Waddington, SN., Nivsarkar, M., Mistry, A., Buckley, SMK., Kemball-Cook, G., Mosley, KL., Mitrophanous, K., Radcliffe, P., Holder, M., Brittan, M., Georgiadis, T., Al-Allaf, F., Bigger, B., Gregory, L., Cook, HT., Ali, RR., Thrasher, A., Tuddenham, EGD., Themis, M. and Coutelle, C. et al. (2004) 'Permanent phenotypic correction of Haemophilia B in immunocompetent mice by prenatal gene therapy'.1st Annual Conference of the British-Society-for-Gene-Therapy. Keble Coll, Oxford, ENGLAND. 28 - 30 March. WILEY-BLACKWELL. pp. S17 - S17. ISSN: 1099-498X

Nivsarkar, MS., Nathwani, A., Mosley, K., Davies, N., Gregory, LG., David, AL., Themis, M., Coutelle, C. and Waddington, SN. et al. (2004) 'Testosterone induced increase in transgene expression in vivo using Adenoviral Gene Delivery Vectors'.1st Annual Conference of the British-Society-for-Gene-Therapy. Keble Coll, Oxford, ENGLAND. 28 - 30 March. WILEY-BLACKWELL. pp. S12 - S13. ISSN: 1099-498X

Weisz, B., David, AL., Peebles, DM., Gregory, L., Perocheau, D., Themis, M., Terry, C., Coutelle, C. and Rodeck, CH. et al. (2004) 'Targeting the fetal gut for prenatal gene therapy.'.51st Annual Meeting of the Society-for-Gynecologic-Investigation. Houston, TX. 24 - 27 March. ELSEVIER SCIENCE INC. pp. 182A - 182A. ISSN: 1071-5576

Alison, MR., Vig, P., Russo, F., Bigger, BW., Amofah, E., Themis, M. and Forbes, S. et al. (2004) 'Hepatic stem cells: From inside and outside the liver?'. Cell Proliferation, 37 (1). pp. 1 - 21. ISSN: 0960-7722

Waddington, SN., Buckley, SMK., Gregory, LG., Themis, M., Coutelle, C. and Kennea, NL. (2004) 'Fetal and neonatal gene therapy: Benefits and pitfalls'.2nd European Conference and Practical Course on Towards Clinical Gene Therapy - Preclinical Gene Transfer Assessment. Univ Autonoma Barcelona, Fac Vet, Bellaterra, SPAIN. 1 - 14 February. Springer Science and Business Media LLC. pp. S92 - S97. ISSN: 0969-7128

Mellor, N., Themis, M., Selden, C., Jones, M. and Hodgson, HJF. (2004) 'Characteristics of murine histidinaemia and its potential for genetic manipulation'. Liver International, 24 (4). pp. 354 - 360. ISSN: 1478-3223

Peebles, D., Gregory, LG., David, A., Themis, M., Waddington, SN., Knapton, HJ., Miah, M., Cook, T., Lawrence, L., Nivsarkar, M., Rodeck, C. and Coutelle, C. et al. (2004) 'Widespread and efficient marker gene expression in the airway epithelia of fetal sheep after minimally invasive tracheal application of recombinant adenovirus in utero'. Gene Therapy, 11 (1). pp. 70 - 78. ISSN: 0969-7128

Themis, M., May, D., Coutelle, C. and Newbold, RF. (2003) 'Mutational effects of retrovirus insertion on the genome of V79 cells by an attenuated retrovirus vector: Implications for gene therapy'. Gene Therapy, 10 (19). pp. 1703 - 1711. ISSN: 0969-7128

David, AL., Peebles, DM., Gregory, L., Themis, M., Cook, T., Coutelle, C. and Rodeck, CH. et al. (2003) 'Percutaneous ultrasound-guided injection of the trachea in fetal sheep: A novel technique to target the fetal airways'. Fetal Diagnosis and Therapy, 18 (5). pp. 385 - 390. ISSN: 1015-3837

Waddington, SN., Mitrophanous, KA., Ellard, FM., Buckley, SM., Nivsarkar, M., Lawrence, L., Cook, HT., Al-Allaf, F., Bigger, B., Kingsman, SM., Coutelle, C. and Themis, M. et al. (2003) 'Long-term transgene expression by administration of a lentivirus-based vector to the fetal circulation of immuno-competent mice'. Gene Therapy, 10 (15). pp. 1234 - 1240. ISSN: 0969-7128

