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Professor Alex Blakemore
Professor in Human Genomics

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Almansoori, S., Alsters, SI., Yiorkas, AM., Nor Hashim, NA., Walters, RG., Chahal, HS., et al. (2024) 'Oligogenic inheritance in severe adult obesity'. International Journal of Obesity. ISSN: 0307-0565

Journal article

Zagkos, L., Drenos, F., Emmett, P., Blakemore, AI., Nordström, T., Hurtig, T., et al. (2023) 'Associations of adolescents’ diet and meal patterns with school performance in the Northern Finland Birth Cohort 1986: A Mendelian randomisation study'. Appetite, 190. pp. 1 - 10. ISSN: 0195-6663 Open Access Link

Journal article

Handley, D., Almansoori, S., Sato, MS., Amin, H., Alsters, S., Chahal, H., et al. (2023) 'Rare variants of the glucagon-like peptide-1 receptor (GLP1R) gene are overrepresented in a severe obesity cohort and associated with type 2 diabetes in the UK Biobank'. .

Journal article

Ramzi, NH., Auvinen, J., Veijola, J., Miettunen, J., Ala-Mursula, L., Sebert, S., et al. (2023) 'Depression mediates the relationship between alexithymia and obesity in the Northern Finland Birth Cohort 1966 (NFBC1966)'. Journal of Affective Disorders, 331. pp. 1 - 7. ISSN: 0165-0327 Open Access Link

Journal article

Amin, HA., Kaewsri, P., Yiorkas, AM., Cooke, H., Blakemore, AI. and Drenos, F. (2022) 'Mendelian randomisation analyses of UK Biobank and published data suggest that increased adiposity lowers risk of breast and prostate cancer'. Scientific Reports, 12 (1). pp. 1 - 10. ISSN: 2045-2322 Open Access Link

Journal article

Amin, HA., Cordell, HJ., Martin-Ruiz, C., Robinson, L., Kirkwood, T., Blakemore, AI. and et al. (2022) 'No Evidence That Genetic Variation at the Klotho Locus Is Associated With Longevity in Caucasians from the Newcastle 85+ Study and the UK Biobank'. The Journals of Gerontology: Series A, 77 (3). pp. 457 - 461. ISSN: 1079-5006 Open Access Link

Journal article

Sen, P., Adewusi, D., Blakemore, A. and Kumari, V. (2021) 'How do lipids influence risk of violence, self-harm and suicidality in people with psychosis? A systematic review'. Australian and New Zealand Journal of Psychiatry, 56 (5). pp. 451 - 488. ISSN: 0004-8674 Open Access Link

Journal article

Alkaf, BA., Parkinson, JP., Thomas, LT., Blakemore, AB., Jarvelin, MJ. and Lessan, NL. (2021) 'Contribution of obesity and physical inactivity to the increased type 2 diabetes risk in Emiratis'. WILEY. ISSN: 0742-3071

Conference paper

Kenkre, JS., Ahmed, AR., Purkayastha, S., Malallah, K., Bloom, S., Blakemore, AI., et al. (2021) 'Who will benefit from bariatric surgery for diabetes? A protocol for an observational cohort study'. BMJ Open, 11 (2). pp. 1 - 8. ISSN: 2044-6055 Open Access Link

Journal article

Surendran, P., Feofanova, EV., Lahrouchi, N., Ntalla, I., Karthikeyan, S., Cook, J., et al. (2020) 'Discovery of rare variants associated with blood pressure regulation through meta-analysis of 1.3 million individuals'. Nature Genetics, 52 (12). pp. 1314 - 1332. ISSN: 1061-4036 Open Access Link

Journal article

O'Kane, M., Parretti, HM., Pinkney, J., Welbourn, R., Hughes, CA., Mok, J., et al. (2020) 'British Obesity and Metabolic Surgery Society Guidelines on perioperative and postoperative biochemical monitoring and micronutrient replacement for patients undergoing bariatric surgery—2020 update'. Obesity Reviews, 21 (11). pp. 1 - 23. ISSN: 1467-7881 Open Access Link

Journal article

Sato, MS., Kyriakopoulos, M., James, A., Marwedel, S., Borsay, C., Gutierrez, AA., et al. (2020) 'Hemizygous mutations in L1CAM in two unrelated male probands with childhood onset psychosis'. Psychiatric Genetics, 30 (3). pp. 73 - 82. ISSN: 0955-8829 Open Access Link

