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Dr Sibylle Ermler

Dr Sibylle Ermler
Research Fellow

Halsbury Building 132

Research area(s)

Research Activities:

My current research focuses on the effects of endocrine disrupting chemicals on adipogenesis. My aim is to elucidate how environmental exposures can lead to metabolic disorders such as obesity and which role different fat compartments, such as white and brown adipose tissues may play. In addition, my research interests are in the toxicology of chemical mixtures, the implications of mixture effects for human health and how mixture toxicology impacts on the need for cumulative risk assessment of chemical substances. In the past, I have also investigated the combined effects of genotoxic compounds with focus on aneugenic benzimidazole pesticides but also including agents which act via other modes of action. Furthermore, I studied the mixture effects of environmental and food contaminants that act as endocrine disruptors, in particular anti-antiandrogens and estrogens. I am interested in the hypothesis that cumulative exposure to environmental endocrine disruptors and other compounds contributes to the development of human diseases, such as obesity and cancer.

Research grants and projects

Research Projects

Grants

Data collection in support of the Endocrine Disruption (ED) assessment for non-target vertebrates
Funder: European Food Safety Authority
Duration: February 2019 - February 2020
Systematic Literature Review on Interactions in Chemical Mixtures
Funder: European Joint Research Centre
Duration: January 2018 - December 2018