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Organ-on-a-chip models for ovarian cancer

Ovarian cancer is a lethal gynaecological malignancy that affects over 295,000 women globally, with a 20% survival rate for advanced stage. Often diagnosed at a late stage, due to the non-specific nature of symptoms, detection of ovarian cancer at an early stage is paramount. The discovery of novel hormones and influencers of the tumour microenvironment provide a promising avenue of research for the identification of cancer biomarkers. This project aims to expand research of a novel glucogenic hormone within the tumour microenvironment using traditional mono-layer tissue culture techniques as well as 3D co-culture organ-on-a-chip technology in addition to clinical liquid biopsies in order to advance the molecular understanding of ovarian cancer aetiology.


Meet the Principal Investigator(s) for the project


Related Research Group(s)

microscope

Organ-on-a-Chip - The group’s main research focus is on women’s health and developing four main organ-on-a-chip (OOC) models: the breast, vagina, ovary, and placenta.


Partnering with confidence

Organisations interested in our research can partner with us with confidence backed by an external and independent benchmark: The Knowledge Exchange Framework. Read more.


Project last modified 21/04/2021