Journal article

Li, C., Stoma, S., Lotta, LA., Warner, S., Albrecht, E., Allione, A., et al. (2020) 'Genome-wide Association Analysis in Humans Links Nucleotide Metabolism to Leukocyte Telomere Length'. American Journal of Human Genetics, 106 (3). pp. 389 - 404. ISSN: 0002-9297 Open Access Link

Journal article

Murphy, J., Uttamlal, T., Schmidtke, KA., Vlaev, I., Taylor, D., Ahmad, M., et al. (2020) 'Tracking physical activity using smart phone apps: assessing the ability of a current app and systematically collecting patient recommendations for future development'. BMC Medical Informatics and Decision Making, 20 (17). pp. 1 - 11. ISSN: 1472-6947 Open Access Link

Journal article

Cooiman, MI., Kleinendorst, L., Aarts, EO., Janssen, IMC., van Amstel, HKP., Blakemore, AI., et al. (2020) 'Genetic Obesity and Bariatric Surgery Outcome in 1014 Patients with Morbid Obesity'. Obesity Surgery, 30 (2). pp. 470 - 477. ISSN: 0960-8923

Journal article

Wilson, MSJ., Knight, S., Vaughan‐Shaw, P., Blakemore, AI., O'Kane, M., Boyle, C., et al. (2019) 'A modified AUGIS Delphi process to establish research priorities in bariatric and metabolic surgery'. Clinical Obesity, 2019 (e12344). pp. 1 - 5. ISSN: 1758-8103 Open Access Link

Journal article

Ng, N., Willems, SM., Fernandez, J., Fine, RS., Wheeler, E., Wessel, J., et al. (2019) 'Tissue-Specific Alteration of Metabolic Pathways Influences Glycemic Regulation'. Cell, 0 ((under consideration)). ISSN: 0092-8674 Open Access Link

Journal article

Ramzi, NH., Yiorkas, A., Sebert, S., Keinanen-Kiukaanniemi, S., Ala-Mursulu, L., Jokelainen, J., et al. (2018) 'Relationship between BMI and emotion-handling capacity in an adult Finnish population: the Northern Finland Birth Cohort 1966'. PLoS ONE, 13 (9). pp. 1 - 11. ISSN: 1932-6203 Open Access Link

Journal article

Macare, C., Ducci, F., Zhang, Y., Ruggeri, B., Jia, T., Kaakinen, M., et al. (2018) 'A neurobiological pathway to smoking in adolescence: TTC12-ANKK1-DRD2 variants and reward response'. European Neuropsychopharmacology, 28 (10). pp. 1103 - 1114. ISSN: 0924-977X Open Access Link

Journal article

Schierding, W., Antony, J., Karhunen, V., Vääräsmäki, M., Franks, S., Elliott, P., et al. (2018) 'GWAS on prolonged gestation (post-term birth): Analysis of successive finnish birth cohorts'. Journal of Medical Genetics, 55 (1). pp. 55 - 63. ISSN: 0022-2593

Journal article

Kraja, AT., Cook, JP., Warren, HR., Surendran, P., Liu, C., Evangelou, E., et al. (2017) 'New Blood Pressure–Associated Loci Identified in Meta-Analyses of 475 000 IndividualsCLINICAL PERSPECTIVE'. Circulation: Cardiovascular Genetics, 10 (5). pp. e001778 - e001778. ISSN: 1942-325X Open Access Link

Journal article

Fiamoncini, J., Yiorkas, AM., Gedrich, K., Rundle, M., Alsters, SI., Roeselers, G., et al. (2017) 'Determinants of postprandial plasma bile acid kinetics in human volunteers'. American Journal of Physiology - Gastrointestinal and Liver Physiology, 313 (4). pp. G300 - G312. ISSN: 0193-1857 Open Access Link

Journal article

Williams, DM., Buxton, JL., Kantomaa, MT., Tammelin, TH., Blakemore, AIF. and Järvelin, MR. (2017) 'Associations of leukocyte telomere length with aerobic and muscular fitness in Young adults'. American Journal of Epidemiology, 185 (7). pp. 529 - 537. ISSN: 0002-9262 Open Access Link

Journal article

Tharakan, G., Scott, R., Szepietowski, O., Miras, AD., Blakemore, AI., Purkayastha, S., et al. (2017) 'Limitations of the DiaRem Score in Predicting Remission of Diabetes Following Roux-En-Y Gastric Bypass (RYGB) in an ethnically Diverse Population from a Single Institution in the UK'. Obesity Surgery, 27 (3). pp. 782 - 786. ISSN: 0960-8923 Open Access Link

