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Tzelepis, K., De Braekeleer, E., Aspris, D., Barbieri, I., Vijayabaskar, MS., Liu, WH., et al. (2018) 'SRPK1 maintains acute myeloid leukemia through effects on isoform usage of epigenetic regulators including BRD4'. Nature Communications, 9 (1). pp. 5378. ISSN: 2041-1723 Open Access Link

Journal article

Gil, RS., Amin, H., Vinciotti, V. and Vagnarelli, P. (2018) 'Regulation of HP1 alpha binding in human cells.'. AMER SOC CELL BIOLOGY. ISSN: 1059-1524

Conference paper

Gokhan, E. and Vagnarelli, P. (2018) 'Repo-Man/PP1 regulates lamin A S22 phosphorylation.'. AMER SOC CELL BIOLOGY. ISSN: 1059-1524

Conference paper

Midgley-Smith, S., Dimude, J. and Rudolph, C. (2018) 'A role for 3’ exonucleases at the final stages of chromosome duplication in Escherichia coli'. Nucleic Acids Research, 47 (4). pp. 1847 - 1860. ISSN: 0305-1048 Open Access Link

Journal article

Karteris, E., Patel, VH., Chen, J., Kyrou, I., Mattu, H., Dimitriadis, G., et al. (2018) 'Functional Cardiac Orexin Receptors: Role of Orexin-B/Orexin 2 Receptor in Myocardial Protection.'. Clinical Science, 132 (24). pp. 2547 - 2564. ISSN: 0143-5221 Open Access Link

Journal article

Papa, S., Choy, PM. and Bubici, C. (2018) 'The ERK and JNK pathways in the regulation of metabolic reprogramming.'. Oncogene, 38 (13). pp. 2223 - 2240. ISSN: 0950-9232 Open Access Link

Journal article

Mehmet, B., Faragher, R., Worthington, G., Meinke, P., Kerr, A., Sammy, A., et al. (2018) 'Telomere elongation through hTERT immortalization leads to chromosome repositioning in control cells and genomic instability in Hutchinson-Gilford progeria syndrome fibroblasts, expressing a novel SUN1 isoform'. Genes, Chromosomes and Cancer, 58 (6). pp. 341 - 356. ISSN: 1045-2257 Open Access Link

Journal article

Al-Allaf, FA., Abduljaleel, Z., Athar, M., Taher, MM., Khan, W., Mehmet, H., et al. (2018) 'Modifying inter-cistronic sequence significantly enhances IRES dependent second gene expression in bicistronic vector: Construction of optimised cassette for gene therapy of familial hypercholesterolemia'. Non-coding RNA Research, 4 (1). pp. 1 - 14. ISSN: 2468-0540 Open Access Link

Journal article

Tomita, K. and Collopy, LC. (2018) 'Telomeres, Telomerase, and Cancer', in Boffetta, P. and Hainaut, P. (eds.) Encyclopedia of Cancer, 3rd edition. Academic Press. , 3. pp. 437 - 454. ISBN 10: 0128124849. ISBN 13: 9780128012383.

Book chapter

Lee, NCW., Carella, MA., Papa, S. and Bubici, C. (2018) 'High expression of glycolytic genes in Cirrhosis correlates with the risk of developing liver cancer'. Frontiers in Cell and Developmental Biology, 6 (OCT). pp. 138. ISSN: 2296-634X Open Access Link

Journal article

Rogers‑Broadway, K-R., Kumar, J., Sisu, C., Wander, G., Mazey, E., Jeyaneethi, J., et al. (2018) 'Differential expression of mTOR components in endometriosis and ovarian cancer: Effects of rapalogues and dual kinase inhibitors on mTORC1 and mTORC2 stoichiometry'. International Journal of Molecular Medicine, 43 (1). pp. 47 - 56. ISSN: 1107-3756 Open Access Link

Journal article

Frankish, A., Diekhans, M., Ferreira, AM., Johnson, R., Jungreis, I., Loveland, J., et al. (2018) 'GENCODE reference annotation for the human and mouse genomes'. Nucleic Acids Research, 47 (D1). pp. D766 - D773. ISSN: 0305-1048 Open Access Link

