Sibylle Ermler is a Research Fellow in Human Toxicology in the Department of Life Sciences. She has expertise in the impact of endocrine disrupting chemicals (EDCs) and genotoxicants on human and environmental health. Her research interests are in male and female reproductive health, metabolic disorders, and the developmental origins of health and disease. Furthermore, she is an expert in mixture toxicology with an interest in the translation of (mixture-) toxicology into chemical risk assessment. Sibylle’s research has a focus on the development and application of novel in vitro approaches with the aim of creating human relevant models for human disease, and reducing the requirement for animal testing. Additional interdisciplinary research interests include the impact of climate change on food systems and on human development and health.
2011-present: Research Fellow, Institute of Environment, Health and Societies, Brunel University
2007-2011: Postdoctoral Research Fellow, Centre for Toxicology, School of Pharmacy, London
2006: Dr. rer. nat. (PhD) Faculty of Biosciences, Ruperto-Carola University, Heidelberg, Thesis title: “The Role of the Telomeric Repeat Binding Factor 2 (TRF2) in Normal and Tumour Cells”, conducted at the German Cancer Research Center, Heidelberg, Germany
2001: Diploma in environmental and chemical engineering/biotechnology, Fachhochschule Furtwangen, Germany Dissertation title: “Development of a Genotoxicity Assay for High Throughput Screening”, conducted at the University of Manchester Institute of Science and Technology, Manchester, UK Awarded with the “Aesculap prize for a particularly innovative diploma thesis at the University of Applied Sciences Furtwangen with an industry-relevant topic“
2021-present : Researchers Senate Representative
Newest selected publications
Poore, K., Pedersen, M. and Ermler, S. (2022) 'Environmental Exposures in Early Life: Effects of Air Pollution, Chemicals and Climate Change on Human Health and Wellbeing', in Poston, L., Godfrey, K., Gluckman, SP. and Hanson, M. (eds.) Developmental Origins of Health and Disease. Cambridge : Cambridge University Press. , [2nd ed.]. pp. 56 - 65. ISBN 10: 1-009-27225-X. ISBN 13: 978-1-009-27225-4.
Ermler, S. and Kortenkamp, A. (2022) 'Systematic review of associations of polychlorinated biphenyl (PCB) exposure with declining semen quality in support of the derivation of reference doses for mixture risk assessments'. Environmental Health, 21 (1). pp. 94. ISSN: 1476-069X Open Access Link
Kortenkamp, A., Scholze, M., Ermler, S., Priskorn, L., Jørgensen, N., Andersson, A-M. and (2022) 'Combined exposures to bisphenols, polychlorinated dioxins, paracetamol, and phthalates as drivers of deteriorating semen quality'. Environment International, 165. pp. 1 - 14. ISSN: 0160-4120 Open Access Linket al.
Ermler, S. and Kortenkamp, A. (2022) 'Declining semen quality and polybrominated diphenyl ethers (PBDEs): Review of the literature to support the derivation of a reference dose for a mixture risk assessment'. International Journal of Hygiene and Environmental Health, 242. pp. 1 - 10. ISSN: 1438-4639 Open Access Link
Kortenkamp, A., Martin, O., Ermler, S., Baig, A. and Scholze, M. (2022) 'Bisphenol A and declining semen quality: A systematic review to support the derivation of a reference dose for mixture risk assessments'. International Journal of Hygiene and Environmental Health, 241. pp. 113942 - 113942. ISSN: 1438-4639 Open Access Link