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Professor Amanda Harvey
Deputy Dean (Academic Affairs) / Professor - Biosciences

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Harvey, A., Burmi, R., Box, G., Wazir, U., Hussain, H., Davies, J., et al. (2022) 'Breast Tumour Kinase (Brk/PTK6) Contributes to Breast Tumour Xenograft Growth and Modulates Chemotherapeutic Responses In Vitro'. Genes, 13 (3). pp. 402 - 402. ISSN: 2073-4425 Open Access Link

Journal article

Bomer, M., Perez Salamo, I., Florance, H., Salmon, D., Dudenhoffer, J-H., Finch, P., et al. (2021) 'Jasmonates induce Arabidopsis bioactivities selectively inhibiting the growth of breast cancer cells through CDC6 and mTOR'. New Phytologist, 229 (4). pp. 2120 - 2134. ISSN: 0028-646X Open Access Link

Journal article

Houghton-Gisby, J. and Harvey, AJ. (2020) 'ACBD3, Its Cellular Interactors, and Its Role in Breast Cancer'. Cancer Studies and Therapeutics, 5 (2). pp. 1 - 7.Open Access Link

Journal article

Harvey, AJ. (2018) 'Overview of Cell Signaling Pathways in Cancer', in Badve, S. and Kumar, G. (eds.) Predictive Biomarkers in Oncology Applications in Precision Medicine. Cham, Switzerland : Springer. pp. 167 - 182. ISBN 10: 3319952277. ISBN 13: 978-3-319-95227-7. Open Access Link

Book chapter

Chudasama, D., Bo, V., Hall, M., Anikin, V., Jeyaneethi, J., Gregory, J., et al. (2017) 'Identification of novel cancer biomarkers of prognostic value using specific gene regulatory networks (GRN): a novel role of RAD51AP1 for ovarian and lung cancers'. Carcinogenesis, 39 (3). pp. 407 - 417. ISSN: 1460-2180 Open Access Link

Journal article

Linne, H., Yasaei, H., Marriott, A., Harvey, A., Mokbel, K., Newbold, R. and et al. (2017) 'Functional role of SETD2, BAP1, PARP-3 and PBRM1 candidate genes on the regulation of hTERT gene expression'. Oncotarget, 8 (37). pp. 61890 - 61900. ISSN: 1949-2553 Open Access Link

Journal article

Hare, SH. and Harvey, AJ. (2017) 'mTOR Function and Therapeutic Targeting in Breast Cancer'. American Journal of Cancer Research, 7 (3). pp. 383 - 404.Open Access Link

Journal article

Bourton, EC., Hussain, H., Plowman, PN., Harvey, AJ. and Parris, C. (2015) 'Radiosensitivity of Human Breast Cancer Cell Lines Expressing the Breast Tumor Kinase (Brk)'. Journal of Cancer Science and Therapy, 7 (3). pp. 95 - 101. ISSN: 1948-5956 Open Access Link

Journal article

Pires, IM., Blokland, NJG., Broos, AWT., Poujade, F-A., Senra, JM., Eccles, SA., et al. (2014) 'HIF-1α-independent hypoxia-induced rapid PTK6 stabilization is associated with increased motility and invasion'. Cancer Biology and Therapy, 15 (10). pp. 1350 - 1357. ISSN: 1538-4047 Open Access Link

Journal article

Mparmpakas, D., Zachariades, E., Sotiriadis, G., Goumenou, A., Harvey, AJ., Gidron, Y. and et al. (2014) 'Differential expression of placental glucocorticoid receptors and growth arrest-specific transcript 5 in term and preterm pregnancies: evidence for involvement of maternal stress'. Obstetrics and Gynecology International, 2014. pp. 1 - 10. ISSN: 1687-9589 Open Access Link

