Steven obtained a B.Sc. in Medical Sciences from the University of Leeds and received a Ph.D. for a project at the Cancer Medicine Research Unit at St. James's University Hospital, Leeds, investigating the CD8 T-cell stimulating properties of a DNA vaccine encoding multiple, melanoma-associated epitopes. Following a post-doctoral position at the Edward Jenner Institute for Vaccine Research in which he examined the role of auto-reactive CD8 T-cells and T-cell regulation in the context of joint inflammation, he joined the group of Prof. Hazel Dockrell at the London School of Hygiene and Tropical Medicine where he investigated the cellular immune response to BCG vaccination and more generally with immune mechanisms that might provide protection against tuberculosis infection and disease. Steven joined the Division of Biosciences in January 2020.
Newest selected publications
Lee, H., Kim, J., Kang, YA., Kim, DR., Sim, B., Zelmer, A., (2019) 'In vitro Mycobacterial Growth Inhibition in South Korean Adults With Latent TB Infection'. Frontiers in Immunology, 10 (APR). pp. 896. ISSN: 1664-3224 Open Access Linket al.
Tanner, R., Smith, SG., van Meijgaarden, KE., Giannoni, F., Wilkie, M., Gabriele, L., (2019) 'Optimisation, harmonisation and standardisation of the direct mycobacterial growth inhibition assay using cryopreserved human peripheral blood mononuclear cells'. Journal of Immunological Methods, 469. pp. 1 - 10. ISSN: 0022-1759 Open Access Linket al.
O’Shea, MK., Tanner, R., Müller, J., Harris, SA., Wright, D., Stockdale, L., (2018) 'Immunological correlates of mycobacterial growth inhibition describe a spectrum of tuberculosis infection'. Scientific Reports, 8 (1). pp. 14480. ISSN: 2045-2322 Open Access Linket al.
Hasso-Agopsowicz, M., Scriba, TJ., Hanekom, WA., Dockrell, HM. and Smith, SG. (2018) 'Differential DNA methylation of potassium channel KCa3.1 and immune signalling pathways is associated with infant immune responses following BCG vaccination'. Scientific Reports, 8 (1). pp. 13086. ISSN: 2045-2322 Open Access Link
Smith, SG., Kleinnijenhuis, J., Netea, MG. and Dockrell, HM. (2017) 'Whole Blood Profiling of Bacillus Calmette–Guérin-Induced Trained Innate Immunity in Infants Identifies Epidermal Growth Factor, IL-6, Platelet-Derived Growth Factor-AB/BB, and Natural Killer Cell Activation'. Frontiers in Immunology, 8. pp. 644. ISSN: 1932-6203 Open Access Link