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Dr Svetlana Ignatova

Dr Svetlana Ignatova
Reader - Advanced Bioprocessing

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Sutherland, IA., Peng, A., Hewitson, P., Chen, L. and Ignatova, S. (2018) 'The effect of increasing centrifugal acceleration/force and flow rate for varying column aspect ratios on separation efficiency in Counter-Current Chromatography'. Journal of Chromatography A, 1581-1582. pp. 80 - 90. ISSN: 0021-9673 Open Access Link

Journal article

Peng, A., Hewitson, P., Sutherland, I., Chen, L. and Ignatova, S. (2018) 'How changes in column geometry and packing ratio can increase sample load and throughput by a factor of fifty in Counter-Current Chromatography'. Journal of Chromatography A, 1580. pp. 120 - 125. ISSN: 0021-9673 Open Access Link

Journal article

DeAmicis, C., Yang, Q., Bright, C., Edwards, NA., Harris, GH., Kaur, S., et al. (2017) 'Development of a Scalable and Sustainable High Performance CounterCurrent Chromatography (HPCCC) Purification for Spinosyn A and Spinosyn D from Spinosad'. Organic Process Research and Development, 21 (10). pp. 1638 - 1643. ISSN: 1083-6160 Open Access Link

Journal article

das Neves Costa, F., Hubert, J., Borie, N., Kotland, A., Hewitson, P., Ignatova, S. and et al. (2017) 'Schinus terebinthifolius countercurrent chromatography (Part III): Method transfer from small CCC column to preparative CPC ones as a part of method development'. Journal of Chromatography A, 1487. pp. 77 - 82. ISSN: 0021-9673 Open Access Link

Journal article

de Souza Figueiredo, F., Celano, R., de Sousa Silva, D., das Neves Costa, F., Hewitson, P., Ignatova, S., et al. (2016) 'Countercurrent chromatography separation of saponins by skeleton type from Ampelozizyphus amazonicus for off-line ultra-high-performance liquid chromatography/high resolution accurate mass spectrometry analysis and characterisation.'. Journal of chromatography. A, 1481. pp. 92 - 100. ISSN: 0021-9673 Open Access Link

Journal article

Peng, A., Hewitson, P., Ye, H., Zu, L., Garrard, I., Sutherland, I., et al. (2016) 'Sample injection strategy to increase throughput in counter-current chromatography: Case study of Honokiol purification'. Journal of Chromatography A, 1476. pp. 19 - 24. ISSN: 0021-9673 Open Access Link

Journal article

Costa, FD., Vieira, MN., Garrard, I., Hewitson, P., Jerz, G., Leitão, GG. and et al. (2016) 'Schinus terebinthifolius countercurrent chromatography (Part II): Intra-apparatus scale-up and inter-apparatus method transfer.'. Journal of chromatography A, 1466. pp. 76 - 83. ISSN: 0021-9673 Open Access Link

Journal article

Ward, DP., Cárdenas-Fernández, M., Hewitson, P., Ignatova, S. and Lye, GJ. (2015) 'Centrifugal partition chromatography in a biorefinery context: Separation of monosaccharides from hydrolysed sugar beet pulp'. Journal of Chromatography A, 1411. pp. 84 - 91. ISSN: 0021-9673 Open Access Link

Journal article

Marsden-Jones, S., Colclough, N., Garrard, I., Sumner, N. and Ignatova, S. (2015) 'Using quantitative structure activity relationship models to predict an appropriate solvent system from a common solvent system family for countercurrent chromatography separation'. Journal of Chromatography A, 1398. pp. 66 - 72. ISSN: 0021-9673

Journal article

Zhang, M., Ignatova, S., Hu, P., Liang, Q., Wang, Y., Sutherland, IA., et al. (2012) 'Cost-efficient and process-efficient separation of geniposide from Gardenia jasminoides Ellis by high-performance counter-current chromatography'. Separation and Purification Technology, 89. pp. 193 - 198. ISSN: 1383-5866

Journal article

Garrard, I., Sutherland, I., Fisher, D., Ignatova, SN., van den Heuvel, R. and Grudzien, L. (2011) 'Liquid-liquid chromatography: why a liquid stationary phase is so exciting'.Separation Science Europe: New Horizons in Separation and Detection Techniques. The Royal Institution, London, UK. 10 - 11 October. [unpublished]

