CenGEM
Coutelle, C., Themis, M., Waddington, S., Gregory, L., Nivsarkar, M., Buckley, S., et al. (2003) 'The Hopes and Fears of In Utero Gene Therapy for Genetic Disease—A Review'.Symposium on From Genetics to Implantation and Early Fetal Development in Infertile Couples. MILAN, ITALY. Elsevier BV. pp. S114 - S121. ISSN: 0143-4004
Tosi, S., Hughes, J., Scherer, SW., Nakabayashi, K., Harbott, J., Haas, OA., et al. (2003) 'Heterogeneity of the 7q36 breakpoints in the t(7;12) involving ETV6 in infant leukemia'. Genes, Chromosomes and Cancer, 38 (2). pp. 191 - 200. ISSN: 1045-2257
Régnier, V., Novelli, J., Fukagawa, T., Vagnarelli, P. and Brown, W. (2003) 'Characterization of chicken CENP-A and comparative sequence analysis of vertebrate centromere-specific histone H3-like proteins'. Gene, 316 (1-2). pp. 39 - 46. ISSN: 0378-1119
Themis, M., May, D., Coutelle, C. and Newbold, RF. (2003) 'Mutational effects of retrovirus insertion on the genome of V79 cells by an attenuated retrovirus vector: Implications for gene therapy'. Gene Therapy, 10 (19). pp. 1703 - 1711. ISSN: 0969-7128
Selden, C., Casbard, A., Themis, M. and Hodgson, HJF. (2003) 'Characterization of Long-Term Survival of Syngeneic Hepatocytes in Rat Peritoneum'. Cell Transplantation, 12 (6). pp. 569 - 578. ISSN: 0963-6897
Kibe, T. (2003) 'Fission yeast Rhp51 is required for the maintenance of telomere structure in the absence of the Ku heterodimer'. Nucleic Acids Research, 31 (17). pp. 5054 - 5063. ISSN: 0305-1048
Ueno, M., Nakazaki, T., Akamatsu, Y., Watanabe, K., Tomita, K., Lindsay, HD., et al. (2003) 'Molecular Characterization of the Schizosaccharomyces pombe nbs1+ Gene Involved in DNA Repair and Telomere Maintenance'. Molecular and Cellular Biology, 23 (18). pp. 6553 - 6563. ISSN: 0270-7306
Waddington, SN., Mitrophanous, KA., Ellard, FM., Buckley, SM., Nivsarkar, M., Lawrence, L., et al. (2003) 'Long-term transgene expression by administration of a lentivirus-based vector to the fetal circulation of immuno-competent mice'. Gene Therapy, 10 (15). pp. 1234 - 1240. ISSN: 0969-7128
Hudson, DF., Vagnarelli, P., Gassmann, R. and Earnshaw, WC. (2003) 'Condensin Is Required for Nonhistone Protein Assembly and Structural Integrity of Vertebrate Mitotic Chromosomes'. Developmental Cell, 5 (2). pp. 323 - 336. ISSN: 1534-5807
Tomita, K., Matsuura, A., Caspari, T., Carr, AM., Akamatsu, Y., Iwasaki, H., et al. (2003) 'Competition between the Rad50 Complex and the Ku Heterodimer Reveals a Role for Exo1 in Processing Double-Strand Breaks but Not Telomeres'. Molecular and Cellular Biology, 23 (15). pp. 5186 - 5197. ISSN: 0270-7306
Chastain-Moore, AM., Roberts, T., Trott, DA., Newbold, RF. and Ornelles, DA. (2003) 'An activity associated with human chromosome 21 permits nuclear colocalization of the adenovirus E1B-55K and E4orf6 proteins and promotes viral late gene expression'. Journal of Virology, 77 (14). pp. 8087 - 8098. ISSN: 0022-538X Open Access Link
Azzouz, M., Le, TN., Waddington, S., Walmsley, L., Monani, U., Wilkes, FJ., et al. (2003) 'Lentiviral vector-mediated gene therapy for a mouse model of spinal muscular atrophy'.6th Annual Meeting of the American-Society-of-Gene-Therapy. WASHINGTON, D.C. 4 - 8 June. ACADEMIC PRESS INC ELSEVIER SCIENCE. pp. S248 - S248. ISSN: 1525-0016
