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Dr Ines Castro
Lecturer in Genomics

Summary

Ines is a Lecturer in Genomics since 2023. She is passionate about the genome and how genes switch ON/OFF in a timely and spatially regulated manner. She left Portugal in 2007 to study gene expression regulation in yeast (UMC Utrecht, the Netherlands) and flies (Netherlands Cancer Institute, the Netherlands). She did her PhD at Imperial College London investigating the spatial location of chromosomes in Huntington’s Disease (London, UK). During her two postdocs she looked at chromatin regulation during cell cycle (Brunel University London, UK) and HIV-1 infection (Heidelberg University/EMBL Germany). She is particularly interested at the nuclear periphery and how the genome is organised underneath the Nuclear Pore Complex, the gate of HIV-1 into the nuclei.

Qualifications

PhD, Imperial College London 

Fellow, Higher Education Academy

Responsibility

Lecturer/Content Expert, Introduction to Medical Sciences 1, Brunel Medical School

House tutor, Brunel Medical School

Newest selected publications

de Castro, IJ., Lucic, B. and Lusic, M. (2021) 'Viruses in the Nucleus'. Cold Spring Harbor Perspectives in Biology, 13 (8). pp. 1 - 19. ISSN: 1943-0264 Open Access Link

Journal article

de Castro, IJ., Toner, B., Xie, SQ., Swingland, J., Hodges, A., Tabrizi, SJ., et al. (2021) 'Altered nuclear architecture in blood cells from Huntington’s disease patients'. Neurological Sciences, 43 (1). pp. 379 - 385. ISSN: 1590-1874

Journal article

de Castro, IJ. and Lusic, M. (2019) 'Navigating through the nucleus with a virus'. Current Opinion in Genetics and Development, 55. pp. 100 - 105. ISSN: 0959-437X

Journal article

Sales Gil, R., de Castro, IJ., Berihun, J. and Vagnarelli, P. (2018) 'Protein Phosphatases at the Nuclear Envelope'. Biochemical Society Transactions, 46 (1). pp. 173 - 182. ISSN: 0300-5127 Open Access Link

Journal article

de Castro, IJ., Sales Gil, R., Ligammari, L., Di Giacinto, ML. and Vagnarelli, P. (2017) 'CDK1 and PLK1 co-ordinate the disassembly and re-assembly of the Nuclear Envelope in vertebrate mitosis'. Oncotarget, 9 (8). pp. 7763 - 7773. ISSN: 1949-2553 Open Access Link

Journal article
More publications(8)