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Mr Martin Scholze
Research Fellow

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Scholze, M., Taxvig, C., Kortenkamp, A., Boberg, J., Christiansen, S., Svingen, T., et al. (2020) 'Quantitative in Vitro to in Vivo Extrapolation (QIVIVE) for Predicting Reduced Anogenital Distance Produced by Anti-Androgenic Pesticides in a Rodent Model for Male Reproductive Disorders'. Environmental health perspectives, 128 (11). pp. 1 - 17. ISSN: 0091-6765 Open Access Link

Journal article

Martin, O., Scholze, M., Ermler, S., McPhie, J., Bopp, SK., Kienzler, A., et al. (2020) 'Ten years of research on synergisms and antagonisms in chemical mixtures: A systematic review and quantitative reappraisal of mixture studies'. Environment International, 146. pp. 106206 - 106206. ISSN: 0160-4120 Open Access Link

Journal article

Christiansen, S., Axelstad, M., Scholze, M., Johansson, HKL., Hass, U., Mandrup, K., et al. (2020) 'Grouping of endocrine disrupting chemicals for mixture risk assessment – Evidence from a rat study'. Environment International, 142 (September 2020). pp. 1 - 15. ISSN: 0160-4120 Open Access Link

Journal article

Lupu, D., Andersson, P., Bornehag, C-G., Demeneix, B., Fritsche, E., Gennings, C., et al. (2020) 'The endpoints project: Novel testing strategies for endocrine disruptors linked to developmental neurotoxicity'. International Journal of Molecular Sciences, 21 (11). pp. 1 - 16. ISSN: 1661-6596 Open Access Link

Journal article

Kortenkamp, A., Axelstad, M., Baig, AH., Bergman, Å., Bornehag, C-G., Cenijn, P., et al. (2020) 'Removing Critical Gaps in Chemical Test Methods by Developing New Assays for the Identification of Thyroid Hormone System-Disrupting Chemicals—The ATHENA Project'. International Journal of Molecular Sciences, 21 (9). pp. 1 - 11. ISSN: 1661-6596 Open Access Link

Journal article

Hamers, T., Kortenkamp, A., Scholze, M., Molenaar, D., Cenijn, PH. and Weiss, JM. (2020) 'Transthyretin-Binding Activity of Complex Mixtures Representing the Composition of Thyroid-Hormone Disrupting Contaminants in House Dust and Human Serum'. Environmental health perspectives, 128 (1). pp. 17015 - 17015. ISSN: 0091-6765 Open Access Link

Journal article

Kortenkamp, A., Faust, M., Backhaus, T., Altenburger, R., Scholze, M., Müller, C., et al. (2019) 'Mixture risks threaten water quality: the European Collaborative Project SOLUTIONS recommends changes to the WFD and better coordination across all pieces of European chemicals legislation to improve protection from exposure of the aquatic environment to multiple pollutants'. Environmental Sciences Europe, 31 (1). ISSN: 2190-4707

Journal article

Serra, H., Scholze, M., Altenburger, R., Busch, W., Budzinski, H., Brion, F. and et al. (2019) 'Combined effects of environmental xeno-estrogens within multi-component mixtures: Comparison of in vitro human- and zebrafish-based estrogenicity bioassays'. Chemosphere, 227. pp. 334 - 344. ISSN: 0045-6535 Open Access Link

Journal article

Ramhøj, L., Hass, U., Boberg, J., Scholze, M., Christiansen, S., Nielsen, F. and et al. (2018) 'Perfluorohexane sulfonate (PFHxS) and a mixture of endocrine disrupters reduce thyroxine levels and cause antiandrogenic effects in rats'. Toxicological Sciences, 163 (2). pp. 579 - 591. ISSN: 1096-6080 Open Access Link

Journal article

Altenburger, R., Scholze, M., Busch, W., Escher, BI., Jakobs, G., Krauss, M., et al. (2018) 'Mixture effects in samples of multiple contaminants – An inter-laboratory study with manifold bioassays'. Environment International, 114. pp. 95 - 106. ISSN: 0160-4120 Open Access Link

Journal article

Axelstad, M., Hass, U., Scholze, M., Christiansen, S., Kortenkamp, A. and Boberg, J. (2018) 'EDC IMPACT: Reduced sperm counts in rats exposed to human relevant mixtures of endocrine disrupters'. Endocrine Connections, 7 (1). pp. 139 - 148. ISSN: 2049-3614 Open Access Link

