Ronan gained his Bachelor of Science in Genetics with first class honours from University College Cork, Ireland in 2010 and was awarded the title of College Scholar. In autumn 2010, Ronan was awarded an Irish Research Council PhD Scholarship to study novel biofilm inhibition strategies against the opportunistic pathogen Pseudomonas aeruginosa in the lab of Professor Fergal O’Gara. In 2014, Ronan joined the research group of Professor Alain Filloux at the MRC Centre for Bacteriology and Infection at Imperial College London. As a Postdoctoral Research Associate, Ronan interrogated the second messenger signalling cascades that govern the biofilm mode of growth in Pseudomonas aeruginosa and Agrobacterium tumefaciens. Following on from his time at Imperial College Ronan joined the Microbiology Department at the Animal and Plant Health Agency where he used host transcriptomics and pathway analysis to profile the host response to infection. In 2018, he joined the Biosciences Division in Brunel University to continue his analysis of interactions at the host pathogen interface.
BB2716- Medical Microbiology- Lecturer
BB2802- Primary Literature Interrogation and Synthesis
Newest selected publications
Gutiérrez-Barranquero, JA., Reen, FJ., Parages, ML., McCarthy, R., Dobson, ADW. and O'Gara, F. (2017) 'Disruption of N -acyl-homoserine lactone-specific signalling and virulence in clinical pathogens by marine sponge bacteria'. Microbial Biotechnology. ISSN: 1751-7915 Open Access Link
McCarthy, RR., Mazon-Moya, MJ., Moscoso, JA., Hao, Y., Lam, JS., Bordi, C., (2017) 'Cyclic-di-GMP regulates lipopolysaccharide modification and contributes to Pseudomonas aeruginosa immune evasion'. Nature Microbiology, 2 (6). pp. 17027 - 17027. ISSN: 2058-5276 Open Access Linket al.
McCarthy, RR., Valentini, M. and Filloux, A. (2017) 'Contribution of Cyclic di-GMP in the Control of Type III and Type VI Secretion in Pseudomonas aeruginosa.'. Methods in molecular biology (Clifton, N.J.), 1657. pp. 213 - 224. ISSN: 1064-3745
Larrouy-Maumus, G., Clements, A., Filloux, A., McCarthy, RR. and Mostowy, S. (2015) 'Direct detection of lipid A on intact Gram-negative bacteria by MALDI-TOF mass spectrometry'. Journal of Microbiological Methods, 120. pp. 68 - 71. ISSN: 0167-7012 Open Access Link
Gutiérrez-Barranquero, JA., Reen, FJ., McCarthy, RR. and O’Gara, F. (2015) 'Deciphering the role of coumarin as a novel quorum sensing inhibitor suppressing virulence phenotypes in bacterial pathogens'. Applied Microbiology and Biotechnology, 99 (7). pp. 3303 - 3316. ISSN: 0175-7598