Conference paper

Sutherland, I., Ignatova, S., Hewitson, P., Janaway, L., Wood, P., Edwards, N., et al. (2011) 'Scalable technology for the extraction of pharmaceutics (STEP): The transition from academic knowhow to industrial reality'. Journal of Chromatography A, 1218 (36). pp. 6114 - 6121. ISSN: 1873-3778

Journal article

Ignatova, S., Hewitson, P., Mathews, B. and Sutherland, I. (2011) 'Evaluation of dual flow counter-current chromatography and intermittent counter-current extraction'. Journal of Chromatography A, 1218 (36). pp. 6102 - 6106. ISSN: 0021-9673

Journal article

Ignatova, S., Sumner, N., Colclough, N. and Sutherland, I. (2011) 'Gradient elution in counter-current chromatography: A new layout for an old path'. Journal of Chromatography A, 1218 (36). pp. 6053 - 6060. ISSN: 1873-3778

Journal article

Ignatova, SN. (2011) 'Role of countercurrent chromatography in modernisation of Chinese herbal medicines'.World Congress of Chinese Medicine (WCCM2011). London, UK. 2 - 3 September. [unpublished]

Conference paper

Sutherland, IA., Ignatova, SN., Simmonds, M. and Sendker, J. (2011) 'Good practice in TCMs (GPTCM): preliminary results on the quality of botanical origin, processing and extraction information contained in papers on Cornus Officinalis in the last three years'.The 10th Meeting of Consortium for Globilisation of Chinese Medicine (CGCM2011). Shanghai, China. 26 - 28 August. [unpublished]

Conference paper

Ignatova, SN., Douillet, N., Hewitson, P., Thickitt, C., Viliminot, E., Johns, D., et al. (2011) 'API recovery from pharmaceutical waste streams by high performance counter-current chromatography (HPCCC) and intermittent counter-current extraction (ICcE)'.International Symposium, Exhibit and Workshops on Preparative and Process Chromatography (PREP 2011). Boston, USA. 10 - 13 July. AMER CHEMICAL SOC. pp. 236 - 237. ISSN: 0065-7727

Conference paper

DeAmicis, C., Edwards, NA., Giles, MB., Harris, GH., Hewitson, P., Janaway, L. and et al. (2011) 'Comparison of preparative reversed phase liquid chromatography and countercurrent chromatography for the kilogram scale purification of crude spinetoram insecticide'. Journal of Chromatography A, 1218 (36). pp. 6122 - 6127. ISSN: 0021-9673

Journal article

Hewitson, P., Ignatova, S. and Sutherland, I. (2011) 'Intermittent counter-current extraction-effect of the key operating parameters on selectivity and throughput'. Journal of Chromatography A, 1218 (36). pp. 6072 - 6078. ISSN: 0021-9673

Journal article

Zhang, M., Ignatova, S., Hu, P., Liang, Q., Wang, Y., Sutherland, IA., et al. (2011) 'Development of a strategy and process parameters for a green process in counter-current chromatography: Purification of tanshinone IIA and cryptotanshinone from Salvia miltiorrhiza Bunge as a case study'. Journal of Chromatography A, 1218 (36). pp. 6031 - 6037. ISSN: 1873-3778

Journal article

Ignatova, SN., Hewitson, P. and Sutherland, IA. (2010) 'New ways to solve old problems: purification of waste streams'.13th Symposium on Preparative and Industrial Chromatography and Allied Techniques (SPICA2010). Stockholm, Sweden. 12 - 15 September. [unpublished]

Conference paper

Hewitson, P., Ignatova, SN. and Sutherland, IA. (2010) 'Effect of the key operating parameters on the efficiency of intermittent counter-current extraction'.6th International Symposium on Countercurrent Chromatography (CCC2010). Lyon, France. 28 - 30 July. [unpublished]

Conference paper

Ignatova, SN., Sumner, N., Colclough, N. and Sutherland, IA. (2010) 'Gradient elution in counter-current chromatography: a new layout for an old path'.6th International Symposium on Countercurrent Chromatography (CCC2010). Lyon, France. 28 - 30 July. [unpublished]

Conference paper

Ignatova, SN., Hewitson, P. and Sutherland, IA. (2010) 'χEvaluation of dual flow counter-current chromatography and intermittent counter-current extraction'.6th International Symposium on Countercurrent Chromatography (CCC2010). Lyon France. 28 - 30 July. [unpublished]

