Human Toxicology and Risk Assessment
The research in the Human Toxicology and Risk Assessment group falls into two broad themes:
Dealing with cocktail effects in chemicals regulation and risk assessment
Traditional chemicals risk assessment has a quite artificial orientation: It treats chemicals as if they act in isolation, when in reality there is exposure to multiple substances. We have developed ways of improving chemical risk assessment by taking “cocktail effects” into account. Following 15 years of research led by Prof. Andreas Kortenkamp, our work is beginning to influence European Union chemicals regulation, particularly in the area of pesticides and endocrine disrupters.
Hormones and human cancers
Hormones play a role in cancers of the breast, prostate and testes, but how precisely they influence the disease process remains unclear. Our research aims at elucidating the role that hormones and hormone-like chemicals play in cellular and tissue maintenance, carcinogenesis and tumour progression. Dr. Elisabete Silva is developing three dimensional breast epithelial cell culture systems for the study of signalling processes.
See also: MSc in Toxicology and Risk Assessment