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Respiratory responses and limitations to exercise

The aim of this project is to determine how healthy ageing influences the dynamic contractile properties of the respiratory muscles. Using advanced assessment techniques, we will comprehensively evaluate inspiratory and expiratory muscle function in older and younger adults. Specifically, the project will examine how dynamic contractile parameters vary with age, sex and physical activity, and will explore their associations with exertional dyspnoea, exercise capacity and quality of life. We hypothesise that while respiratory muscle strength is relatively well preserved with healthy ageing, there are pronounced age-related impairment in contractile dynamics that contribute to increased fatigability and functional limitation. The findings will advance mechanistic understanding of respiratory muscle function with ageing and guide the development of interventions to preserve respiratory health in older populations.

How to apply

If you are interested in applying for the above PhD topic please follow the steps below:

  1. Contact the supervisor by email or phone to discuss your interest and find out if you would be suitable. Supervisor details can be found on this topic page. The supervisor will guide you in developing the topic-specific research proposal, which will form part of your application.
  2. Click on the "Apply here" button on this page and you will be taken to the relevant PhD course page, where you can apply using an online application.
  3. Complete the online application indicating your selected supervisor and include the research proposal for the topic you have selected.

Good luck!

This is a self funded topic

Brunel offers a number of funding options to research students that help cover the cost of their tuition fees, contribute to living expenses or both. See more information here.

The UK Government is also offering Doctoral Student Loans for eligible students, and there is some funding available through the Research Councils.

Many of our international students benefit from funding provided by their governments or employers. Brunel alumni enjoy tuition fee discounts of 15%.

Meet the Supervisor

Lee Romer

Dr Romer holds a Readership in Human and Applied Physiology. After completing undergraduate and postgraduate studies at Brunel, he worked for several years at the British Olympic Medical Centre where he was responsible for the design, management and provision of physiological support services to Olympic Governing Bodies. He completed a PhD at the University of Birmingham and received post-doctoral training at the John Rankin Laboratory of Pulmonary Medicine, University of Wisconsin-Madison, USA. He rejoined Brunel in 2004, serving as Division Lead from 2014 to 2018.