Journal article

Bridger, JM., Arican-Gotkas, HD., Foster, HA., Godwin, LS., Harvey, A., Kill, IR., et al. (2014) 'The non-random repositioning of whole chromosomes and individual gene loci in interphase nuclei and its relevance in disease, infection, aging, and cancer'. Advances in Experimental Medicine and Biology, 773. pp. 263 - 279. ISSN: 0065-2598 Open Access Link

Journal article

Hussain, HA. and Harvey, A. (2014) 'Evolution of breast cancer therapeutics: Breast tumour kinase’s role in breast cancer and hope for breast tumour kinase targeted therapy'. World Journal of Clinical Oncology, 5 (3). pp. 299 - 310. ISSN: 2218-4333 Open Access Link

Journal article

Harvey, A. (2013) 'Cancer Cell Signalling'. Wiley Blackwell. ISSN 13: 978-1-119-96756-9

Book

Harvey, A. (2013) 'Epidermal Growth Factor Receptor Family', in Harvey, AJ. (ed.) Cancer Cell Signalling. Wiley Blackwell. pp. 1 - 24. ISBN 13: 978-1-119-96757-6.

Book chapter

Thorpe, M., Shehu, E. and Harvey, A. (2013) 'Insulin and the insulin like growth factor (IGF) family', in Harvey, AJ. (ed.) Cancer Cell Signalling. Wiley Blackwell. pp. 25 - 43. ISBN 13: 978-1-119-96757-6.

Book chapter

Harvey, A. (2013) 'Signalling Cross Talk', in Harvey, AJ. (ed.) Cancer Cell Signalling. Wiley Blackwell. pp. 193 - 206. ISBN 13: 978-1-119-96757-6.

Book chapter

Eccles, SA., Eric O Aboagye, EO., Ali, S., Anderson, AS., Armes, J., Berditchevski, F., et al. (2013) 'Critical research gaps and translational priorities for the successful prevention and treatment of breast cancer'. Breast Cancer Research, 15 (5). pp. R92. ISSN: 1465-5411 Open Access Link

Journal article

Wazir, U., Sharma, AK., Mokbel, K., Ahmed, MH., Bridger, JM., Harvey, A. and et al. (2013) 'The clinicopathological significance of lamin A/C, lamin B1 and lamin B receptor mRNA expression in human breast cancer'. Cellular and Molecular Biology Letters, 18 (4). pp. 1 - 17. ISSN: 1425-8153 Open Access Link

Journal article

Bourton, EC., Foster, HA., Plowman, PN., Harvey, AJ. and Parris, CN. (2013) 'Hypersensitivity of BRCA1 Heterozygote Lymphoblastoid Cells to Gamma Radiation and PARP Inhibitors.'. J.Genet Syndr Gene Ther, 4 (5). pp. 146.Open Access Link

Journal article

Bourton, EC., Plowman, PN., Harvey, AJ., Adam Zahir, S. and Parris, CN. (2013) 'The PARP-1 inhibitor Olaparib causes retention of γ-H2AX foci in BRCA1 heterozygote cells following exposure to gamma radiation'. Journal of Cancer Therapy, 4 (11a). pp. 44 - 52. ISSN: 2151-1934 Open Access Link

Journal article

Harvey, AJ. (2012) 'Protein tyrosine kinase-6 (PTK6)', inEncyclopedia of Signaling Molecules. Springer. , 1. ISBN 10: 1441904603. ISBN 13: 978-1441904607.

Book chapter

Harvey, A. and Burmi, RS. (2011) 'Future therapeutic strategies: Implications for Brk targeting', in Gunduz, E. and Gundez, M. (eds.) Breast Cancer - Current and Alternative Therapeutic Modalities. InTech. ISBN 13: 978-953-307-776-5. Open Access Link

Book chapter

Tupper, J., Crompton, MR. and Harvey, AJ. (2011) 'Breast tumor kinase (Brk/PTK6) plays a role in the differentiation of primary keratinocytes'. Archives of Dermatological Research, 303 (4). pp. 293 - 297. ISSN: 0340-3696 Open Access Link

