Dr Steven Smith
Senior Lecturer in Biomedical Sciences
Heinz Wolff 132
- Email: steven.smith@brunel.ac.uk
- Tel: +44 (0)1895 268956
Summary
Steven obtained a B.Sc. in Medical Sciences from the University of Leeds and received a Ph.D. for a project at the Cancer Medicine Research Unit at St. James's University Hospital, Leeds, investigating the CD8 T-cell stimulating properties of a DNA vaccine encoding multiple, melanoma-associated epitopes. Following a post-doctoral position at the Edward Jenner Institute for Vaccine Research in which he examined the role of auto-reactive CD8 T-cells and T-cell regulation in the context of joint inflammation, he joined the group of Prof. Hazel Dockrell at the London School of Hygiene and Tropical Medicine where he investigated the cellular immune response to BCG vaccination and more generally with immune mechanisms that might provide protection against tuberculosis infection and disease. Steven joined the Division of Biosciences in January 2020.
Qualifications
B.Sc. (Hons)
Ph.D.
FHEA
Newest selected publications
Smith, SG., Bowness, R. and Cliff, JM. (2025) 'Host-directed therapy in diabetes and tuberculosis comorbidity toward global tuberculosis elimination'. International Journal of Infectious Diseases, 155. pp. 1 - 8. ISSN: 1201-9712 Open Access Link
Musvosvi, M., Huang, H., Wang, C., Xia, Q., Rozot, V., Krishnan, A., et al. (2023) 'T cell receptor repertoires associated with control and disease progression following Mycobacterium tuberculosis infection'. Nature Medicine, 29 (1). pp. 258 - 269. ISSN: 1078-8956 Open Access Link
Meier, S., Seddon, JA., Maasdorp, E., Kleynhans, L., du Plessis, N., Loxton, AG., et al. (2022) 'Neutrophil degranulation, NETosis and platelet degranulation pathway genes are co-induced in whole blood up to six months before tuberculosis diagnosis'. PLoS ONE, 17 (12). pp. 1 - 24. ISSN: 1932-6203 Open Access Link
Bitencourt, J., Peralta-Álvarez, MP., Wilkie, M., Jacobs, A., Wright, D., Salman Almujri, S., et al. (2022) 'Induction of Functional Specific Antibodies, IgG-Secreting Plasmablasts and Memory B Cells Following BCG Vaccination'. Frontiers in Immunology, 12. pp. 1 - 1. ISSN: 1664-3224 Open Access Link
Kimuda, SG., Andia-Biraro, I., Sebina, I., Egesa, M., Nalwoga, A., Smith, SG., et al. (2020) 'Mycobacterium tuberculosis infection is associated with increased B cell responses to unrelated pathogens'. Scientific Reports, 10 (1). pp. 1 - 11. ISSN: 2045-2322 Open Access Link