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Professor Felicity Gavins

Professor Felicity Gavins
Professor - Pharmacology

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Boltersdorf, T., Gavins, FNE. and Long, NJ. (2021) 'Long-lived lanthanide emission via a pH-sensitive and switchable LRET complex'. Chemical Science, 12 (25). pp. 1 - 5. ISSN: 2041-6520 Open Access Link

Journal article

Ansari, J. and Gavins, FNE. (2021) 'The Impact of Thrombo‐inflammation on the Cerebral Microcirculation'. Microcirculation, 28 (3). pp. e12689. ISSN: 1073-9688 Open Access Link

Journal article

Ansari, J., Senchenkova, EY., Vital, SA., Al-Yafeai, Z., Kaur, G., Sparkenbaugh, E., et al. (2021) 'Targeting AnxA1/Fpr2/ALX Regulates Neutrophil Function Promoting Thrombo-Inflammation Resolution in Sickle Cell Disease'. Blood, in press (11). pp. 1538 - 1549. ISSN: 0006-4971 Open Access Link

Journal article

Ansari, J., Vital, S., Esen, E. and Gavins, F. (2021) 'Targeting Peptidyl Arginine Deiminase 4 and NADPH Oxidase Pathways Regulates Neutrophil Dependent Thrombo-inflammation'.Pharmacology 2020.. ELECTR NETWORK. 1 - 18 December. WILEY. pp. 409 - 410. ISSN: 0007-1188

Conference paper

Vital, SA., Senchenkova, EY., Ansari, J. and Gavins, FNE. (2020) 'Targeting AnxA1/Formyl Peptide Receptor 2 Pathway Affords Protection against Pathological Thrombo-Inflammation'. Cells, 9 (11). pp. 1 - 18. ISSN: 2073-4409 Open Access Link

Journal article

Omura, S., Sato, F., Park, A-M., Fujita, M., Khadka, S., Nakamura, Y., et al. (2020) 'Bioinformatics Analysis of Gut Microbiota and CNS Transcriptome in Virus-Induced Acute Myelitis and Chronic Inflammatory Demyelination; Potential Association of Distinct Bacteria with CNS IgA upregulation'. Frontiers in Immunology Mucosal Immunity, 11. pp. 1 - 18. ISSN: 1664-3224 Open Access Link

Journal article

Boltersdorf, T., Ansari, J., Senchenkova, EY., Groeper, J., Pajonczyk, D., Vital, SA., et al. (2020) 'Targeting of Formyl Peptide Receptor 2 for in vivo imaging of acute vascular inflammation'. Theranostics, 10 (15). pp. 6599 - 6614. ISSN: 1838-7640 Open Access Link

Journal article

Boltersdorf, T., Ansari, J., Senchenkova, E., Jiang, L., White, AJP., Coogan, M., et al. (2019) 'Development, characterisation and in vitro evaluation of lanthanide-based FPR2/ALX-targeted imaging probes'. Dalton Transactions, 48 (44). pp. 16764 - 16775. ISSN: 1477-9226 Open Access Link

Journal article

Becker, F., Romero, E., Goetzmann, J., Hasselschwert, DL., Dray, B., Vanchiere, J., et al. (2019) 'Endogenous Specialized Proresolving Mediator Profiles in a Novel Experimental Model of Lymphatic Obstruction and Intestinal Inflammation in African Green Monkeys'. American Journal of Pathology, 189 (10). pp. 1953 - 1972. ISSN: 0002-9440

Journal article

Senchenkova, EY., Ansari, J., Becker, F., Vital, SA., Al-Yafeai, Z., Sparkenbaugh, EM., et al. (2019) 'Novel Role for the AnxA1-Fpr2/ALX Signaling Axis as a Key Regulator of Platelet Function to Promote Resolution of Inflammation'. Circulation, 140 (4). pp. 319 - 335. ISSN: 0009-7322 Open Access Link

Journal article

Becker, F., Gavins, FNE., Fontenot, J., Jordan, P., Yun, JY., Scott, R., et al. (2019) 'Dynamic gut microbiome changes following regional intestinal lymphatic obstruction in primates'. Pathophysiology, 26 (3-4). pp. 253 - 261. ISSN: 0928-4680 Open Access Link