Azzouz, M., Le, TN., Waddington, S., Walmsley, L., Monani, U., Wilkes, FJ., Themis, M., Mitrophanous, KA., Burghes, A. and Mazarakis, ND. et al. (2003) 'Lentiviral vector-mediated gene therapy for a mouse model of spinal muscular atrophy'.6th Annual Meeting of the American-Society-of-Gene-Therapy. WASHINGTON, D.C. 4 - 8 June. ACADEMIC PRESS INC ELSEVIER SCIENCE. pp. S248 - S248. ISSN: 1525-0016

Themis, M., Waddington, S., Holder, M., Buckley, S., Mitrophanos, K., Bigger, B., Lawrence, L., Cook, T., Allaf, F., Kingsman, S., Coutelle, C. and Gregory, L. et al. (2003) 'Highly efficient and comprehensive gene transfer to all muscle groups necessary for the potential treatment of Duchenne/Becker muscular dystrophies following in utero delivery of a lentivirus vector in immuno-competent mice'.6th Annual Meeting of the American-Society-of-Gene-Therapy. WASHINGTON, D.C. 4 - 8 June. ACADEMIC PRESS INC ELSEVIER SCIENCE. pp. S320 - S320. ISSN: 1525-0016

Gregory, LG., Peebles, D., David, A., Themis, M., Waddington, SN., Knapton, HJ., Miah, M., Terry, C., Lawrence, L., Nivsarkar, M., Rodeck, C. and Coutelle, C. et al. (2003) 'Widespread and efficient adenovirus-mediated gene transfer to the airways by DEAE dextran and sodium caprate in adult mice and fetal sheep after minimally invasive tracheal application'.6th Annual Meeting of the American-Society-of-Gene-Therapy. WASHINGTON, D.C. 4 - 8 June. NATURE PUBLISHING GROUP. pp. S142 - S143. ISSN: 1525-0016

Buckley, SMK., Waddington, SN., Jezzard, S., Themis, M., Colledge, WH. and Coutelle, C. (2003) 'Intra-amniotic application of CFTR-expressing adenovirus does not reverse cystic fibrosis phenotype in inbred Cftr-knockout mice'.6th Annual Meeting of the American-Society-of-Gene-Therapy. WASHINGTON, D.C. 4 - 8 June. ACADEMIC PRESS INC ELSEVIER SCIENCE. pp. S200 - S200. ISSN: 1525-0016

Waddington, SN., Buckley, SMK., Cook, T., Gregory, L., Rahim, A., Nivsarkar, M., Themis, M., Bernloehr, C., Neubert, WJ., Lauer, UM., Coutelle, C. and Bitzer, M. et al. (2003) 'Fetal gene delivery using first and second generation Sendai virus'.6th Annual Meeting of the American-Society-of-Gene-Therapy. WASHINGTON, D.C. 4 - 8 June. ACADEMIC PRESS INC ELSEVIER SCIENCE. pp. S4 - S4. ISSN: 1525-0016

David, A., Cook, T., Waddington, S., Peebles, D., Nivsarkar, M., Knapton, H., Miah, M., Dahse, T., Noakes, D., Schneider, H., Rodec, C., Coutelle, C. and Themis, M. et al. (2003) 'Ultrasound-guided percutaneous delivery of adenoviral vectors encoding the β-galactosidase and human factor IX genes to early gestation fetal sheep In Utero'. Human Gene Therapy, 14 (4). pp. 353 - 364. ISSN: 1043-0342

Waddington, SN., Buckley, SMK., Nivsarkar, M., Jezzard, S., Schneider, H., Dahse, T., Kemball-Cook, G., Miah, M., Tucker, N., Dallman, MJ., Themis, M. and Coutelle, C. et al. (2003) 'In utero gene transfer of human factor IX to fetal mice can induce postnatal tolerance of the exogenous clotting factor'. BLOOD, 101 (4). pp. 1359 - 1366. ISSN: 0006-4971

Coutelle, C., Themis, M., Waddington, S., Gregory, L., Nivsarkar, M., Buckley, S., Cook, T., Rodeck, C., Peebles, D. and David, A. et al. (2003) 'The hopes and fears of in utero gene therapy for genetic disease - A review'.Symposium on From Genetics to Implantation and Early Fetal Development in Infertile Couples. MILAN, ITALY. 1 - 25 October. Elsevier BV. pp. S114 - S121. ISSN: 0143-4004

