Precision to the very end: what happens when two replication forks converge during termination?
Funder: Biotechnology and Biological Sciences Research CouncilDuration: September 2016 - August 2019
Collaborative grant with York University
People
| Name | Telephone | Office | ||
|---|---|---|---|---|
|
Dr Christian Rudolph Reader (Principal investigator)
T: +44 (0)1895 265372
E: christian.rudolph@brunel.ac.uk |
+44 (0)1895 265372 | christian.rudolph@brunel.ac.uk | Heinz Wolff 112 |
Outputs
Goodall, DJ., Warecka, D., Hawkins, M. and Rudolph, CJ. (2023) 'Interplay between chromosomal architecture and termination of DNA replication in bacteria'. Frontiers in Microbiology, 14. pp. 1 - 19. ISSN: 1664-302X Open Access Link
Jameson, KH., Rudolph, C. and Hawkins, M. (2021) 'Termination of DNA replication at Tus-ter barriers results in under-replication of template DNA'. Journal of Biological Chemistry, 297 (6). pp. 1 - 14. ISSN: 0021-9258 Open Access Link
Goodall, DJ., Jameson, KH., Hawkins, M. and Rudolph, CJ. (2021) 'A fork trap in the chromosomal termination area is highly conserved across all Escherichia coli phylogenetic groups'. International Journal of Molecular Sciences, 22 (15). pp. 1 - 24. ISSN: 1661-6596 Open Access Link
Hawkins, M., Dimude, JU., Howard, JAL., Smith, AJ., Dillingham, MS., Savery, NJ., et al. (2019) 'Direct removal of RNA polymerase barriers to replication by accessory replicative helicases'. Nucleic Acids Research, 47 (10). pp. 5100 - 5113. ISSN: 0305-1048 Open Access Link
Rudolph, C., Corocher, T-A., Grainge, I. and Duggin, IG. (2019) 'Termination of DNA Replication in Prokaryotes', inEncyclopedia of Life Sciences. Wiley [Imprint] Hoboken. pp. 1 - 15. ISBN 10: 047001590X. ISBN 13: 9780470016176. Open Access Link
Midgley-Smith, S., Dimude, J. and Rudolph, C. (2018) 'A role for 3’ exonucleases at the final stages of chromosome duplication in Escherichia coli'. Nucleic Acids Research, 47 (4). pp. 1847 - 1860. ISSN: 0305-1048 Open Access Link
Dimude, JU., Midgley-Smith, SL. and Rudolph, CJ. (2018) 'Replication-transcription conflicts trigger extensive DNA degradation in Escherichia coli cells lacking RecBCD'. Mutation Research/DNA Repair, 70. pp. 37 - 48. ISSN: 0921-8777 Open Access Link
Dimude, JU., Stein, M., Andrzejewska, EE., Khalifa, MS., Gajdosova, A., Retkute, R., et al. (2018) 'Origins Left, Right, and Centre: Increasing the Number of Initiation Sites in the Escherichia coli Chromosome'. Genes, 9 (8). pp. 1 - 21. ISSN: 2073-4425 Open Access Link
Midgley-Smith, SL., Dimude, JU., Taylor, T., Forrester, NM., Upton, AL., Lloyd, RG. and et al. (2018) 'Chromosomal over-replication in Escherichia coli recG cells is triggered by replication fork fusion and amplified if replichore symmetry is disturbed'. Nucleic Acids Research, 46 (15). pp. 7701 - 7715. ISSN: 0305-1048 Open Access Link