Journal article

Ansari, J. and Gavins, FNE. (2019) 'Ischemia-Reperfusion Injury in Sickle Cell Disease: From Basics to Therapeutics'. The American Journal of Pathology, 189 (4). pp. 706 - 718. ISSN: 0002-9440 Open Access Link

Journal article

Barzegar, M., Kaur, G., Gavins, FNE., Wang, Y., Boyer, CJ. and Alexander, JS. (2019) 'Potential therapeutic roles of stem cells in ischemia-reperfusion injury'. Stem Cell Research, 37. pp. 1 - 15. ISSN: 1873-5061 Open Access Link

Journal article

Senchenkova, EY., Russell, J., Yildirim, A., Granger, DN. and Gavins, FNE. (2019) 'Novel Role of T Cells and IL-6 (Interleukin-6) in Angiotensin II–Induced Microvascular Dysfunction'. Hypertension, 73 (4). pp. 829 - 838. ISSN: 0194-911X Open Access Link

Journal article

Winny Yun, J., Steve Alexander, J. and Gavins, FNE. (2019) 'CNS lymphatics in health and disease', inLymphatic Structure and Function in Health and Disease. Elsevier. pp. 93 - 107. ISBN 13: 9780128156452.

Book chapter

Gavins, FNE. and Steve Alexander, J. (2019) 'Introduction/overview', inLymphatic Structure and Function in Health and Disease. Elsevier. pp. 1 - 4. ISBN 13: 9780128156452.

Book chapter

Gavins, FNE. and Steve Alexander, J. (2019) 'Lymphatic structure and function in health and disease'. Elsevier. ISSN 13: 9780128156452

Book

Al-Kofahi, M., Omura, S., Tsunoda, I., Sato, F., Becker, F., Gavins, FNE., et al. (2018) 'IL-1β reduces cardiac lymphatic muscle contraction via COX-2 and PGE2 induction: Potential role in myocarditis'. Biomedicine & Pharmacotherapy, 107 (November 2018). pp. 1591 - 1600. ISSN: 0753-3322

Journal article

Gillespie, S., Holloway, PM., Becker, F., Rauzi, F., Vital, SA., Taylor, KA., et al. (2018) 'The isothiocyanate sulforaphane modulates platelet function and protects against cerebral thrombotic dysfunction'. British Journal of Pharmacology, 175 (16). pp. 3333 - 3346. ISSN: 0007-1188

Journal article

Senchenkova, EY., Russell, J., Vital, SA., Yildirim, A., Orr, AW., Granger, DN. and et al. (2018) 'A critical role for both CD40 and VLA5 in angiotensin II–mediated thrombosis and inflammation'. The FASEB Journal, 32 (6). pp. 3448 - 3456. ISSN: 0892-6638 Open Access Link

Journal article

Smith, HK., Omura, S., Vital, SA., Becker, F., Senchenkova, EY., Kaur, G., et al. (2018) 'Metallothionein I as a direct link between therapeutic hematopoietic stem/progenitor cells and cerebral protection in stroke'. The FASEB Journal, 32 (5). pp. 2381 - 2394. ISSN: 0892-6638 Open Access Link

Journal article

Ansari, J., Kaur, G. and Gavins, F. (2018) 'Therapeutic Potential of Annexin A1 in Ischemia Reperfusion Injury'. International Journal of Molecular Sciences, 19 (4). pp. 1 - 19. ISSN: 1661-6596 Open Access Link

Journal article

Ansari, J., Moufarrej, YE., Pawlinski, R. and Gavins, FNE. (2018) 'Sickle cell disease: a malady beyond a hemoglobin defect in cerebrovascular disease'. Expert Review of Hematology, 11 (1). pp. 45 - 55. ISSN: 1747-4086

Journal article

Igbinedion, SO., Ansari, J., Vasikaran, A., Gavins, F., Jordan, P., Boktor, M. and et al. (2017) 'Non-celiac gluten sensitivity: All wheat attack is not celiac'. World Journal of Gastroenterology, 23 (40). pp. 7201 - 7210. ISSN: 1007-9327 Open Access Link