Waddington, SN., Buckley, SMK., Cook, T., Gregory, L., Rahim, A., Nivsarkar, M., et al. (2003) 'Fetal gene delivery using first and second generation Sendai virus'.6th Annual Meeting of the American-Society-of-Gene-Therapy. WASHINGTON, D.C. 4 - 8 June. ACADEMIC PRESS INC ELSEVIER SCIENCE. pp. S4 - S4. ISSN: 1525-0016
Buckley, SMK., Waddington, SN., Jezzard, S., Themis, M., Colledge, WH. and Coutelle, C. (2003) 'Intra-amniotic application of CFTR-expressing adenovirus does not reverse cystic fibrosis phenotype in inbred Cftr-knockout mice'.6th Annual Meeting of the American-Society-of-Gene-Therapy. WASHINGTON, D.C. 4 - 8 June. ACADEMIC PRESS INC ELSEVIER SCIENCE. pp. S200 - S200. ISSN: 1525-0016
Gregory, LG., Peebles, D., David, A., Themis, M., Waddington, SN., Knapton, HJ., et al. (2003) 'Widespread and efficient adenovirus-mediated gene transfer to the airways by DEAE dextran and sodium caprate in adult mice and fetal sheep after minimally invasive tracheal application'.6th Annual Meeting of the American-Society-of-Gene-Therapy. WASHINGTON, D.C. 4 - 8 June. NATURE PUBLISHING GROUP. pp. S142 - S143. ISSN: 1525-0016
Themis, M., Waddington, S., Holder, M., Buckley, S., Mitrophanos, K., Bigger, B., et al. (2003) 'Highly efficient and comprehensive gene transfer to all muscle groups necessary for the potential treatment of Duchenne/Becker muscular dystrophies following in utero delivery of a lentivirus vector in immuno-competent mice'.6th Annual Meeting of the American-Society-of-Gene-Therapy. WASHINGTON, D.C. 4 - 8 June. ACADEMIC PRESS INC ELSEVIER SCIENCE. pp. S320 - S320. ISSN: 1525-0016
Ono, Y., Tomita, K., Matsuura, A., Nakagawa, T., Masukata, H., Uritani, M., et al. (2003) 'A novel allele of fission yeast radii that causes defects in DNA repair and telomere length regulation'. KURRI Progress Report. pp. 117. ISSN: 0919-1038
David, A., Cook, T., Waddington, S., Peebles, D., Nivsarkar, M., Knapton, H., et al. (2003) 'Ultrasound-Guided Percutaneous Delivery of Adenoviral Vectors Encoding theβ-Galactosidase and Human Factor IX Genes to Early Gestation Fetal SheepIn Utero'. Human Gene Therapy, 14 (4). pp. 353 - 364. ISSN: 1043-0342
Randeva, H. (2003) 'Circadian rhythmicity of salivary leptin in healthy subjects'. Molecular Genetics and Metabolism, 78 (3). pp. 229 - 235. ISSN: 1096-7192
Tang, S., Bremner, P., Kortenkamp, A., Schlage, C., Gray, AI., Gibbons, S. and et al. (2003) 'Biflavonoids with Cytotoxic and Antibacterial Activity fromOchna macrocalyx'. Planta Medica, 69 (3). pp. 247 - 253. ISSN: 0032-0943
Anderson, RM., Marsden, SJ., Paice, SJ., Bristow, AE., Kadhim, MA., Griffin, CS. and et al. (2003) 'ERRATUM'. Radiation Research, 159 (3). pp. 437 - 437. ISSN: 0033-7587
Waddington, SN., Buckley, SMK., Nivsarkar, M., Jezzard, S., Schneider, H., Dahse, T., et al. (2003) 'In utero gene transfer of human factor IX to fetal mice can induce postnatal tolerance of the exogenous clotting factor'. BLOOD, 101 (4). pp. 1359 - 1366. ISSN: 0006-4971
Morrison, C., Vagnarelli, P., Sonoda, E., Takeda, S. and Earnshaw, WC. (2003) 'Sister chromatid cohesion and genome stability in vertebrate cells'. Biochem Soc Trans, 31 (Pt 1). pp. 263 - 265. ISSN: 0300-5127
Lopes, S. (2003) 'Epigenetic modifications in an imprinting cluster are controlled by a hierarchy of DMRs suggesting long-range chromatin interactions'. Human Molecular Genetics, 12 (3). pp. 295 - 305. ISSN: 0964-6906