Journal article

Thrupp, TJ., Runnalls, TJ., Scholze, M., Kugathas, S., Kortenkamp, A. and Sumpter, JP. (2017) 'The consequences of exposure to mixtures of chemicals: Something from ‘nothing’ and ‘a lot from a little’ when fish are exposed to steroid hormones'. Science of the Total Environment, 619-620. pp. 1482 - 1492. ISSN: 0048-9697 Open Access Link

Journal article

Gaudriault, P., Mazaud-Guittot, S., Lavoué, V., Coiffec, I., Lesné, L., Dejucq-Rainsford, N., et al. (2017) 'Endocrine Disruption in Human Fetal Testis Explants by Individual and Combined Exposures to Selected Pharmaceuticals, Pesticides, and Environmental Pollutants'. Environmental Health Perspectives, 125 (8). pp. 087004 - 087004. ISSN: 0091-6765 Open Access Link

Journal article

Hass, U., Christiansen, S., Axelstad, M., Scholze, M. and Boberg, J. (2017) 'Combined exposure to low doses of pesticides causes decreased birth weights in rats'. Reproductive Toxicology, 72. pp. 97 - 105. ISSN: 0890-6238 Open Access Link

Journal article

Huerta, B., Margiotta-Casaluci, L., Rodríguez-Mozaz, S., Scholze, M., Winter, MJ., Barceló, D. and et al. (2016) 'Anti-anxiety drugs and fish behavior: Establishing the link between internal concentrations of oxazepam and behavioral effects'. Environmental Toxicology and Chemistry, 35 (11). pp. 2782 - 2790. ISSN: 0730-7268 Open Access Link

Journal article

Runnalls, TJ., Beresford, N., Kugathas, S., Margiotta-Casaluci, L., Scholze, M., Scott, AP. and et al. (2015) 'From single chemicals to mixtures-Reproductive effects of levonorgestrel and ethinylestradiol on the fathead minnow.'. Aquatic Toxicology, 169. pp. 152 - 167. ISSN: 1879-1514 Open Access Link

Journal article

Kugathas, S., Audouze, K., Ermler, S., Orton, F., Rosivatz, E., Scholze, M. and et al. (2015) 'Effects of common pesticides on prostaglandin D2 (PGD2) inhibition in SC5 mouse sertoli cells, evidence of binding at the cox-2 active site, and implications for endocrine disruption'. Environmental Health Perspectives, 124 (4). pp. 452 - 459. ISSN: 0091-6765 Open Access Link

Journal article

Evans, RM., Scholze, M. and Kortenkamp, A. (2015) 'Examining the feasibility of mixture risk assessment: A case study using a tiered approach with data of 67 pesticides from the Joint FAO/WHO Meeting on Pesticide Residues (JMPR)'. Food and Chemical Toxicology, 84. pp. 260 - 269. ISSN: 0278-6915 Open Access Link

Journal article

Arrebola, JP., Molina-Molina, JM., Fernández, MF., Sáenz, JM., Amaya, E., Indiveri, P., et al. (2015) 'A novel biomarker for anti-androgenic activity in placenta reveals risks of urogenital malformations'. Reproduction, 149 (6). pp. 605 - 613. ISSN: 1470-1626

Journal article

Green, C., Brian, J., Kanda, R., Scholze, M., Williams, R. and Jobling, S. (2015) 'Environmental concentrations of anti-androgenic pharmaceuticals do not impact sexual disruption in fish alone or in combination with steroid oestrogens'. Aquatic Toxicology, 160. pp. 117 - 127. ISSN: 0166-445X Open Access Link

Journal article

Orton, F., Ermler, S., Kugathas, S., Rosivatz, E., Scholze, M. and Kortenkamp, A. (2014) 'Mixture effects at very low doses with combinations of anti-androgenic pesticides, antioxidants, industrial pollutant and chemicals used in personal care products'. Toxicology and Applied Pharmacology, 278 (3). pp. 201 - 208. ISSN: 0041-008X Open Access Link

Journal article

Orton, F., Baynes, A., Clare, F., Duffus, ALJ., Larroze, S., Scholze, M. and et al. (2014) 'Body size, nuptial pad size and hormone levels: Potential non-destructive biomarkers of reproductive health in wild toads (Bufo bufo)'. Ecotoxicology, 23 (7). pp. 1359 - 1365. ISSN: 0963-9292

Journal article

Kortenkamp, A., Scholze, M. and Ermler, S. (2014) 'Mind the gap: Can we explain declining male reproductive health with known antiandrogens?'. Reproduction, 147 (4). pp. 515 - 527. ISSN: 1470-1626 Open Access Link