Journal article

Hughes, EL., Becker, F., Flower, RJ., Buckingham, JC. and Gavins, FNE. (2017) 'Mast cells mediate early neutrophil recruitment and exhibit anti-inflammatory properties via the formyl peptide receptor 2/lipoxin A4 receptor'. British Journal of Pharmacology, 174 (14). pp. 2393 - 2408. ISSN: 0007-1188 Open Access Link

Journal article

Becker, F., Holthoff, C., Anthoni, C., Rijcken, E., Alexander, JS., Gavins, FNE., et al. (2016) 'Downregulation of CX3CR1 ameliorates experimental colitis: evidence for CX3CL1-CX3CR1-mediated immune cell recruitment'. International Journal of Colorectal Disease, 32 (3). pp. 315 - 324. ISSN: 0179-1958

Journal article

Vital, SA. and Gavins, FNE. (2016) 'Surgical Approach for Middle Cerebral Artery Occlusion and Reperfusion Induced Stroke in Mice'. Journal of Visualized Experiments, 2016 (116). ISSN: 1940-087X

Journal article

Holloway, PM., Gillespie, S., Becker, F., Vital, SA., Nguyen, V., Alexander, JS., et al. (2016) 'Sulforaphane induces neurovascular protection against a systemic inflammatory challenge via both Nrf2-dependent and independent pathways'. Vascular Pharmacology, 85. pp. 29 - 38. ISSN: 1537-1891 Open Access Link

Journal article

Becker, F., Kurmaeva, E., Gavins, FNE., Stevenson, EV., Navratil, AR., Jin, L., et al. (2016) 'A Critical Role for Monocytes/Macrophages During Intestinal Inflammation-associated Lymphangiogenesis'. Inflammatory Bowel Diseases, 22 (6). pp. 1326 - 1345. ISSN: 1078-0998

Journal article

Vital, SA., Becker, F., Holloway, PM., Russell, J., Perretti, M., Granger, DN. and et al. (2016) 'Formyl-Peptide Receptor 2/3/Lipoxin A4 Receptor Regulates Neutrophil-Platelet Aggregation and Attenuates Cerebral Inflammation Impact for Therapy in Cardiovascular Disease'. Circulation, 133 (22). pp. 2169 - 2179. ISSN: 0009-7322 Open Access Link

Journal article

Holloway, PM. and Gavins, FNE. (2016) 'Modeling Ischemic Stroke in Vitro: Status Quo and Future Perspectives'. Stroke, 47 (2). pp. 561 - 569. ISSN: 0039-2499

Journal article

Gavins, FNE. (2016) 'Sepsis', inVascular Responses to Pathogens. Elsevier. pp. 1 - 9. ISBN 13: 9780128010785.

Book chapter

Gavins, FNE. and Stokes, KY. (2016) 'Overview'. Elsevier. ISSN 13: 9780128010785

Book

Gavins, FNE. and Stokes, KY. (2015) 'Vascular Responses to Pathogens'. Elsevier. ISSN 13: 9780128010785

Book

Al-Kofahi, M., Becker, F., Gavins, FNE., Woolard, MD., Tsunoda, I., Wang, Y., et al. (2015) 'IL-1β reduces tonic contraction of mesenteric lymphatic muscle cells, with the involvement of cycloxygenase-2 and prostaglandin E2'. British Journal of Pharmacology, 172 (16). pp. 4038 - 4051. ISSN: 0007-1188

Journal article

Smith, HK., Russell, JM., Granger, DN. and Gavins, FNE. (2015) 'Critical differences between two classical surgical approaches for middle cerebral artery occlusion-induced stroke in mice'. Journal of Neuroscience Methods, 249. pp. 99 - 105. ISSN: 0165-0270

Journal article

Buss, NAPS., Gavins, FNE., Cover, PO., Terron, A. and Buckingham, JC. (2015) 'Targeting the annexin 1-formyl peptide receptor 2/ALX pathway affords protection against bacterial LPS-induced pathologic changes in the murine adrenal cortex'. FASEB Journal, 29 (7). pp. 2930 - 2942. ISSN: 0892-6638