Grogory, LG., Harbotte, RP., Lawrence, L., Knapton, HJ., Themis, M. and Coutelle, C. (2003) 'Enhancement of adenovirus-mediated gene transfer to the airways by DEAE dextran and sodium caprate in vivo'. Molecular Therapy, 7 (1). pp. 19 - 26. ISSN: 1525-0016

Selden, C., Casbard, A., Themis, M. and Hodgson, HJF. (2003) 'Characterization of long-term survival of syngeneic hepatocytes in rat peritoneum'. Cell Transplantation, 12 (6). pp. 569 - 578. ISSN: 1555-3892

Ma, YL., Tolmachov, O., Themis, M., Poznansky, M., Coutelle, C. and Peters, NS. (2002) 'Enhanced gap-junctional coupling in connexin43 transduced skeletal myoblasts'.American-Heart-Association Abstracts From Scientific Sessions. CHICAGO, ILLINOIS. 17 - 20 November. LIPPINCOTT WILLIAMS & WILKINS. pp. 281 - 281. ISSN: 0009-7322

Ma, Y., Tolmacho, O., Themis, M., Poznansky, M., Coutelle, C. and Peters, NS. (2002) 'Intercellular communication in connexin43 transfected skeletal myocytes'.Congress of the European-Society-of-Cardiology. BERLIN, GERMANY. 31 - 4 September. W B SAUNDERS CO LTD. pp. 42 - 42. ISSN: 0195-668X

Eden, ER., Patel, DD., Sun, XM., Burden, JJ., Themis, M., Edwards, M., Lee, P., Neuwirth, C., Naoumova, RP. and Soutar, AK. et al. (2002) 'Restoration of LDL receptor function in cells from patients with autosomal recessive hypercholesterolemia by retroviral expression of ARH1'. Journal of Clinical Investigation, 110 (11). pp. 1695 - 1702. ISSN: 0021-9738

Tolmachov, O., Themis, M., Poznansky, M., Coutelle, C. and Peters, N. (2001) 'Construction of connexin 43 transducing retrovirus to produce electrocompetent skeletal muscle tissue for transplantation into the damaged heart'. European Heart Journal, 22. pp. 429 - 429. ISSN: 1522-9645

Chan, LMC., Coutelle, C. and Themis, M. (2001) 'A novel human suspension culture packaging cell line for production of high-titre retroviral vectors'. Gene Therapy, 8 (9). pp. 697 - 703. ISSN: 0969-7128

Coutelle, C., Themis, M., Schneider, H., Kiserud, T., Cook, T., Douar, AM., Hanson, M., Pavirani, A. and Rodeck, C. et al. (2001) 'Fetal somatic gene therapy--a preventive approach to the treatment of genetic disease: the case for.'.33rd Ernst-Schering-Research-Foundation Workshop. BERLIN, GERMANY. 1 Springer Berlin Heidelberg. pp. 99 - 114. ISSN: 0947-6075

Mellor, N., Themis, M., Selden, C., Jones, M. and Hodgson, HJ. (2000) 'Amelioration of murine histidinaemia using retroviral gene transfer'. Hepatology, 32 (4). pp. 182A - 182A. ISSN: 1527-3350

Schneider, H., Groves, M., Mühle, C., Reynolds, PN., Knight, A., Themis, M., Carvajal, J., Scaravilli, F., Curiel, DT., Fairweather, NF. and Coutelle, C. et al. (2000) 'Retargeting of adenoviral vectors to neurons using the Hc fragment of tetanus toxin'. Gene Therapy, 7 (18). pp. 1584 - 1592. ISSN: 0969-7128

Forbes, SJ., Themis, M., Alison, MR., Shiota, A., Kobayashi, T., Coutelle, C. and Hodgson, HJ. et al. (2000) 'Tri-iodothyronine and a deleted form of hepatocyte growth factor act synergistically to enhance liver proliferation and enable in vivo retroviral gene transfer via the peripheral venous system'. Gene Therapy, 7 (9). pp. 784 - 789. ISSN: 0969-7128