Journal article

Ermler, S., Scholze, M. and Kortenkamp, A. (2014) 'Genotoxic mixtures and dissimilar action: Concepts for prediction and assessment'. Archives of Toxicology, 88 (3). pp. 799 - 814. ISSN: 0340-5761 Open Access Link

Journal article

Scholze, M., Silva, E. and Kortenkamp, A. (2014) 'Extending the applicability of the dose addition model to the assessment of chemical mixtures of partial agonists by using a novel toxic unit extrapolation method'. PLoS ONE, 9 (2). pp. e88808 - e88808. ISSN: 1932-6203 Open Access Link

Journal article

Axelstad, M., Christiansen, S., Boberg, J., Scholze, M., Jacobsen, PR., Isling, LK., et al. (2014) 'Mixtures of endocrine-disrupting contaminants induce adverse developmental effects in preweaning rats'. Reproduction, 147 (4). pp. 489 - 501. ISSN: 1470-1626

Journal article

Martin, O., Kortenkamp, A. and Scholze, M. (2013) 'Safety factors in chemical risk assessment.'.Threshold of Toxicological Concern (TTC) for risk assessment of food contact material chemicals. Zurich, Switzerland. [unpublished]

Conference paper

Pottinger, TG., Katsiadaki, I., Jolly, C., Sanders, M., Mayer, I., Scott, AP., et al. (2013) 'Anti-androgens act jointly in suppressing spiggin concentrations in androgen-primed female three-spined sticklebacks - Prediction of combined effects by concentration addition'. Aquatic Toxicology, 140-141. pp. 145 - 156. ISSN: 0166-445X Open Access Link

Journal article

Altenburger, R., Backhaus, T., Boedeker, W., Faust, M. and Scholze, M. (2013) 'Simplifying complexity: Mixture toxicity assessment in the last 20 years'. Environmental Toxicology and Chemistry, 32 (8). pp. 1685 - 1687. ISSN: 0730-7268

Journal article

Martin, OV., Martin, S. and Andreas, K. (2013) 'Dispelling urban myths about default uncertainty factors in chemical risk assessment - Sufficient protection against mixture effects?'. Environmental Health: A Global Access Science Source, 12 (1). pp. 53. ISSN: 1476-069X Open Access Link

Journal article

Ermler, S., Scholze, M. and Kortenkamp, A. (2013) 'Seven benzimidazole pesticides combined at sub-threshold levels induce micronuclei in vitro'. Mutagenesis, 28 (4). pp. 417 - 426. ISSN: 0267-8357 Open Access Link

Journal article

Orton, F., Rosivatz, E., Scholze, M. and Kortenkamp, A. (2012) 'Competitive androgen receptor antagonism as a factor determining the predictability of cumulative antiandrogenic effects of widely used pesticides'. Environmental Health Perspectives, 120 (11). pp. 1578 - 1584. ISSN: 0091-6765 Open Access Link

Journal article

Evans, RM., Scholze, M. and Kortenkamp, A. (2012) 'Additive mixture effects of estrogenic chemicals in human cell-based assays can be influenced by inclusion of chemicals with differing effect profiles'. PLoS One, 7 (8). pp. e43606 - e43606. ISSN: 1932-6203 Open Access Link

Journal article

Westgarth-Smith, A., Roy, DB., Scholze, M., Tucker, A. and Sumpter, JP. (2012) 'The role of the North Atlantic Oscillation in controlling U.K. butterfly population size and phenology'. Ecological Entomology, 37 (3). pp. 221 - 232. ISSN: 0307-6946 Open Access Link

Journal article

Christiansen, S., Kortenkamp, A., Axelstad, M., Boberg, J., Scholze, M., Jacobsen, PR., et al. (2012) 'Mixtures of endocrine disrupting contaminants modelled on human high end exposures: An exploratory study in rats'. International Journal of Andrology, 35 (3). pp. 303 - 316. ISSN: 0105-6263

Journal article

Correia, AD., Cunha, SR., Scholze, M. and Stevens, ED. (2011) 'A novel behavioral fish model of nociception for testing analgesics'. Pharmaceuticals, 4 (4). pp. 665 - 680.Open Access Link

Journal article

Ermler, S., Scholze, M. and Kortenkamp, A. (2010) 'The sensitivity of the MDA-kb2 cell in vitro assay in detecting anti-androgenic chemicals - Identification of sources of variability and estimation of statistical power'. Toxicology in Vitro, 24 (6). pp. 1845 - 1853. ISSN: 0887-2333