Journal article

Holloway, PM., Durrenberger, PF., Trutschl, M., Cvek, U., Cooper, D., Orr, AW., et al. (2015) 'Both MC 1 and MC 3 Receptors Provide Protection From Cerebral Ischemia-Reperfusion–Induced Neutrophil Recruitment'. Arteriosclerosis, Thrombosis, and Vascular Biology, 35 (9). pp. 1936 - 1944. ISSN: 1079-5642

Journal article

Becker, F., Holthoff, C., Anthoni, C., Alexander, JS., Gavins, FN., Senninger, N. and et al. (2015) 'Mo1696 CX3CL1-CX3CR1 in Acute Colitis: Evidence for Chemokine-Mediated Leukocyte Recruitment'. Gastroenterology, 148 (4). pp. S - 688. ISSN: 0016-5085

Journal article

Smith, HK., Gil, CD., Oliani, SM. and Gavins, FNE. (2015) 'Targeting formyl peptide receptor 2 reduces leukocyte‐endothelial interactions in a murine model of stroke'. The FASEB Journal, 29 (5). pp. 2161 - 2171. ISSN: 0892-6638

Journal article

Stasiuk, GJ., Holloway, PM., Rivas, C., Trigg, W., Luthra, SK., Morisson Iveson, V., et al. (2015) '99mTc SPECT imaging agent based on cFLFLFK for the detection of FPR1 in inflammation'. Dalton Transactions, 44 (11). pp. 4986 - 4993. ISSN: 1477-9226

Journal article

Gavins, FNE. and Smith, HK. (2015) 'Cell tracking technologies for acute ischemic brain injury'. Journal of Cerebral Blood Flow and Metabolism, 35 (7). pp. 1090 - 1099. ISSN: 0271-678X

Journal article

Bilal Iqbal, M., Johns, M., Cao, J., Liu, Y., Yu, SC., Hyde, GD., et al. (2014) 'PARP-14 combines with tristetraprolin in the selective posttranscriptional control of macrophage tissue factor expression'. Blood, 124 (24). pp. 3646 - 3655. ISSN: 0006-4971

Journal article

Amsellem, V., Dryden, NH., Martinelli, R., Gavins, F., Almagro, LO., Birdsey, GM., et al. (2014) 'ICAM-2 regulates vascular permeability and N-cadherin localization through ezrin-radixin-moesin (ERM) proteins and Rac-1 signalling'. Cell Communication and Signaling, 12 (1). pp. 12. ISSN: 1478-811X Open Access Link

Journal article

Hughes, EL., Cover, PO., Buckingham, JC. and Gavins, FNE. (2013) 'Role and interactions of annexin A1 and oestrogens in the manifestation of sexual dimorphisms in cerebral and systemic inflammation'. British Journal of Pharmacology, 169 (3). pp. 539 - 553. ISSN: 0007-1188

Journal article

Gillespie, S. and Gavins, FNE. (2013) 'Phytochemicals: Countering risk factors and pathological responses associated with ischaemia reperfusion injury'. Pharmacology and Therapeutics, 138 (1). pp. 38 - 45. ISSN: 0163-7258

Journal article

Stasiuk, GJ., Smith, H., Wylezinska-Arridge, M., Tremoleda, JL., Trigg, W., Kaur Luthra, S., et al. (2013) 'Gd3+ cFLFLFK conjugate for MRI: A targeted contrast agent for FPR1 in inflammation'. Chemical Communications, 49 (6). pp. 564 - 566. ISSN: 1359-7345

Journal article

Gavins, FNE., Hughes, EL., Buss, NAPS., Holloway, PM., Getting, SJ. and Buckingham, JC. (2012) 'Leukocyte recruitment in the brain in sepsis: Involvement of the annexin 1-FPR2/ALX anti-inflammatory system'. FASEB Journal, 26 (12). pp. 4977 - 4989. ISSN: 0892-6638

Journal article

Gavins, FNE. and Hickey, MJ. (2012) 'Annexin A1 and the regulation of innate and adaptive immunity'. Frontiers in Immunology, 3 (NOV). pp. 354. ISSN: 1664-3224 Open Access Link

Journal article

Gavins, FNE. (2012) 'Intravital microscopy: New insights into cellular interactions'. Current Opinion in Pharmacology, 12 (5). pp. 601 - 607. ISSN: 1471-4892

Journal article