Harvey, AJ. and Crompton, MR. (2003) 'Use of RNA interference to validate Brk as a novel therapeutic target in breast cancer: Brk promotes breast carcinoma cell proliferation'. Oncogene, 22 (32). pp. 5006 - 5010. ISSN: 0950-9232
David, AL., Peebles, DM., Gregory, L., Themis, M., Cook, T., Coutelle, C. and et al. (2003) 'Percutaneous Ultrasound-Guided Injection of the Trachea in Fetal Sheep: A Novel Technique to Target the Fetal Airways'. Fetal Diagnosis and Therapy, 18 (5). pp. 385 - 390. ISSN: 1015-3837
Gregory, LG., Harbottle, RP., Lawrence, L., Knapton, HJ., Themis, M. and Coutelle, C. (2003) 'Enhancement of adenovirus-mediated gene transfer to the airways by DEAE dextran and sodium caprate in vivo'. Molecular Therapy, 7 (1). pp. 19 - 26. ISSN: 1525-0016
Selden, C., Casbard, A., Themis, M. and Hodgson, HJF. (2003) 'Characterization of long-term survival of syngeneic hepatocytes in rat peritoneum'. Cell Transplantation, 12 (6). pp. 569 - 578. ISSN: 1555-3892
Bessant, DAR., Holder, GE., Fitzke, FW., Payne, AM., Bhattacharya, SS. and Bird, AC. (2003) 'Phenotype of retinitis pigmentosa associated with the Ser50Thr mutation in the NRL gene'. Archives of Ophthalmology, 121 (6). pp. 793 - 802. ISSN: 0003-9950
Anderson, RM., Marsden, SJ., Paice, SJ., Bristow, AE., Kadhim, MA., Griffin, CS. and et al. (2003) 'Transmissible and non-transmissible complex chromosome aberrations characterised by three-color and mFISH define a biomarker of exposure to high-LET α particles'. Radiation Research, 159 (1). pp. 40 - 48. ISSN: 0033-7587
Scherer, SW., Cheung, J., MacDonald, JR., Osborne, LR., Nakabayashi, K., Herbrick, JA., et al. (2003) 'Human chromosome 7: DNA sequence and biology'. Science, 300 (5620). pp. 767 - 772. ISSN: 0036-8075
KARTERIS., Goumenou, A., Hillhouse, E.W. and Koumantakis, E. (2003) 'Reduced expression of corticotropin-releasing hormone receptor type-1? in human preeclamptic and growth-restricted placentas'. Journal of Clinical Endocrinology & Metabolism, 88 (1). pp. 363 - 370. ISSN: 0021-972X
Karteris, E. and Randeva, HS. (2003) 'Orexin Receptors and G-Protein Coupling: Evidence for Another “Promiscuous” Seven Transmembrane Domain Receptor'. Journal of Pharmacological Sciences, 93 (1). pp. 126 - 128. ISSN: 1347-8613
Morrison, C., Vagnarelli, P., Sonoda, E., Takeda, S. and Earnshaw, WC. (2003) 'Sister chromatid cohesion and genome stability in vertebrate cells'. Biochemical Society Transactions, 31 (1). pp. 263 - 265. ISSN: 0300-5127
David, A., Peebles, D., Gregory, L., Themis, M., Cook, T., Knapton, H., et al. (2003) 'Towards fetal gene therapy for cystic fibrosis: ultrasound guided delivery of recombinant adenoviral vectors to the fetal sheep trachea results in efficient marker gene expression in the airway epithelia'. Journal of Obstetrics and Gynaecology, 23 (sup1). pp. S11 - S11. ISSN: 0144-3615
Makarov, EM., Makarova, OV., Urlaub, H., Gentzel, M., Will, CL., Wilm, M. and et al. (2002) 'Small nuclear ribonucleoprotein remodeling during catalytic activation of the spliceosome'. Science, 298 (5601). pp. 2205 - 2208. ISSN: 0036-8075
Bueno, D., Fernàndez-Rodríguez, J., Cardona, A., Hernàndez-Hernàndez, V. and Romero, R. (2002) 'A Novel Invertebrate Trophic Factor Related to Invertebrate Neurotrophins Is Involved in Planarian Body Regional Survival and Asexual Reproduction'. Developmental Biology, 252 (2). pp. 188 - 201. ISSN: 0012-1606