Journal article

Christiansen, S., Dalgaard, M., Vinggaard, AM., Axelstad, M., Hass, U., Scholze, M. and et al. (2009) 'Synergistic disruption of external male sex organ development by a mixture of four antiandrogens'. Environmental Health Perspectives, 117 (12). pp. 1839 - 1846. ISSN: 0091-6765 Open Access Link

Journal article

Porsbring, T., Arrhenius, A., Backhaus, T., Kuylenstierna, M., Scholze, M. and Blanck, H. (2009) 'The SWIFT periphyton test for high-capacity assessments of toxicant effects on microalgal community development (vol 349, pg 295, 2007)'. JOURNAL OF EXPERIMENTAL MARINE BIOLOGY AND ECOLOGY, 373 (2). pp. 140 - 140. ISSN: 0022-0981

Journal article

Porsbring, T., Arrhenius, A., Backhaus, T., Kuylenstierna, M., Scholze, M. and Blanck, H. (2009) 'Corrigendum to "The SWIFT periphyton test for high-capacity assessments of toxicant effects on microalgal community development" [J. Exp. Mar. Biol. Ecol. 349 (2007) 295-98] (DOI:10.1016/j.jembe.2007.05.020)'. Journal of Experimental Marine Biology and Ecology, 373 (2). pp. 140. ISSN: 0022-0981

Journal article

Gonçalves, R., Scholze, M., Ferreira, AM., Martins, M. and Correia, AD. (2008) 'The joint effect of polycyclic aromatic hydrocarbons on fish behavior'. Environmental Research, 108 (2). pp. 205 - 213. ISSN: 0013-9351

Journal article

Christiansen, S., Scholze, M., Axelstad, M., Boberg, J., Kortenkamp, A. and Hass, U. (2008) 'Combined exposure to anti-androgens causes markedly increased frequencies of hypospadias in the rat'. International Journal of Andrology, 31 (2). pp. 241 - 248. ISSN: 0105-6263

Journal article

Porsbring, T., Arrhenius, A., Backhaus, T., Kuylenstierna, M., Scholze, M. and Blanck, H. (2007) 'The SWIFT periphyton test for high-capacity assessments of toxicant effects on microalgal community development'. Journal of Experimental Marine Biology and Ecology, 349 (2). pp. 299 - 312. ISSN: 0022-0981

Journal article

Correia, AD., Gonçalves, R., Scholze, M., Ferreira, M. and Henriques, MAR. (2007) 'Biochemical and behavioral responses in gilthead seabream (Sparus aurata) to phenanthrene'. Journal of Experimental Marine Biology and Ecology, 347 (1-2). pp. 109 - 122. ISSN: 0022-0981

Journal article

Metzdorff, SB., Dalgaard, M., Christiansen, S., Axelstad, M., Hass, U., Kiersgaard, MK., et al. (2007) 'Dysgenesis and histological changes of genitals and perturbations of gene expression in male rats after in utero exposure to antiandrogen mixtures'. Toxicological Sciences, 98 (1). pp. 87 - 98. ISSN: 1096-6080

Journal article

Brian, JV., Harris, CA., Scholze, M., Kortenkamp, A., Booy, P., Lamoree, M., et al. (2007) 'Evidence of estrogenic mixture effects on the reproductive performance of fish'. International Journal of Environmental Science and Technology, 41 (1). pp. 337 - 344. ISSN: 0013-936X Open Access Link

Journal article

Hass, U., Scholze, M., Christiansen, S., Dalgaard, M., Vinggaard, AM., Axelstad, M., et al. (2007) 'Combined exposure to anti-androgens exacerbates disruption of sexual differentiation in the rat'. Environmental Health Perspectives, 115 (SUPPL1). pp. 122 - 128. ISSN: 0091-6765 Open Access Link

Journal article

Kortenkamp, A., Faust, M., Scholze, M. and Backhaus, T. (2007) 'Low-level exposure to multiple chemicals: Reason for human health concerns?'. Environmental Health Perspectives, 115 (SUPPL1). pp. 106 - 114. ISSN: 0091-6765 Open Access Link

Journal article

Correia, AD., Freitas, S., Scholze, M., Gonçalves, J., Booij, P., Lamoree, MH., et al. (2007) 'Mixtures of estrogenic chemicals enhance vitellogenic response in sea bass'. Environmental Health Perspectives, 115 (SUPPL1). pp. 115 - 121. ISSN: 0091-6765 Open Access Link

Journal article

Silva, E., Scholze, M. and Kortenkamp, A. (2007) 'Activity of xenoestrogens at nanomolar concentrations in the E-screen assay'. Environmental Health Perspectives, 115 (SUPPL1). pp. 91 - 97. ISSN: 0091-6765 Open Access Link

Journal article