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Case studies of impact from the Centre for Inflammation Research and Translational Medicine (CIRTM) - Coming soon!

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2021

1.      Agostinis, C., Balduit, A., Mangogna, A., Zito, G., Romano, F., Ricci, G., et al. (2021) ‘Immunological Basis of the Endometriosis: The Complement System as a Potential Therapeutic Target’. Frontiers in Immunology, 11. pp. 599117. ISSN: 1664-3224

2.     Agostinis, C., Zorzet, S., Balduit, A., Zito, G., Mangogna, A., Macor, P., et al. (2021) ‘The inflammatory Feed-Forward Loop Triggered by the Complement Component C3 as a Potential Target in Endometriosis’. Frontiers in immunology, 12. ISSN: 1664-3224

3.     Ansari, J., Gavins, F.,(2021) ‘The Impact of Thrombo-inflammation on the Cerebral Microcirculation. Microcirculation.’ Microcirculation., 10 (15). pp.6599 - 6614. ISSN:1838-7640

4.     Ansari, J., Senchenkova, EY., Vital, SA., Al-Yafeai, Z., Kaur, G., Sparkenbaugh EM., et al.(2021) ‘Targeting the AnA1/Fpr2/ALX pathway regulates neutrophil function, promoting thromboinflammation resolution in sickle cell disease.’ Blood., 137 (13). pp.1538 - 1549. ISSN: 0006-4971

5.     Awoyemi, T., Motta-Mejia, C., Zhang, W., Kouser, L., White, K., Kandzija, N., et al. (2021) ‘Syncytiotrophoblast Extracellular Vesicles From Late-Onset Preeclampsia Placentae Suppress Pro-Inflammatory Immune Response in THP-1 Macrophages’. Frontiers in immunology, 12. pp. 676056. ISSN: 1664-3224

6.     Bazban-Shotorbani, S.,  Gavins, F., Kant, K., Dufva, M., Kamaly, N., (2021) ‘A biomicrofluidic screening platform for dysfunctional endothelium targeted nanoparticles and therapeutics.’ BioRXiv. May 2021, doi: https://doi.org/10.1101/2021.05.09.443301.

7.     Boltersdorf, T., Gavins, F., Long, NJ., (2021) ‘Long-lived lanthanide emission via a pH-sensitive and switchable LRET complex’. Chemical Science., 12 (25). pp. 8740 - 8745. ISSN: 2041-6520

8.     Cicirò, Y., Sala, A., (2021) ‘MYB oncoproteins: emerging players and potential therapeutic targets in human cancer’. Oncogenesis, 10 (2). pp. 19. ISSN: 2157-9024

9.     Evangelou, E., Suzuki, H., Bai, W., Pazoki, R., Goa, H., Matthews, PM., et al. (2021) ‘Alcohol consumption in the general population is associated with structural changes in multiple organ systems’. eLife, 10. ISSN: 2050-084X

10.  Ferluga, J., Singh, I., Rout, S., Al-Qahtani, A., Yasmin, H., Kishore, U., (2021) ‘Immune Responses in Malaria and Vaccine Strategies’. Advances in experimental medicine and biology, 1313. pp. 273-291. ISSN: 0065-2598

11.  Ferluga, J., Yasmin, H., Bhakta, S., Kishore, U., (2021) ‘Vaccination Strategies Against Mycobacterium tuberculosis: BCG and Beyond’. Advances in experimental medicine and biology, 1313. pp. 217 - 240. ISSN:0065-2598

12.  Ganguly, K., Kishore, U., Madan, T., (2021) ‘ Interplay between C-type lectin receptors and microRNAs in cellular homeostasis and immune response’. The FEBS journal, 288 (14). pp. 4210 - 4229. ISSN: 1742-464X

13.  Houlden, A.,and MacKay, R., (2021), ‘Can microfluidics be used to create a more realistic in vitro model of the vaginal ectocervix to better understand bacterial vaginosis?’ Sexually Transmitted Infections, ISSN: 1368-4973

14.  Hsieh, MH., Beirag, N., Murugaiah, V., Chou, YC., Kuo, WS., Koa, HF., et al. (2021) ‘Human Surfactant Protein D Binds Spike Protein and Acts as an Entry Inhibitor of SARS-CoV-2 Pseudotyped Viral Particles’. Frontiers in immunology, 12. pp. 641360. ISSN: 1664-3224

15.  Iffah, R., Gavins, F., (2021) ‘Thromboinflammation in coronavirus disease 2019: The Clot Thickens’. Br J British Journal of pharmacology., ISSN: 0007-1188

16.  Jagatia, H., Tsolaki, AG., (2021) ‘ The role of complement system and the immune response to tuberculosis infection’ Medicina, 57 (2). pp. 1 - 18. ISSN: 1010-660X, 1648-9144

17.  Katopodis, P., Anikin, V., Kishore, U., Carter, T., Hall, M., Asadi, N., et al. (2021) ‘ Circulating tumour cells and circulating cell-free DNA in patients with lung cancer: a comparison between thoracotomy and video-assisted thoracoscopic surgery’. BMJ open respiratory research, 8 (1). pp. e000917. ISSN: 2052-4439

