

Liebeschuetz, S., Bamber, S., Ewer, K., Deeks, J., Pathan, AA. and Lalvani, A. (2004) 'Diagnosis of tuberculosis in South African children with a T-cell-based assay: A prospective cohort study'. Lancet, 364 (9452). pp. 2196 - 2203. ISSN: 0140-6736

Journal article

McShane, H., Pathan, AA., Sander, CR., Keating, SM., Gilbert, SC., Huygen, K., et al. (2004) 'Recombinant modified vaccinia virus Ankara expressing antigen 85A boosts BCG-primed and naturally acquired antimycobacterial immunity in humans'. Nature Medicine, 10 (11). pp. 1240 - 1244. ISSN: 1078-8956

Journal article

Brookes, RH., Pathan, AA., McShane, H., Hensmann, M., Price, DA. and Hill, AVS. (2003) 'CD8+ T cell-mediated suppression of intracellular Mycobacterium tuberculosis growth in activated human macrophages'. European Journal of Immunology, 33 (12). pp. 3293 - 3302. ISSN: 0014-2980

Journal article

Lalvani, A. and Pathan, AA. (2003) 'Detection of CD8+ T cell responses to M. tuberculosis'. Available at: http://www.patentvest.com/console/reports/docs/grant/07115361.html.

Patent

McConkey, SJ., Reece, WHH., Moorthy, VS., Webster, D., Dunachie, S., Butcher, G., et al. (2003) 'Enhanced T-cell immunogenicity of plasmid DNA vaccines boosted by recombinant modified vaccinia virus Ankara in humans'. Nature Medicine, 9 (6). pp. 729 - 735. ISSN: 1078-8956

Journal article

Chapman, ALN., Munkanta, M., Wilkinson, KA., Pathan, AA., Ewer, K., Ayles, H., et al. (2002) 'Rapid detection of active and latent tuberculosis infection in HIV-positive individuals by enumeration of Mycobacterium tuberculosis-specific T cells'. AIDS, 16 (17). pp. 2285 - 2293. ISSN: 0269-9370

Journal article

Pathan, AA., Wilkinson, KA., Klenerman, P., McShane, H., Davidson, RN., Pasvol, G., et al. (2001) 'Direct ex vivo analysis of antigen-specific IFN-γ-secreting CD4 T cells in mycobacterium tuberculosis-infected individuals: Associations with clinical disease state and effect of treatment'. Journal of Immunology, 167 (9). pp. 5217 - 5225. ISSN: 0022-1767

Journal article

Lalvani, A., Pathan, AA., Durkan, H., Wilkinson, KA., Whelan, A., Deeks, JJ., et al. (2001) 'Enhanced contact tracing and spatial tracking of Mycobacterium tuberculosis infection by enumeration of antigen-specific T cells'. Lancet, 357 (9273). pp. 2017 - 2021. ISSN: 0140-6736

Journal article

Lalvani, A., Pathan, AA., McShane, H., Wilkinson, RJ., Latif, M., Conlon, CP., et al. (2001) 'Rapid detection of Mycobacterium tuberculosis infection by enumeration of antigen-specific T cells.'. Am J Respir Crit Care Med, 163 (4). pp. 824 - 828. ISSN: 1073-449X

Journal article

Lalvani, A., Nagvenkar, P., Udwadia, Z., Pathan, AA., Wilkinson, KA., Shastri, JS., et al. (2001) 'Enumeration of T cells specific for RD1-encoded antigens suggests a high prevalence of latent Mycobacterium tuberculosis infection in healthy urban Indians'. Journal of Infectious Diseases, 183 (3). pp. 469 - 477. ISSN: 0022-1899

Journal article

Pathan, AA., Wilkinson, KA., Wilkinson, RJ., Latif, M., McShane, H., Pasvol, G., et al. (2000) 'High frequencies of circulating IFN-γ-secreting CD8 cytotoxic T cells specific for a novel MHC class I-restricted Mycobacterium tuberculosis epitope in M. tuberculosis-infected subjects without disease'. European Journal of Immunology, 30 (9). pp. 2713 - 2721. ISSN: 0014-2980

Journal article

Lalvani, A., Moris, P., Voss, G., Pathan, AA., Kester, KE., Brookes, R., et al. (1999) 'Potent induction of focused Th1-type cellular and humoral immune responses by RTS,S/SBAS2, a recombinant Plasmodium falciparum malaria vaccine'. Journal of Infectious Diseases, 180 (5). pp. 1656 - 1664. ISSN: 0022-1899

Journal article

Lalvani, A., Brookes, R., Wilkinson, RJ., Malin, AS., Pathan, AA., Andersen, P., et al. (1998) 'Human cytolytic and interferon γ-secreting CD8+ T lymphocytes specific for Mycobacterium tuberculosis'. Proceedings of the National Academy of Sciences of the United States of America, 95 (1). pp. 270 - 275. ISSN: 0027-8424

Journal article

Lalvani, A., Dong, T., Ogg, G., Pathan, AA., Newell, H., Hill, AVS., et al. (1997) 'Optimization of a peptide-based protocol employing IL-7 for in vitro restimulation of human cytotoxic T lymphocyte precursors'. Journal of Immunological Methods, 210 (1). pp. 65 - 77. ISSN: 0022-1759

Journal article

Pathan, AA., Green, T., Brown, J. and Navarrete, C. (1992) 'Possible role of amino acids on the β pleated sheet of HLA-DR molecule on the binding of a polymorphic Moab MO2P5D7'. European Journal of Immunogenetics, 19 (6). pp. 465. ISSN: 0960-7420

Journal article

Pathan, AA., Green, T., Brown, J. and Navarrete, C. (1991) 'Production and characterisation of a polymorphic HLA-DR monoclonal antibody by using transfectant L-cells', in Tsuji, K., Aizawa, M. and Sasazuki, T. (eds.) HLA 1991: Proceedings of the Eleventh International Histocompatibility Workshop and Conference. Oxford Science Publications. , 1. pp. 933 - 934. ISBN 10: 0-19-262390-7.

Book chapter