Research projects Our research active academics are developing or furthering knowledge in health which can be implemented into practice or education. Below are some examples of the ground-breaking projects our academics have completed or are currently working on: Covid immunity passport service design Ongoing Does CRISPR-Cas9 treatment cause DNA damage in cancer cells? Ongoing Evolution of religious and secular medical treatments Ongoing Sustainable and healthy school food environments in Brazil Ongoing Pharmacological strategies for resolution of inflammation Ongoing Investigating thrombo-inflammation in disease Ongoing Manipulating our immune system to protect against ageing Ongoing Endocrine disruptors linked to developmental neurotoxicity Ongoing Improving the management of plastic packaging waste Completed Improving health in older adults by reducing sitting time Ongoing Mitigating plastic waste in Indonesia Ongoing Faith, difference and diversity in Muslim male prisoner rehabilitation Completed Common genetic variants that increase the risk of cancer Completed Radiation exposure and heritable genetic effects Ongoing Exploring the effectiveness of anti-doping interventions Ongoing The role of early growth protein molecules in preventing autoimmune disease and cancer Ongoing Metabolic reprogramming of skin microenvironment for improved BCG vaccine efficacy Completed Promoting inflammation resolution in sickle cell disease Ongoing The role of the oncoprotein MYB in the head and neck cancer adenoid cystic carcinoma Ongoing Determinants and mechanisms involved in alcohol consumption and its health consequences Completed Understanding the effects of inflammation on brain and behaviour Ongoing Generation of novel approaches for testing metabolism disrupting chemicals Ongoing Understanding of the mechanisms underlying adverse effects of pharmaceuticals Completed Understanding the effects of cyclo-oxygenase inhibition in the zebrafish Ongoing Investigating the dysfunction of the cerebral microvasculature in sickle cell disease Ongoing Innate immunity in bovine tuberculosis Completed Host-pathogen interactions in tuberculosis Ongoing Human endogenous factors in the control of mycobacterial infection Ongoing COVID-19 and Relationships Study Completed Protect mental health COVID-19 study Completed How do cells divide? Chromatin re-organisation from mitosis to G1 Ongoing Innovative polymer-based composite systems for high-efficient energy scavenging and storage Ongoing Investigating the role of CDCA2 molecule in neuroblastoma Ongoing Community sport and inequalities Ongoing Pandemic crisis prediction and management Ongoing Knowledge exchange on healthcare big data analytics Ongoing Reducing sitting behaviour in people with Type 2 diabetes Ongoing Attending mindfully: A psychophysiology study of sensory processing in meditators Ongoing Childhood maltreatment: emotional consequences and potential intervention Completed Air pollution, brain health and wellbeing in India Completed Mixed families in contemporary London Completed Elucidation of the metabolic signature of Friedreich's ataxia Completed Stealth marketing and physical activity Completed Community sport, wellbeing and mental health Completed Sport, Culture, Communities and Wellbeing Completed Breathing muscle strength in healthy children Completed Cytisine vs varenicline for smoking cessation in New Zealand Completed Addressing smokeless tobacco and building research capacity in South Asia (ASTRA) Completed Artificial intelligent system for oncological volumetric medical PET classification Completed 3D Software Mapping For Osteoarthritis Pain Self-Management Completed Supporting Patient-Practitioner Collaboration and Adherence via Mobile 3D Interior Design Technology Ongoing Retinal image analysis Ongoing The migration of social workers to and from the UK Completed Statistical modelling of multi-omics data Completed Diabetes UK: Understanding physical activity Completed Side effects of gene therapy vectors Completed New regression models for the analysis of well-being and income distribution Completed Health and well-being of adults with cerebral palsy Completed Innovative techniques for precise, atraumatic placement of cochlear implant (CI) Ongoing Modelling adenoid cystic carcinoma in a mouse Completed A new cell and gene therapy approach for Friedreich's ataxia Ongoing Scientific underpinnings of the clinical assessment of patellofemoral alignment Completed Biomechanical and sociological factors influencing pain and physical activity in children Completed Assessment of injury risk factors and mechanisms in elite netball Completed Vascular stiffness and distensibility in exercising humans Completed Optimising biomechanics of throwing performance Completed The impact of hydration status on heat acclimation adaptations Completed Circulating microvesicles responses to exercise and heat stress Completed Bike riding biomechanics and performance in children Completed Assessing the functional trajectories of people with chronic critical illness Completed Acute cardiovascular responses to slow and deep breathing Completed The impact of task complexity, cognitive load and anxiety on driving Completed The relationship between gaze and information pickup during action observation Completed The effects of sonification on motor imagery ability Completed Anticipation in Soccer Completed Road cycling behaviour of young adults Completed