18.  Khan, HA., Kishore, U., Alsulami, HM., Alrokayan, SH., (2021) ‘Pro-apoptotic and immunotherapeutic effects of carbon nanotubes functionalized with recombinant human surfactant protein d on leukemic cells’. International journal of molecular sciences, 22 (19). pp. 10445. ISSN: 1661-6596, 1422-0067

19.  Kishore, U., (2021) ‘Preface’. Advances in experimental medicine and biology, 1313. pp. ix- x. ISSN: 0065-2598

20.  Madan, T., Biswas, B., Varghese, M., Subedi, R., Pandit, H., Idicula-Thomas, S., et al. (2021) ‘A Recombinant Fragment of Human Surfactant Protein D Binds Spike Protein and Inhibits Infectivity and Replication of SARS-CoV-2 in Clinical Samples’. American journal of respiratory cell and molecular biology, 65 (1). pp. 41-53. ISSN: 1044-1549

21.  Mangogna, A., Varghese, PM., Agostinis, C., Alrokayan, SH., Khan, HA., Stover, CM., (2021) ‘Prognostic Value of Complement Properdin in Cancer’. Frontiers in immunology, 11. pp. 614980. ISSN: 1664-3224

22.  Marmon, P., Owen, SF., Margiotta-Casaluci, L., (2021) ‘Pharmacology-informed prediction of the risk posed to fish by mixtures of non-steroidal anti-inflammatory drugs (NSAIDs) in the environment’. Environment international, 146. pp. 106222 ISSN: 0160-41202020

23.  Maslova, E., Eisaiankhongi, L., Sjöberg, F.,  McCarthy RR., (2021) ‘Burns and biofilms: priority pathogens and in vivo models’. NPJ biofilms and microbiomes, 7 (1). pp. 73. ISSN: 2055-5008

24.  Mawa, PA., Hasso-Agopsowicz, M., Lubyayi, L., Nabakooza, G., Nakibuule, M., Blitz, R., et al. (2021) ‘Immune Responses Following BCG Immunization of Infants in Uganda and United Kingdom Are Similar for Purified Protein Derivative but Differ for Secretory Proteins’ Frontiers in Immunology, 12. pp. 637114. ISSN: 1664-3224

25.  McCarthy, RR., Larrouy-Maumus, GJ., Meiqi Tan, MGC., Wareham, DW., (2021) ‘Antibiotic Resistance Mechanisms and Their Transmission in Acinetobacter baumannii’. Advances in experimental medicine and biology, 1313. pp. 135 -153. ISSN: 0065-2598

26.  McCleary, S., McCarthy, RR., Strong, R., Edwards, J., Crooke, H., (2021) ‘Inactivation of African Swine Fever Virus by reagents commonly used in containment laboratories’. Journal of virological methods, 295. pp. 114203. ISSN: 0166-0934

27.  Murugaiah, V., Yasmin, H., Pandit, H., Ganguly, K., Subedi, R., Al-Mozaini, M., et al. (2021) ‘Innate Immune Response Against HIV-1’. Advances in experimental medicine and biology, 1313. pp. 23- 58. ISSN: 0065-2598

28.  Pazoki, R., Lin, BD., van Eijk, KR., Schijven, D., de Zwarte, S., Guloksuz, S., et al. (2021) ‘Phenome-wide and genome-wide analyses of quality of life in schizophrenia (vol 7, e13, 2021)’. BJPsych open, 7 (2). pp. 1. ISSN: 2056-4724, 2056-4724

29.  Pazoki, R., Vujkovic, M., Elliott, J., Evangelou, E., Gill, D., Ghanbari, M., et al. (2021) ‘Genetic analysis in European ancestry individuals identifies 517 loci associated with liver enzymes’. Nature communications, 12 (1). ISSN: 2041-1723, 2041-1723

30.  Rehman, S., Ravinayagam, V., Nahvi, I., Aldossary, H., Al-Shammari, M., Amiri, MSA., et al. (2021) ‘Immunity, Sex Hormones, and Environmental Factors as Determinants of COVID-19 Disparity in Women’. Frontiers in immunology, 12. pp. 680845. ISSN: 1664-3224

31.  Remmington, A., Haywood, S., Edgar, J., Green, LR., de Silva, T., Turner, CE., (2021) ‘Cryptic prophages within a streptococcus pyogenes genotype EMM4 lineage’. Microbial genomics, 7 (1). pp. 1 - 14. ISSN: 2057-5858

32.  Roa-Díaz, ZM., Asllanaj, E., Amin, HA., Rojas, LZ., Nano, J., Ikram, MA., et al. (2021) ‘Age at natural menopause and blood pressure traits: Mendelian randomization study’. Journal of clinical medicine,  10 (19). pp. 4299. ISSN: 2077-0383