Journal article

Lilue, J., Doran, AG., Fiddes, IT., Abrudan, M., Armstrong, J., Bennett, R., et al. (2018) 'Sixteen diverse laboratory mouse reference genomes define strain specific haplotypes and novel functional loci'. Nature Genetics, 50 (11). pp. 1574 - 1583. ISSN: 1061-4036 Open Access Link

Journal article

Taxvig, C., Scholze, M., Kortenkamp, A., Boberg, J., Svingen, T., Ermler, S., et al. (2018) 'Prediction of adverse male reproductive health effects by integrating in vitro data and physiologically-based kinetic modelling'.54th Congress of the European-Societies-of-Toxicology (EUROTOX) - Toxicology Out of the Box. Brussels, BELGIUM. Elsevier BV. pp. S61 - S61. ISSN: 0378-4274

Conference paper

Dorne, J-LCM., Benford, D., Ragas, A., Posthuma, L., Kass, GE., Manini, P., et al. (2018) 'Harmonised risk assessment for human health, animal health and ecological risk assessment of combined exposure to multiple chemicals: a food and feed safety perspective'.54th Congress of the European-Societies-of-Toxicology (EUROTOX) - Toxicology Out of the Box. Brussels, BELGIUM. Elsevier BV. pp. S37 - S38. ISSN: 0378-4274

Conference paper

Moris, N., Edri, S., Seyres, D., Kulkarni, R., Domingues, AF., Balayo, T., et al. (2018) 'Histone Acetyltransferase KAT2A Stabilizes Pluripotency with Control of Transcriptional Heterogeneity'. Stem Cells, 36 (12). pp. 1828 - 1838. ISSN: 1066-5099 Open Access Link

Journal article

Harvey, AJ. (2018) 'Overview of Cell Signaling Pathways in Cancer', in Badve, S. and Kumar, G. (eds.) Predictive Biomarkers in Oncology Applications in Precision Medicine. Cham, Switzerland : Springer. pp. 167 - 182. ISBN 10: 3319952277. ISBN 13: 978-3-319-95227-7. Open Access Link

Book chapter

Tummala, H., Collopy, LC., Walne, AJ., Ellison, A., Cardoso, S., Aksu, T., et al. (2018) 'Homozygous OB-fold variants in telomere protein TPP1 are associated with dyskeratosis congenita–like phenotypes'. Blood, 132 (12). pp. 1349 - 1353. ISSN: 0006-4971 Open Access Link

Journal article

Bopp, SK., Barouki, R., Brack, W., Dalla Costa, S., Dorne, JLCM., Drakvik, PE., et al. (2018) 'Current EU research activities on combined exposure to multiple chemicals'. Environment International, 120. pp. 544 - 562. ISSN: 0160-4120 Open Access Link

Journal article

Vagnarelli, P. and Alessi, D. (2018) 'PP1 Phosphatase Complexes: Undruggable No Longer'. Cell, 174 (5). pp. 1049 - 1051. ISSN: 1097-4172 Open Access Link

Journal article

Dimude, JU., Midgley-Smith, SL. and Rudolph, CJ. (2018) 'Replication-transcription conflicts trigger extensive DNA degradation in Escherichia coli cells lacking RecBCD'. Mutation Research/DNA Repair, 70. pp. 37 - 48. ISSN: 0921-8777 Open Access Link

Journal article

Sales Gil, R. and Vagnarelli, P. (2018) 'Ki-67: More Hidden behind a ‘Classic Proliferation Marker'. Trends in Biochemical Sciences, 43 (10). pp. 747 - 748. ISSN: 0968-0004 Open Access Link

Journal article

Bridger, JM., Brindley, PJ. and Knight, M. (2018) 'The snail Biomphalaria glabrata as a model to interrogate the molecular basis of complex human diseases'. PLoS Neglected Tropical Diseases, 12 (8). pp. e0006552 - e0006552. ISSN: 1935-2727 Open Access Link

Journal article

Tijani, M., Munis, AM., Perry, C., Sanber, K., Ferraresso, M., Mukhopadhyay, T., et al. (2018) 'Lentivector Producer Cell Lines with Stably Expressed Vesiculovirus Envelopes'. Molecular Therapy - Methods and Clinical Development, 10. pp. 303 - 312. ISSN: 2329-0501 Open Access Link