Journal article

Foster, H., Coley, HM., Goumenou, A., Pados, G., Harvey, A. and Karteris, E. (2010) 'Differential expression of mTOR signalling components in drug resistance in ovarian cancer'. Anticancer Research, 30 (9). pp. 3529 - 3534. ISSN: 0250-7005 Open Access Link

Journal article

Mehta, IS., Amira, M., Harvey, AJ. and Bridger, JM. (2010) 'Rapid chromosome territory relocation by nuclear motor activity in response to serum removal in primary human fibroblasts'. Genome Biology, 11 (1). pp. R5 - R5. ISSN: 1465-6906 Open Access Link

Journal article

Mparmpakas, D., Zachariades, E., Foster, H., Kara, A., Harvey, A., Goumenou, A. and et al. (2010) 'Expression of mTOR and downstream signalling components in the JEG-3 and BeWo human placental choriocarcinoma cell lines'. International Journal of Molecular Medicine, 25 (1). pp. 65 - 69. ISSN: 1791-244X Open Access Link

Journal article

Harvey, AJ., Pennington, CJ., Porter, S., Burmi, RS., Edwards, DR., Court, W., et al. (2009) 'Brk protects breast cancer cells from autophagic cell death induced by loss of anchorage'. American Journal of Pathology, 175 (3). pp. 1226 - 1234. ISSN: 0002-9440 Open Access Link

Journal article

Withey, JME., Harvey, AJ. and Crompton, MR. (2006) 'RNA interference targeting of Bcr-Abl increase chronic myeloid leukaemia cell killing by 17-allylamino-17-demethoxygeldanamycin.'. Leukaemia Research, 30 (5). pp. 553 - 560. ISSN: 0145-2126

Journal article

Cross, NA., Reid, SV., Harvey, AJ., Jokonya, N. and Eaton, CL. (2006) 'Opposing actions of TGFβ1 and FGF2 on growth and differentiation of prostatic stromal cells: Implications for benign prostatic hyperplasia progression'. Growth Factors, 24 (4). pp. 233 - 241. ISSN: 0897-7194

Journal article

Withey, JME., Marley, S., Kaeda, J., Harvey, AJ., Crompton, M. and Gordon, MY. (2005) 'Targeting primary human leukaemia cells with RNA interference: Bcr-Abl targeting inhibits myeloid progenitor self-renewal in chronic myeloid leukaemia cells.'. British Journal of Haematology, 129 (3). pp. 377 - 380. ISSN: 0007-1048

Journal article

Harvey, AJ. and Crompton, MR. (2004) 'The Brk protein tyrosine kinase as a therapeutic target in cancer: Opportunities and challenges'. Anti-Cancer Drugs, 15 (2). pp. 107 - 111. ISSN: 0959-4973

Journal article

Harvey, AJ. and Crompton, MR. (2003) 'Use of RNA interference to validate Brk as a novel therapeutic target in breast cancer: Brk promotes breast carcinoma cell proliferation'. Oncogene, 22 (32). pp. 5006 - 5010. ISSN: 0950-9232

Journal article

Bretland, AJ., Reid, SV., Chapple, CR. and Eaton, CL. (2001) 'Role of endogenous transforming growth factor β (TGFβ) 1 in prostatic stromal cells'. The Prostate, 48 (4). pp. 297 - 304. ISSN: 1097-0045

Journal article

Bretland, AJ., Lawry, J. and Sharrard, RM. (2001) 'A study of death by anoikis in cultured epithelial cells'. Cell Proliferation, 34 (4). pp. 199 - 210. ISSN: 1365-2184

Journal article

Klinger, HC., Bretland, AJ., Reid, SV., Chapple, CR. and Eaton, CL. (1999) 'Regulation of prostatic stromal cell growth and function by transforming growth factor beta (TGFβ)'. The Prostate, 41 (2). pp. 110 - 120. ISSN: 1097-0045

Journal article