Dr Keith Redpath
Lecturer in Biosciences (Vascular Biology)
Summary
Dr Keith Allen-Redpath graduated with a BSc (Hons) in Biomedical Sciences (Physiology) from the University of Aberdeen, Scotland, in 2009. He then undertook a PhD in the laboratory of Professor Graeme Nixon at Aberdeen, investigating how zinc deficiency affects vascular smooth muscle cell signalling within the aorta and carotid arteries. This PhD was part-funded by the National Research Foundation of Korea (NRF), and he was awarded his doctorate in 2013. Following his PhD, Keith moved to Cardiff, Wales, to take up a five-year British Heart Foundation (BHF) Research Associate position in the laboratory of Professor Valerie O'Donnell, focusing on how oxidized phospholipids contribute to the development of abdominal aortic aneurysms (AAA). In 2018, he joined the University of Reading, England, as a Senior Research Fellow in the laboratory of Professor Parveen Yaqoob, where he developed a strong interest in extracellular vesicles and their roles in vascular diseases, including ischaemic heart disease (IHD) and AAA. In January 2023, Keith was appointed Lecturer in Vascular Biology at Brunel University London, where his research continues to focus on the role of extracellular vesicles in vascular pathology, with the aim of identifying novel therapeutic targets in cardiovascular disease.
Qualifications
- BSc (Hons) Biomedical Sciences, Physiology (University of Aberdeen)
- PhD Biomedical Sciences, Physiology (University of Aberdeen)
- Fellow of the Institute of Biomedical Sciences (FIBMS)
- Fellow of the Higher Education Academy (FHEA, Brunel University of London)
Newest selected publications
Protty, MB., Tyrrell, VJ., Allen-Redpath, K., Soyama, S., Hajeyah, AA., Costa, D., et al. (2024) 'Thrombin Generation Is Associated With Extracellular Vesicle and Leukocyte Lipid Membranes in Atherosclerotic Cardiovascular Disease'. Arteriosclerosis Thrombosis and Vascular Biology, 44 (9). pp. 2038 - 2052. ISSN: 1079-5642 Open Access Link
Bozbas, E., Zhou, R., Soyama, S., Allen-Redpath, K., Mitchell, JL., Fisk, HL., et al. (2024) 'Dietary n-3 polyunsaturated fatty acids alter the number, fatty acid profile and coagulatory activity of circulating and platelet-derived extracellular vesicles: a randomized, controlled crossover trial'. American Journal of Clinical Nutrition, 119 (5). pp. 1175 - 1186. ISSN: 0002-9165 Open Access Link
Hajeyah, AA., Protty, MB., Paul, D., Costa, D., Omidvar, N., Morgan, B., et al. (2024) 'Phosphatidylthreonine is a procoagulant lipid detected in human blood and elevated in coronary artery disease'. Journal of Lipid Research, 65 (1). pp. 1 - 15. ISSN: 0022-2275 Open Access Link
Zhou, R., Bozbas, E., Allen-Redpath, K. and Yaqoob, P. (2022) 'Circulating Extracellular Vesicles Are Strongly Associated With Cardiovascular Risk Markers'. Frontiers in Cardiovascular Medicine, 9. pp. 1 - 14. ISSN: 2297-055X Open Access Link
Allen-Redpath, K., Aldrovandi, M., Lauder, SN., Gketsopoulou, A., Tyrrell, VJ., Slatter, DA., et al. (2019) 'Phospholipid membranes drive abdominal aortic aneurysm development through stimulating coagulation factor activity'. Proceedings of the National Academy of Sciences of the United States of America, 116 (16). pp. 8038 - 8047. ISSN: 0027-8424 Open Access Link