Conference paper

Sutherland, IA., Ignatova, SN., Hewitson, P., Janaway, L., Wood, P., Edwards, N., et al. (2010) 'Scalable technology for the extraction of pharmaceutics (STEP): the transition from academic knowhow to industrial reality'.6th International Symposium on Countercurrent Chromatography (CCC2010). Lyon, France. 28 - 30 July. [unpublished]

Conference paper

Zhang, M., Ignatova, SN., Hu, P., Liang, Q., Wang, Y., Luo, G., et al. (2010) 'Exploiting counter-current chromatography as a green process: purification of tanshinone IIA and cryptotanshinone from Salvia miltiorrhiza Bunge as a case study'.6th International Symposium on Countercurrent Chromatography (CCC2010). Lyon, France. 28 - 30 July. [unpublished]

Conference paper

Ignatova, S., Hawes, D., van den Heuvel, R., Hewitson, P. and Sutherland, IA. (2010) 'A new non-synchronous preparative counter-current centrifuge – the next generation of dynamic extraction/chromatography devices with independent mixing and settling control, which offer a step change in efficiency'. Journal of Chromatography A, 1217 (1). pp. 34 - 39. ISSN: 0021-9673

Journal article

Garrard, I., Sutherland, I., Fisher, D., Ignatova, SN. and van den Heuvel, R. (2009) 'Scale up in countercurrent chromatography'.CCC Workshop. Federal University of Rio de Janiero, Brazil. 14 - 18 December. [unpublished]

Conference paper

Garrard, I., Sutherland, I., Fisher, D., Ignatova, SN. and van den Heuvel, R. (2009) 'CCC solvent systems for natural products separations'.CCC Workshop. Federal University of Rio de Janiero, Brazil. 14 - 18 December. [unpublished]

Conference paper

Sutherland, IA., Hewitson, P. and Ignatova, S. (2009) 'Scale-up of counter-current chromatography: Demonstration of predictable isocratic and quasi-continuous operating modes from the test tube to pilot/process scale'. Journal of Chromatography A, 1216 (50). pp. 8787 - 8792. ISSN: 0021-9673

Journal article

Garrard, I., Sutherland, I., Fisher, D., Ignatova, SN. and van den Heuvel, R. (2009) 'High capacity CCC for fast isolation of natural products'.Royal Society of Chemistry Conference "Functional Molecules from Natural Sources". Oxford, UK. 6 - 8 July. [unpublished]

Conference paper

Ye, H., Ignatova, S., Peng, A., Chen, L. and Sutherland, IA. (2009) 'Optimising resolution for a preparative separation of Chinese herbal medicine using a surrogate model sample system'. Journal of Chromatography A, 1216 (26). pp. 5101 - 5105. ISSN: 0021-9673

Journal article

Hawes, D., Ignatova, SN., van den Heuvel, R. and Sutherland, IA. (2009) 'Non-synchronous preparative CCC – the next generation counter-current centrifuge where phase separation and mixing can be independently controlled'.15th International Conference on Biopartitioning and Purification (BPP2009). Brunel University, Uxbridge, UK. 14 - 19 June. [unpublished]

Conference paper

Rubio, N., Ignatova, SN., Sutherland, IA. and Minguillon, C. (2009) 'Multiple dual-mode counter-current chromatography applied to chiral separations'.15th International Conference on Biopartitioning and Purification (BPP2009). Brunel University, Uxbridge, UK. 14 - 19 June. [unpublished]

Conference paper

Garrard, I., Sutherland, I., Fisher, D., Ignatova, SN. and van den Heuvel, R. (2009) 'The role of counter-current chromatography in the fractionation and identification of plant based extracts'.International Exhibition-Congress on Chemical Engineering, Environmental Protection and Biotechnology (ACEMA2009). Frankfurt am Main, Germany. 11 - 15 May. [unpublished]

Conference paper

Sutherland, IA., Hewitson, P. and Ignatova, S. (2009) 'New 18-l process-scale counter-current chromatography centrifuge'. Journal of Chromatography A, 1216 (19). pp. 4201 - 4205. ISSN: 0021-9673