Eden, ER., Patel, DD., Sun, X-M., Burden, JJ., Themis, M., Edwards, M., et al. (2002) 'Restoration of LDL receptor function in cells from patients with autosomal recessive hypercholesterolemia by retroviral expression of ARH1'. Journal of Clinical Investigation, 110 (11). pp. 1695 - 1702. ISSN: 0021-9738
Ma, YL., Tolmachov, O., Themis, M., Poznansky, M., Coutelle, C. and Peters, NS. (2002) 'Enhanced gap-junctional coupling in connexin43 transduced skeletal myoblasts'.American-Heart-Association Abstracts From Scientific Sessions. CHICAGO, ILLINOIS. 17 - 20 November. LIPPINCOTT WILLIAMS & WILKINS. pp. 281 - 281. ISSN: 0009-7322
Morrison, C., Vagnarelli, P. and Earnshaw, WC. (2002) 'Chromosome biorientation and anaphase onset in cohesin-deficient cells following inhibition of topoisomerase II'.42nd Annual Meeting of the American-Society-for-Cell-Biology. SAN FRANCISCO, CALIFORNIA. 1 - 18 December. AMER SOC CELL BIOLOGY. pp. 310A - 311A. ISSN: 1059-1524
Wahab, NA., Weston, BS., Roberts, T. and Mason, RM. (2002) 'Connective Tissue Growth Factor and Regulation of the Mesangial Cell Cycle'. Journal of the American Society of Nephrology, 13 (10). pp. 2437 - 2445. ISSN: 1046-6673
Hillhouse, EW. and Karteris, E. (2002) 'Angiogenesis – the search for a molecular solution'. Trends in Endocrinology & Metabolism, 13 (8). pp. 323 - 323. ISSN: 1043-2760
Hofken, T. (2002) 'A role for cell polarity proteins in mitotic exit'. The EMBO Journal, 21 (18). pp. 4851 - 4862. ISSN: 0261-4189
Rajapakse, N., Silva, E. and Kortenkamp, A. (2002) 'Combining xenoestrogens at levels below individual no-observed-effect concentrations dramatically enhances steroid hormone action'. Environmental Health Perspectives, 110 (9). pp. 917 - 921. ISSN: 1552-9924 Open Access Link
Ma, Y., Tolmacho, O., Themis, M., Poznansky, M., Coutelle, C. and Peters, NS. (2002) 'Intercellular communication in connexin43 transfected skeletal myocytes'.Congress of the European-Society-of-Cardiology. BERLIN, GERMANY. 31 - 4 September. W B SAUNDERS CO LTD. pp. 42 - 42. ISSN: 0195-668X
Kortenkamp, A. (2002) 'Toxicology of mixtures'. TOXICOLOGY, 178 (1). pp. 34 - 35. ISSN: 0300-483X
Karteris, E. and Hillhouse, EW. (2002) 'Stress and the skin'. Trends in Endocrinology & Metabolism, 13 (6). pp. 232 - 232. ISSN: 1043-2760
Ma, DL., Tree, D., Yang, CH., Simon, M. and Axelrod, J. (2002) 'Feedback loops and gradients determine cortical domains during planar cell polarity signaling.'. DEVELOPMENTAL BIOLOGY, 247 (2). pp. 485 - 485. ISSN: 0012-1606
Dellaire, G., Makarov, EM., Cowger, JJ., Longman, D., Sutherland, HG., Lührmann, R., et al. (2002) 'Mammalian PRP4 kinase copurifies and interacts with components of both the U5 snRNP and the N-CoR deacetylase complexes'. Mol Cell Biol, 22 (14). pp. 5141 - 5156. ISSN: 0270-7306
Zervou, S. (2002) 'Steroids mediate the expression of cytoplasmic and membrane-linked components in human myometrial cells'. Molecular Human Reproduction, 8 (7). pp. 597 - 605. ISSN: 1360-9947
Hillhouse, EW. and Karteris, E. (2002) 'Expression of multiple corticotropin-releasing hormone receptors in the human heart [1] (multiple letter)'. Journal of Clinical Endocrinology and Metabolism, 87 (6). pp. 2992 - 2993. ISSN: 0021-972X