Improving services for electrically powered indoor/outdoor chair (EPIOC) users Completed Preclinical studies of the inherited disease Friedreich ataxia Completed Respiratory responses to exercise in athletes with spinal cord injury Completed Effects of creatine supplementation on the airways of youth elite football players Completed Medicines and diagnostics in Mozambique and Fiji Completed Physical activity and McArdle disease Ongoing Effects of dehydration and hyperthermia on brain and muscle blood flow Completed Injury Risk in Mixed Gender Football Completed Use of Liquid Biopsies as Cancer Biomarkers Completed Photographing Everyday Life: Ageing, Lived Experiences, Time and Space Completed Low-cost Portable Molecular Diagnostic Platform Ongoing RHOMBUS: Rehabilitation via HOMe Based gaming exercise for the Upper-limb post Stroke Completed Bloodwise Completed Safeguarding Quality or Papering over the cracks? Completed Built in a Day? Completed Over the top? Completed The Model Driven Hospitals Completed The Empty Taxi Completed Low-cost Diagnostic Platform for Detection of Poultry Infectious Pathogens Completed Evaluating the payback or impact from expenditure on research Completed The economics of public health Completed European-study on Quantifying Utility of Investment in Protection from Tobacco (EQUIPT) Completed Respiratory physiology, human performance and health Completed The clinical and cost-effectiveness of different treatment pathways for neuropathic pain Completed MESOVATS trial Completed Economic and Psychological Evaluation of the Multi-Centre Aneurysm Screening study (MASS) Completed Screening Women for Aneurysms (SWAN) Completed Economic issues associated with operation and Evaluation of Telemedicine Services Completed The growth and rupture rate of small abdominal aortic aneurysms- implication for screening Completed An Economic Evaluation of Telemedicine to Provide Specialist Advice in Paediatric Cardiology (The TelePaed Project) Completed The cost effectiveness of genetic markers for antibiotic resistance in tuberculosis Completed Assessment Evaluation of the Health Economics of Anti- Depressants (AHEAD) Completed Collaboration with Papworth Hospital Completed Evaluation of the national strain typing service for tuberculosis Completed Improving Patient Choice in Treating Low Back Pain (IMPACT - LBP) Completed Economic evaluation of non-invasive tests of fibrosis and cirrhosis Completed Sport and Employability Completed Shadows of the Dawn: Migration and the Indeterminacy of Community and Immunity Completed Preventing Inter-faith relations in Israel through social services and the media Completed Culture, Sport and Wellbeing: Social Diversity and Context Matters Completed The Health and Sport Engagement (HASE) Project Completed Physical Activity in the Workplace Completed Cancer and physical activity Completed Muscle response to exercise in cerebral palsy Completed Daiwa Foundation sponsored project with Tokyo University Completed Drug rescue of frataxin-dependent neural and cardiac pathophysiology in FA Completed Robotic surgery and society Completed GAP WORK: Improving gender-related violence intervention and referral through youth practitioner training Completed Universities Supporting Victims of Sexual Violence Completed Microfluidics in Diagnosis Completed Modelling infant leukaemia using gene editing technology Completed Strength Training for Adolescents with cerebral palsy (STAR) Completed Protein Phosphatase 1 (PP1) in the Regulation of Mitotic Exit and Nuclear Organisation Completed Developing the International Safeguards for Children in Sport Completed Muscle heat shock proteins with passive heating Completed Ageing, Communication, Technologies (ACT): experiencing a digital world in later life Completed Public Communication of Environmental and Health Risks Completed Exploring the Potential of Disabled Comedians in Improving the Lives and Experiences of Disabled People Completed Stem cell mitotic response to damage in old and young Drosophila melanogaster Completed Photographing Everyday Life: Ageing, Lived Experiences, Time and Space Completed Why aren't all old people lonely? A comparative analysis of European Union Completed The wellbeing needs of older people living with sight loss Completed Living Well with Dementia (IDEAL) Completed What Works Wellbeing: Culture, Sport and Wellbeing Evidence Review: Social Diversity and Context Matters Completed Dare to Age Well Completed Tackling Ageing Continence through Theory, Tools and Technology (TACT3) Completed Development of a web-based decision aid to assist occupational therapists to make optimal fitness-to-drive decisions for disabled and older drivers Completed Pelvic floor exercise device for prevention and cure of Stress Urinary Incontinence in women Completed Scoping our future research priorities Completed Give and Take Care Completed New perspectives on loneliness: developing theory, methodology and evidence practice Completed Hydration and human cardiovascular function Completed Chromosome dynamics and Nuclear Motors – Chromobility Completed Cytogenetic Assessment of British Nuclear Test Veterans and their Offspring Completed Understanding and Treatment of Hutchinson-Gilford Progeria Syndrome Completed Evaluation of oligonucleotides for therapy of Friedreich ataxia Completed Social cash transfers, generational relations and youth poverty trajectories in rural Lesotho and Malawi Completed