Journal article

Dimude, JU., Stein, M., Andrzejewska, EE., Khalifa, MS., Gajdosova, A., Retkute, R., et al. (2018) 'Origins Left, Right, and Centre: Increasing the Number of Initiation Sites in the Escherichia coli Chromosome'. Genes, 9 (8). pp. 1 - 21. ISSN: 2073-4425 Open Access Link

Journal article

Seda, M., Geerlings, M., Lim, P., Jeyabalan-Srikaran, J., Cichon, A-C., Scambler, PJ., et al. (2018) 'An FDA-Approved Drug Screen for Compounds Influencing Craniofacial Skeletal Development and Craniosynostosis'. Molecular Syndromology, 10 (1-2). pp. 98 - 114. ISSN: 1661-8769 Open Access Link

Journal article

Sales Gil, R. and Vagnarelli, P. (2018) 'Protein Phosphatases in chromatin structure and function'. BBA Molecular Cell Research, 1886 (1). pp. 90 - 101. ISSN: 0167-4889 Open Access Link

Journal article

Kortenkamp, A. and Faust, M. (2018) 'Regulate to reduce chemical mixture risk'. Science, 361 (6399). pp. 224 - 226. ISSN: 0036-8075

Journal article

Mansfield, L., Kay, T., Meads, C., Grigsby Duffy, L., Lane, J., John, A., et al. (2018) 'Sport and dance interventions for healthy young people (15-24 years) to promote subjective wellbeing: A systematic review'. British Medical Journal Open, 8 (7). pp. 1 - 16. ISSN: 2044-6055 Open Access Link

Journal article

Themis, M., Takeuchi, Y., Henkaerts, E., Wang, W., Weiss, F., Al Haque, S., et al. (2018) 'A unique cost effective humanised genotoxicity model bringing safety assessment to gene therapy'. HUMAN GENE THERAPY. pp. A5 - A5. ISSN: 1043-0342

Conference paper

Midgley-Smith, SL., Dimude, JU., Taylor, T., Forrester, NM., Upton, AL., Lloyd, RG. and et al. (2018) 'Chromosomal over-replication in Escherichia coli recG cells is triggered by replication fork fusion and amplified if replichore symmetry is disturbed'. Nucleic Acids Research, 46 (15). pp. 7701 - 7715. ISSN: 0305-1048 Open Access Link

Journal article

Bikkul, M., Clements, C., Godwin, L., Goldberg, M., Kill, I. and Bridger, JM. (2018) 'Farnesyltransferase inhibitor and rapamycin correct aberrant genome organisation and decrease DNA damage respectively, in Hutchinson–Gilford progeria syndrome fibroblasts'. Biogerontology, 19 (6). pp. 579 - 602. ISSN: 1389-5729 Open Access Link

Journal article

Papa, S. and Bubici, C. (2018) 'Feeding the Hedgehog: A new meaning for JNK signalling in liver regeneration'. Journal of Hepatology, 69 (3). pp. 572 - 574. ISSN: 0168-8278 Open Access Link

Journal article

Themis, M. (2018) 'Three-dimensional cell culture: From evolution to revolution'. Philos Trans R Soc Lond B Biol Sci, 373 (1750). pp. 20170216 - 20170216. ISSN: 0962-8436 Open Access Link

Journal article

Hall, M., Chudasama, D., Roberts, C., Stone, N., Vardaki, M., Urnowitz, H., et al. (2018) 'Applications of liquid biopsies as prognostic markers in patients (pts) with advanced ovarian cancer (AOC) on metronomic cyclophosphamide (MCy) with or without nintedanib (N) (Trans METRO-BIBF).'. American Society of Clinical Oncology (ASCO). pp. e24065 - e24065. ISSN: 0732-183X

Conference paper

Yue, W., Wang, Z., Chen, H., Payne, A. and Liu, X. (2018) 'Machine Learning with Applications in Breast Cancer Diagnosis and Prognosis'. Designs, 2 (2). pp. 13 - 13. ISSN: 2411-9660 Open Access Link

Journal article

Al-Mozaini, M., Tsolaki, AG., Abdul-Aziz, M., Abozaid, SM., Al-Ahdal, MN., Pathan, AA., et al. (2018) 'Human properdin modulates macrophage: Mycobacterium bovis BCG interaction via thrombospondin repeats (TSR) 4 and 5'. Frontiers in Immunology, 9 (MAY). pp. 533. ISSN: 1664-3224 Open Access Link

