PhD topics for research students

Find below a list of currently available self-funded PhD topics.

We encourage all students to contact the supervisor or the alternative contact person for more information and an informal chat to discuss the process of applying and preparing your research statement. For more information on how to apply click here.

Description
Supervisor
Funding
Developing RAC1B-targeting therapies to improve the treatment outcomes for breast cancer
In this project, transgenic reporter cell lines, which will be generated using CRISPR-mediated gene editing, will be used to screen large drug libraries along with functional assays to analyse breast ...
Self Funded
Hypoxia-driven macrophage modulation in cancer and its impact on T cell immunotherapy
Hypoxia is a common feature of solid tumours. It presents a significant challenge to effective cancer treatment using immunotherapy. Macrophages are known to be recruited to hypoxic regions of the tum...
Self Funded
Development of a novel PCR-based assay to evaluate CAR-T safety using a human-based genotoxicity model
The project on offer is to develop a model for the evaluation of safety when using immunotherapy. CAR-T therapy is currently a novel approach to treat cancer using T cells infected by lentivirus vecto...
Self Funded
3D printing of scaffolds for tissue engineering and regenerative medicine
This project aims to develop multifunctional novel bioactive tissue scaffolds using 3D printing, biomaterials science and controlled drug delivery systems to enhance tissue regeneration. Tissue scaffo...
Self Funded
The role of PE/PPE proteins in tuberculosis
Tuberculosis remains one of the world’s biggest killers due to an infectious disease. There remains an urgent need for the development of effective vaccines and novel drug targets against the disease....
Self Funded
Development of a miniature capsule robot for capsule endoscopy
A capsule robot has potential applications in medical diagnosis (e.g. capsule endoscopy) and treatments. In 2000, Given Imaging introduced the capsule endoscope which has many advantages over the trad...
Self Funded
Health data analysis to identify the role of gene and environment in risk of cardiovascular diseases
Main Aim: To identify the role of environment and genes in risk of cardiovascular disease Cardiovascular diseases including hypertension, myocardial infarction, heart failure, and stroke are the leadi...
Self Funded