McKay, TR., MacVinish, LJ., Carpenter, B., Themis, M., Jezzard, S., Goldin, R., Pavirani, A., Hickman, ME., Cuthbert, AW. and Coutelle, C. et al. (2000) 'Selective in vivo transfection of murine biliary epithelia using polycation-enhanced adenovirus'. Gene Therapy, 7 (8). pp. 644 - 652. ISSN: 0969-7128

Forbes, SJ., Themis, M., Alison, MR., Sarosi, I., Coutelle, C. and Hodgson, HJ. (2000) 'Synergistic growth factors enhance rat liver proliferation and enable retroviral gene transfer via a peripheral vein'. Gastroenterology, 118 (3). pp. 591 - 598. ISSN: 0016-5085

Mellor, N., Themis, M., Selden, C. and Hodgson, HJ. (1999) 'An in-vitro model of histidinemia ameliorated by a histidase encoding retrovirus'. Hepatology, 30 (4). pp. 514A - 514A. ISSN: 1527-3350

Forbes, SJ., Fajinmi, MA., Themis, M., Alison, MR., Coutelle, C. and Hodgson, HH. (1999) 'Gene transfer to the carbon tetrachloride damaged rat liver in vivo with adenoviral and retroviral based vectors'. Hepatology, 30 (4). pp. 514A - 514A. ISSN: 1527-3350

Schneider, H., Adebakin, S., Themis, M., Cook, T., Douar, AM., Pavirani, A. and Coutelle, C. et al. (1999) 'Therapeutic Plasma Concentrations of Human Factor IX in Mice after Gene Delivery into the Amniotic Cavity: A Model for the Prenatal Treatment of Haemophilia B'. Journal of Gene Medicine, 1 (6). pp. 424 - 432. ISSN: 1099-498X

Themis, M., Schneider, H., Kiserud, T., Cook, T., Adebakin, S., Jezzard, S., Forbes, S., Hanson, M., Pavirani, A., Rodeck, C. and Coutelle, C. et al. (1999) 'Successful expression of β-galactosidase and factor IX transgenes in fetal and neonatal sheep after ultrasound-guided percutaneous adenovirus vector administration into the umbilical vein'. Gene Therapy, 6 (7). pp. 1239 - 1248. ISSN: 0969-7128

Themis, M., Forbes, SJ., Chan, L., Cooper, RG., Etheridge, CJ., Miller, AD., Hodgson, HJ. and Coutelle, C. et al. (1998) 'Enhanced in vitro and in vivo gene delivery using cationic agent complexed retrovirus vectors'. Gene Therapy, 5 (9). pp. 1180 - 1186. ISSN: 0969-7128

Forbes, SJ., Themis, M., Alison, MR., Selden, C., Coutelle, C. and Hodgson, HJF. (1998) 'Retroviral gene transfer to the liver in vivo during tri-iodothyronine induced hyperplasia'. Gene Therapy, 5 (4). pp. 552 - 555. ISSN: 0969-7128

Douar, AM., Adebakin, S., Themis, M., Pavirani, A., Cook, T. and Coutelle, C. (1997) 'Foetal gene delivery in mice by intra-amniotic administration of retroviral producer cells and adenovirus'. Gene Therapy, 4 (9). pp. 883 - 890. ISSN: 0969-7128

Douar, AM., Themis, M., Sandig, V., Friedmann, T. and Coutelle, C. (1996) 'Effect of amniotic fluid on cationic lipid mediated transfection and retroviral infection'. Gene Therapy, 3 (9). pp. 789 - 796. ISSN: 0969-7128

Douar, AM., Themis, M. and Coutelle, C. (1996) 'Fetal somatic gene therapy'. Molecular Human Reproduction, 2 (9). pp. 633 - 641. ISSN: 1360-9947

Trott, DA., Cuthbert, AP., Todd, CM., Themis, M. and Newbold, RF. (1995) 'Novel use of a selectable fusion gene as an "in-out" marker for studying genetic loss in mammalian cells'. Molecular Carcinogenesis, 12 (4). pp. 213 - 224. ISSN: 0899-1987

Cuthbert, AP., Trott, DA., Ekong, RM., Jezzard, S., England, NL., Themis, M., Todd, CM. and Newbold, RF. et al. (1995) 'Construction and characterization of a highly stable human:Rodent monochromosomal hybrid panel for genetic complementation and genome mapping studies'. Cytogenetics and Cell Genetics, 71 (1). pp. 68 - 76. ISSN: 0301-0171