Journal article

Surendran, P., Drenos, F., Young, R., Warren, H., Cook, JP., Manning, AK., et al. (2016) 'Trans-ancestry meta-analyses identify rare and common variants associated with blood pressure and hypertension'. NATURE GENETICS, 48 (10). pp. 1151 - 1161. ISSN: 1061-4036 Open Access Link

Journal article

Ruffmann, C., Calboli, FCF., Bravi, I., Gveric, D., Curry, LK., de Smith, A., et al. (2016) 'Cortical Lewy bodies and Aβ burden are associated with prevalence and timing of dementia in Lewy body diseases'. Neuropathology and Applied Neurobiology, 42 (5). pp. 436 - 450. ISSN: 0305-1846

Journal article

Kanoni, S., Masca, NGD., Stirrups, KE., Varga, TV., Warren, HR., Scott, RA., et al. (2016) 'Analysis with the exome array identifies multiple new independent variants in lipid loci'. Human Molecular Genetics, 25 (18). pp. ddw227 - ddw227. ISSN: 0964-6906 Open Access Link

Journal article

O'Kane, M., Parretti, HM., Hughes, CA., Sharma, M., Woodcock, S., Puplampu, T., et al. (2016) 'Guidelines for the follow-up of patients undergoing bariatric surgery'. Clinical Obesity, 6 (3). pp. 210 - 224. ISSN: 1758-8103

Journal article

Malietzis, G., Lee, GH., Al-Hassi, HO., Bernardo, D., Blakemore, AIF., Kennedy, RH., et al. (2016) 'Body composition of the host influences dendritic cell phenotype in patients treated for colorectal cancer'. Tumor Biology, 37 (8). pp. 1 - 6. ISSN: 1010-4283

Journal article

Williams, DM., Palaniswamy, S., Sebert, S., Buxton, JL., Blakemore, AIF., Hyppoenen, E. and et al. (2016) '25-Hydroxyvitamin D Concentration and Leukocyte Telomere Length in Young Adults: Findings From the Northern Finland Birth Cohort 1966'. American Journal of Epidemiology, 183 (3). pp. 191 - 198. ISSN: 0002-9262 Open Access Link

Journal article

Felix, JF., Bradfield, JP., Monnereau, C., van der Valk, RJP., Stergiakouli, E., Chesi, A., et al. (2016) 'Genome-wide association analysis identifies three new susceptibility loci for childhood body mass index'. HUMAN MOLECULAR GENETICS, 25 (2). pp. 389 - 403. ISSN: 0964-6906

Journal article

Taylor, D., Murphy, J., Ahmad, M., Purkayastha, S., Scholtz, S., Ramezani, R., et al. (2016) 'Quantified-Self for Obesity: Physical Activity Behaviour Sensing to Improve Health Outcomes.'. Stud Health Technol Inform, 220. pp. 414 - 416. ISSN: 0926-9630

Journal article

Malietzis, G., Lee, GH., Bernardo, D., Blakemore, AIF., Knight, SC., Moorghen, M., et al. (2015) 'The prognostic significance and relationship with body composition of CCR7-positive cells in colorectal cancer'. Journal of Surgical Oncology, 112 (1). pp. 86 - 92. ISSN: 0022-4790

Journal article

Alsters, SIM., Goldstone, AP., Buxton, JL., Zekavati, A., Sosinsky, A., Yiorkas, AM., et al. (2015) 'Truncating Homozygous Mutation of Carboxypeptidase E (CPE) in a Morbidly Obese Female with Type 2 Diabetes Mellitus, Intellectual Disability and Hypogonadotrophic Hypogonadism'. PLOS ONE, 10 (6). pp. e0131417 - e0131417. ISSN: 1932-6203 Open Access Link

Journal article

Noseda, M., Harada, M., McSweeney, S., Leja, T., Belian, E., Stuckey, DJ., et al. (2015) 'PDGFR alpha demarcates the cardiogenic clonogenic Sca1(+) stem/progenitor cell in adult murine myocardium'. NATURE COMMUNICATIONS, 6 (1). pp. 6930. ISSN: 2041-1723 Open Access Link

Journal article

Stathopoulou, MG., Petrelis, AM., Buxton, JL., Froguel, P., Blakemore, AIF. and Visvikis-Siest, S. (2015) 'Genetic determinants of leucocyte telomere length in children: A neglected and challenging field'. Paediatric and Perinatal Epidemiology, 29 (2). pp. 146 - 150. ISSN: 0269-5022