Journal article

Slijepcevic, P. (2018) 'Genome dynamics over evolutionary time: “C-value enigma” in light of chromosome structure'. Mutation Research - Genetic Toxicology and Environmental Mutagenesis, 836 (Pt A). pp. 22 - 27. ISSN: 1383-5718 Open Access Link

Journal article

Bains, SK., Chapman, K., Bright, S., Senan, A., Kadhim, M. and Slijepcevic, P. (2018) 'Effects of ionizing radiation on telomere length and telomerase activity in cultured human lens epithelium cells'. International Journal of Radiation Biology, 95 (1). pp. 1 - 10. ISSN: 0955-3002

Journal article

Karteris, E. (2018) 'Prognostic value of the DNA Integrity Index in patients with malignant lung tumours'. Oncotarget, 9 (30). pp. 21281 - 21288. ISSN: 1949-2553 Open Access Link

Journal article

Chudasama, DY., Aladag, Z., Felicien, MI., Hall, M., Beeson, J., Asadi, N., et al. (2018) 'Prognostic value of the DNA integrity index in patients with malignant lung tumors'. Oncotarget, 9 (30). pp. 21281 - 21288. ISSN: 1949-2553 Open Access Link

Journal article

Tomita, K. (2018) 'How long does telomerase extend telomeres? Regulation of telomerase release and telomere length homeostasis'. Current Genetics, 64 (6). pp. 1177 - 1181. ISSN: 0172-8083 Open Access Link

Journal article

Thybert, D., Roller, M., Navarro, FCP., Fiddes, I., Streeter, I., Feig, C., et al. (2018) 'Repeat associated mechanisms of genome evolution and function revealed by the Mus caroli and Mus pahari genomes'. Genome Research, 28 (4). pp. 448 - 459. ISSN: 1088-9051 Open Access Link

Journal article

Altenburger, R., Scholze, M., Busch, W., Escher, BI., Jakobs, G., Krauss, M., et al. (2018) 'Mixture effects in samples of multiple contaminants – An inter-laboratory study with manifold bioassays'. Environment International, 114. pp. 95 - 106. ISSN: 0160-4120 Open Access Link

Journal article

Burdakov, VS., Kovalev, RA., Pantina, RA., Varfolomeeva, EY., Makarov, EM. and Filatov, MV. (2018) 'Exosomes Transfer p53 between Cells and Can Suppress Growth and Proliferation of p53-Negative Cells'. Cell and Tissue Biology, 12 (1). pp. 20 - 26. ISSN: 1990-519X Open Access Link

Journal article

Ereku, LT., Mackay, RE., Craw, P., Naveenathayalan, A., Stead, T., Branavan, M. and et al. (2018) 'RPA using a multiplexed cartridge for low cost point of care diagnostics in the field'. Analytical Biochemistry, 547. pp. 84 - 88. ISSN: 0003-2697 Open Access Link

Journal article

Collopy, LC., Ware, TL., Goncalves, T., Í Kongsstovu, S., Yang, Q., Amelina, H., et al. (2018) 'LARP7 family proteins have conserved function in telomerase assembly'. Nature Communications, 9 (1). pp. 1 - 8. ISSN: 2041-1723 Open Access Link

Journal article

Sales Gil, R., de Castro, IJ., Berihun, J. and Vagnarelli, P. (2018) 'Protein Phosphatases at the Nuclear Envelope'. Biochemical Society Transactions, 46 (1). pp. 173 - 182. ISSN: 0300-5127 Open Access Link

Journal article

Chehade, HEH., Harvey, A., Wazir, U., Jiang, WG. and Mokbel, K. (2018) 'mRNA expression of PTK6V1 and PTKV2 in human breast cancer'. CANCER RESEARCH. ISSN: 0008-5472

Conference paper

Harvey, A., Foster, H., Thorpe, M. and Karteris, E. (2018) 'Breast tumour kinase and its role in mTOR signalling'. CANCER RESEARCH. ISSN: 0008-5472

Conference paper

Cantarella, CD., Ragusa, D. and Tosi, S. (2018) 'Insights into maternal diet for the prevention of childhood leukaemia'. Hematology and Leukemia, 6 (1). pp. 1 - 1. ISSN: 2052-434X Open Access Link

Journal article