
Dr Ronan Mccarthy
Reader in Biomedical Sciences
Heinz Wolff 130
- Email: ronan.mccarthy@brunel.ac.uk
- Tel: +44 (0)1895 268441
Summary
Ronan gained his Bachelor of Science in Genetics with first class honours from University College Cork, Ireland in 2010 and was awarded the title of College Scholar. In autumn 2010, Ronan was awarded an Irish Research Council PhD Scholarship to study novel biofilm inhibition strategies against the opportunistic pathogen Pseudomonas aeruginosa in the lab of Professor Fergal O’Gara. In 2014, Ronan joined the research group of Professor Alain Filloux at the MRC Centre for Bacteriology and Infection at Imperial College London. As a Postdoctoral Research Associate, Ronan interrogated the second messenger signalling cascades that govern the biofilm mode of growth in Pseudomonas aeruginosa and Agrobacterium tumefaciens. Following on from his time at Imperial College Ronan joined the Microbiology Department at the Animal and Plant Health Agency where he used host transcriptomics and pathway analysis to profile the host response to infection. He joined the Biosciences Division in Brunel University to continue his analysis of the regulatory networks that govern pathogenicity, antimicrobial resistance and biofilm formation in the Gram negative opportunistic pathogens Pseudomonas aeruginosa and Acinetobacter baumannii. In 2021, Ronan was awarded a BBSRC New Investigator Award to study the regulation of desiccation tolerance and biofilm formation in Acinetobacter baumannii and to identify compounds that could disrupt these survival mechanisms.
Responsibility
BB2716- Medical Microbiology- Lecturer
BB2802- Primary Literature Interrogation and Synthesis
Newest selected publications
Proctor, CR., Taggart, MG., O'Hagan, BMG., McCarron, PA., McCarthy, RR. and Ternan, NG. (2023) 'Furanone loaded aerogels are effective antibiofilm therapeutics in a model of chronic Pseudomonas aeruginosa wound infection'. Biofilm, 5. pp. 1 - 10. ISSN: 2590-2075 Open Access Link
McCarthy, RR., Proctor, CR., Kim, H. and Walker, D. (2023) 'Understanding the consumption of antimicrobial resistance related content on Social Media: Twitter Analysis'. Journal of Medical Internet Research, 0 (accepted, in press). pp. 1 - 20. ISSN: 1439-4456 Open Access Link
de Dios, R., Proctor, CR., Maslova, E., Dzalbe, S., Rudolph, CJ. and McCarthy, RR. (2022) 'Artificial sweeteners inhibit multidrugāresistant pathogen growth and potentiate antibiotic activity'. EMBO Molecular Medicine, 15 (1). pp. 1 - 21. ISSN: 1757-4676 Open Access Link
de Dios, R., Gadar, K. and McCarthy, RR. (2022) 'A high-efficiency scar-free genome editing toolkit for Acinetobacter baumannii'. Journal of Antimicrobial Chemotherapy, 77 (12). pp. 3390 - 3398. ISSN: 0305-7453 Open Access Link
Arroyo-Moreno, S., Cummings, M., Corcoran, DB., Coffey, A. and McCarthy, RR. (2022) 'Identification and characterization of novel endolysins targeting Gardnerella vaginalis biofilms to treat bacterial vaginosis'. npj Biofilms and Microbiomes, 8 (1). pp. 1 - 12. ISSN: 2055-5008 Open Access Link