Sibylle Ermler is a Research Fellow in Human Toxicology in the Department of Life Sciences. She has expertise in the impact of endocrine disrupting chemicals (EDCs) and genotoxicants on human and environmental health. Her research interests are in male and female reproductive health, metabolic disorders, and the developmental origins of health and disease. Furthermore, she is an expert in mixture toxicology with an interest in the translation of (mixture-) toxicology into chemical risk assessment. Sibylle’s research has a focus on the development and application of novel in vitro approaches with the aim of creating human relevant models for human disease, and reducing the requirement for animal testing. Additional interdisciplinary research interests include the impact of climate change on food systems and on human development and health.
2011-present: Research Fellow, Institute of Environment, Health and Societies, Brunel University
2007-2011: Postdoctoral Research Fellow, Centre for Toxicology, School of Pharmacy, London
2006: Dr. rer. nat. (PhD) Faculty of Biosciences, Ruperto-Carola University, Heidelberg, Thesis title: “The Role of the Telomeric Repeat Binding Factor 2 (TRF2) in Normal and Tumour Cells”, conducted at the German Cancer Research Center, Heidelberg, Germany
2001: Diploma in environmental and chemical engineering/biotechnology, Fachhochschule Furtwangen, Germany Dissertation title: “Development of a Genotoxicity Assay for High Throughput Screening”, conducted at the University of Manchester Institute of Science and Technology, Manchester, UK Awarded with the “Aesculap prize for a particularly innovative diploma thesis at the University of Applied Sciences Furtwangen with an industry-relevant topic“
2021-present : Researchers Senate Representative
Newest selected publications
Kortenkamp, A., Scholze, M., Ermler, S., Priskorn, L., Jørgensen, N., Andersson, A-M. and (2022) 'Combined exposures to bisphenols, polychlorinated dioxins, paracetamol, and phthalates as drivers of deteriorating semen quality'. Environment International. pp. 107322 - 107322. ISSN: 0160-4120et al.
Ermler, S. and Kortenkamp, A. (2022) 'Declining semen quality and polybrominated diphenyl ethers (PBDEs): Review of the literature to support the derivation of a reference dose for a mixture risk assessment'. International Journal of Hygiene and Environmental Health, 242. pp. 1 - 10. ISSN: 1438-4639 Open Access Link
Kortenkamp, A., Martin, O., Ermler, S., Baig, A. and Scholze, M. (2022) 'Bisphenol A and declining semen quality: A systematic review to support the derivation of a reference dose for mixture risk assessments'. International Journal of Hygiene and Environmental Health, 241. pp. 113942 - 113942. ISSN: 1438-4639 Open Access Link
Kassotis, CD., Hoffman, K., Völker, J., Pu, Y., Veiga-Lopez, A., Kim, SM., (2021) 'Reproducibility of adipogenic responses to metabolism disrupting chemicals in the 3T3-L1 pre-adipocyte model system: An interlaboratory study'. Toxicology, 461. pp. 1 - 12. ISSN: 0300-483X Open Access Linket al.
Scholze, M., Taxvig, C., Kortenkamp, A., Boberg, J., Christiansen, S., Svingen, T., (2020) 'Quantitative in Vitro to in Vivo Extrapolation (QIVIVE) for Predicting Reduced Anogenital Distance Produced by Anti-Androgenic Pesticides in a Rodent Model for Male Reproductive Disorders'. Environmental health perspectives, 128 (11). pp. 1 - 17. ISSN: 0091-6765 Open Access Linket al.