Journal article

van der Valk, RJ., Kreiner-Møller, E., Kooijman, MN., Guxens, M., Stergiakouli, E., Sääf, A., et al. (2015) 'A novel common variant in DCST2 is associated with length in early life and height in adulthood.'. Human Molecular Genetics, 24 (4). pp. 1155 - 1168. ISSN: 0964-6906 Open Access Link

Journal article

Buxton, JL., Das, S., Rodriguez, A., Kaakinen, M., Alves, AC., Sebert, S., et al. (2014) 'Multiple Measures of Adiposity Are Associated with Mean Leukocyte Telomere Length in the Northern Finland Birth Cohort 1966'. PLOS ONE, 9 (6). pp. e99133 - e99133. ISSN: 1932-6203 Open Access Link

Journal article

Martins-Taylor, K., Hsiao, JS., Chen, PF., Glatt-Deeley, H., De Smith, AJ., Blakemore, AIF., et al. (2014) 'Imprinted expression of UBE3A in non-neuronal cells from a Prader-willi syndrome patient with an atypical deletion'. Human Molecular Genetics, 23 (9). pp. 2364 - 2373. ISSN: 0964-6906

Journal article

Albrecht, E., Sillanpää, E., Karrasch, S., Alves, AC., Codd, V., Hovatta, I., et al. (2014) 'Telomere length in circulating leukocytes is associated with lung function and disease'. European Respiratory Journal, 43 (4). pp. 983 - 992. ISSN: 0903-1936

Journal article

Blakemore, AIF. and Buxton, JL. (2014) 'Obesity, genetic risk, and environment'. BMJ (Online), 348 (mar19 3). pp. g1900 - g1900. ISSN: 1756-1833

Journal article

Ala-Mursula, L., Buxton, JL., Ek, E., Koiranen, M., Taanila, A., Blakemore, AIF. and et al. (2013) 'Long-Term Unemployment Is Associated with Short Telomeres in 31-Year-Old Men: An Observational Study in the Northern Finland Birth Cohort 1966'. PLOS ONE, 8 (11). pp. e80094 - e80094. ISSN: 1932-6203 Open Access Link

Journal article

Evans, DM., Brion, MJA., Paternoster, L., Kemp, JP., McMahon, G., Munafò, M., et al. (2013) 'Mining the Human Phenome Using Allelic Scores That Index Biological Intermediates'. PLoS Genetics, 9 (10). pp. e1003919 - e1003919. ISSN: 1553-7404

Journal article

Dorajoo, R., Li, R., Ikram, MK., Liu, J., Froguel, P., Lee, J., et al. (2013) 'Are C-Reactive Protein Associated Genetic Variants Associated with Serum Levels and Retinal Markers of Microvascular Pathology in Asian Populations from Singapore?'. PLOS ONE, 8 (7). pp. e67650 - e67650. ISSN: 1932-6203 Open Access Link

Journal article

Al-Hassi, HO., Bernardo, D., Murugananthan, AU., Mann, ER., English, NR., Jones, A., et al. (2013) 'A mechanistic role for leptin in human dendritic cell migration: differences between ileum and colon in health and Crohn's disease'. MUCOSAL IMMUNOLOGY, 6 (4). pp. 751 - 761. ISSN: 1933-0219 Open Access Link

Journal article

Codd, V., Nelson, CP., Albrecht, E., Mangino, M., Deelen, J., Buxton, JL., et al. (2013) 'Identification of seven loci affecting mean telomere length and their association with disease'. Nature Genetics, 45 (4). pp. 422 - 427. ISSN: 1061-4036

Journal article

Walters, RG., Coin, LJM., Ruokonen, A., de Smith, AJ., Moustafa, JSE-S., Jacquemont, S., et al. (2013) 'Rare Genomic Structural Variants in Complex Disease: Lessons from the Replication of Associations with Obesity'. PLOS ONE, 8 (3). pp. e58048 - e58048. ISSN: 1932-6203 Open Access Link

Journal article

Horikoshi, M., Yaghootkar, H., Mook-Kanamori, DO., Sovio, U., Taal, HR., Hennig, BJ., et al. (2013) 'New loci associated with birth weight identify genetic links between intrauterine growth and adult height and metabolism'. NATURE GENETICS, 45 (1). pp. 76 - U115. ISSN: 1061-4036 Open Access Link

Journal article

Noseda, M., De Smith, AJ., Leia, T., Rao, PH., Paiva, MSA., Al-Beidh, F., et al. (2012) 'The Cdkn2a/2b Tumour Suppressor Locus is a Hot Spot for Genome Instability in Mouse Cardiac Progenitor Cells'. CIRCULATION, 126 (21). pp. S59 - S59. ISSN: 0009-7322

Journal article
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