Journal article

Hewitson, P., Ignatova, S., Ye, H., Chen, L. and Sutherland, I. (2009) 'Intermittent counter-current extraction as an alternative approach to purification of Chinese herbal medicine'. Journal of Chromatography A, 1216 (19). pp. 4187 - 4192. ISSN: 0021-9673

Journal article

Zhang, M., Ignatova, S., Liang, Q., Wu Jun, F., Sutherland, I., Wang, Y. and et al. (2009) 'Rapid and high-throughput purification of salvianolic acid B from Salvia miltiorrhiza Bunge by high-performance counter-current chromatography'. Journal of Chromatography A, 1216 (18). pp. 3869 - 3873. ISSN: 0021-9673

Journal article

Garrard, I., Sutherland, I., Fisher, D., Ignatova, SN. and van den Heuvel, R. (2009) 'Developing a large scale purification protocol'.4th International Conference on Bioprospecting (BIOPROSP2009). Radisson SAS Hotel, Tromso, Norway. 24 - 25 February. [unpublished]

Conference paper

Garrard, I., Sutherland, I., Fisher, D., Ignatova, SN. and van den Heuvel, R. (2009) 'Large scale purification of biomolecules: advantages of a liquid stationary phase'.4th International Conference on Bioprospecting (BIOPROSP2009). Radisson SAS Hotel, Tromso, Norway. 24 - 25 February. [unpublished]

Conference paper

Rubio, N., Ignatova, S., Minguillón, C. and Sutherland, IA. (2009) 'Multiple dual mode countercurrent chromatography applied to chiral separations using a (S)-naproxen derivative as chiral selector'. Journal of Chromatography A, 1216 (48). pp. 8505 - 8511. ISSN: 0021-9673

Journal article

Berthod, A., Ignatova, S. and Sutherland, IA. (2009) 'Advantages of a small-volume counter-current chromatography column'. Journal of Chromatography A, 1216 (19). pp. 4169 - 4175. ISSN: 0021-9673

Journal article

Ye, H., Ignatova, S., Luo, H., Li, Y., Peng, A., Chen, L. and et al. (2008) 'Preparative separation of a terpenoid and alkaloids from Tripterygium wilfordii Hook. f. using high-performance counter-current chromatography: comparison of various elution and operating strategies'. Journal of Chromatography A, 1213 (2). pp. 145 - 153. ISSN: 0021-9673

Journal article

Garrard, I., Sutherland, I., Fisher, D., Ignatova, SN. and van den Heuvel, R. (2008) 'Dynamic extraction: an innovative, scaleable processing technology'.Scientific Update Conference, The Scale Up of Chemical Processes. Sheraton Hotel, Rome, Italy. 15 - 17 September. [unpublished]

Conference paper

Hewitson, P., Ignatova, SN., Ye, H., Chen, L. and Sutherland, IA. (2008) 'Intermittent counter-current extraction as an alternative approach to purification of chinese herbal medicine'.5th International Conference on Countercurrent Chromatography (CCC2008). Rio de Janeiro, Brazil. 26 - 29 July. [unpublished]

Conference paper

Hawes, D., Ignatova, SN., van den Heuvel, R. and Sutherland, IA. (2008) 'Non-synchronous preparative CCC - the next generation countercurrent centrifuge where phase separation and mixing can be independently controlled'.5th International Conference on Countercurrent Chromatography (CCC2008). Rio de Janeiro, Brazil. 26 - 29 July. [unpublished]

Conference paper

Ye, H., Ignatova, SN., Chen, L. and Sutherland, IA. (2008) 'Optimising resolution for a preparative separation of Chinese herbal medicine using a surrogate model sample system'.5th International Conference on Countercurrent Chromatography (CCC2008). Rio de Janeiro, Brazil. 26 - 29 July. [unpublished]

Conference paper

Ignatova, S., Wood, P., Hawes, D., Janaway, L., Keay, D. and Sutherland, I. (2007) 'Feasibility of scaling from pilot to process scale'. Journal of Chromatography A, 1151 (1-2). pp. 20 - 24. ISSN: 0021-9673

Journal article

Wood, P., Ignatova, S., Janaway, L., Keay, D., Hawes, D., Garrard, I. and et al. (2007) 'Counter-current chromatography separation scaled up from an analytical column to a production column'. Journal of Chromatography A, 1151 (1-2). pp. 25 - 30. ISSN: 0021-9673

Journal article