33.  Sánchez-Cordón, PJ., Floyd, T., Hicks, D., Crooke, HR., McCleary, S., McCarthy, RR., et al. (2021) ‘Evaluation of Lesions and Viral Antigen Distribution in Domestic Pigs Inoculated Intranasally with African Swine Fever Virus Ken05/Tk1 (Genotype X)’. Pathogens (Basel), 10 (6). pp. 768. ISSN: 2076-0817

34.  Tagalakis, AD., Jayarajan, V., Maeshima, R., Ho, KH., Syed, F., Wu, L., et al. (2021) ‘Integrin- Targeted, Short Interfering RNA Nanocomplexes for Neuroblastoma Tumor- Specific Delivery Achieve MYCN Silencing with Improved Survival’. Advanced functional materials, 31(37). pp. 2104843 - n/a. ISSN: 1616-301X

35.  Tan, LKK., Reglinski, M., Teo, D., Reza, N., Lamb, LEM., Nageshwaran, V., et al. (2021) ‘Vaccine-induce, but not natural immunity, against the Streptococcal inhibitor of complement protects against invasive disease’. Npj vaccines, 6 (1). pp. 62. ISSN: 2059-0105

36.  Tsolaki, AG., Varghese, PM., Kishore, U., (2021) ‘Innate Immune Pattern Recognition Receptors of Mycobacterium tuberculosis: Nature and Consequences for Pathogenesis of Tuberculosis’ Advances in experimental medicine and biology, 1313. pp. 179 - 215. ISSN: 0065-2598

37.  Ullah, MW., Rojas, OJ., McCarthy, RR., Yang, G., (2021) ‘Editorial: Nanocellulose: A Multipurpose Advanced Functional Material’. Frontiers in bioengineering and biotechnology, 9. pp. 738779. ISSN: 2296-4185

38.  Varghese, PM., Murugaiah, V., Beirag, N., Temperton, N., Khan, HA., Alrokayan, SH., et al, (2021) ‘C4b Binding Protein Acts as an Innate Immune Effector Against Influenza A Virus’. Frontiers in immunology, 11. pp. 585361. ISSN: 1664-3224

39.  Yasmin, H., Saha, S., Butt, MT., Modi, RK., George, AJT., Kishore, U., (2021) ‘SARS-CoV-2: Pathogenic Mechanisms and Host Immune Response’. Advances in experimental medicine and biology, 1313. pp. 99 - 134. ISSN: 0065-2598

40.  Yasmin, H., Varghese, PM., Bhakta, S., Kishore, U., (2021) ‘ Pathogenesis and Host Immune Response in Leprosy’. Advances in experimental medicine and biology, 1313. pp. 155-177. ISSN: 0065-2598

2020

1.     Andersson, MK., Mangiapane, G., Nevado, PJ., Tsakaneli, A., Carlsson, T., Corda, G., et al. (2020) ‘ATR is a MYB regulated gene and potential therapeutic target in adenoid cystic carcinoma’. Oncogenesis, 9 (1) pp. 5. ISSN: 2157-9024

2.      Bibbo’, S., Lamolinara, A., Capone, E., Purgato, S., Tsakaneli, A., Panella, V., et al. (2020) ‘Repurposing a psychoactive drug for children with cancer: p27Kip1- dependent inhibition of metastatic neuroblastomas by Prozac’. Oncogenesis, 9 (1) pp. 3. ISSN: 2157-9024

3.      Boltersdorf, T., Ansari, J., Senchenkova, EY., Groeper, J., Pajonczyk, D., Vital, SA., et al. (2020) ‘Targeting of Formyl Peptide Receptor 2 for in vivo imaging of acute vascular inflammation’ Theranostics, 10 (15). pp. 6599 - 6614. ISSN: 0006-4971

4.      Brooks, BW., Sabo-Attwood, T., Choi, K., Kim, S., Kostal, J., LaLone, CA., et al. (2020) ‘Toxicology Advances for 21st Century Chemical Pollution’. One earth (Cambridge, Mass.), 2 (4). pp. 312- 316. ISSN: 2590-3330

5.      Capone, E., Lamolinara, A., Pastorino, F., Gentile, R., Ponziani, S., Di Vittorio, G., et al. (2020) ‘Targeting vesicular lgals3bp by an antibody- drug conjugate as novel therapeutic strategy for neuroblastoma’. Cancers, 12 (10). pp. 1 - 18. ISSN: 2072-6694

6.      DeCordova, S., Shastri, A., Tsolaki, AG., Yasmin, H., Klein, L., Singh, S., et al. (2020) ‘Molecular Heterogeneity and Immunosuppressive Microenvironment in Glioblastoma’ Frontiers in immunology, 11. pp. 1402. ISSN: 1664-3224

7.      Ellis, T., Margiotta-Casaluci, L., Pottinger, TG., Morris, S., Reese, RA., Sumpter, JP., et al. (2020) ‘Immunoassays are not immune to errors: Examples from two studies of steroid output from freshwater trout farms’. General and comparative endocrinology, 285. pp. 113226. ISSN: 0016-6480

8.      Elliott, P., Muller, DC., Schneider-Luftman, D., Pazoki, R., Evangelou, E., Dehghan, A., et al. (2020) ‘Estimated 24-Hour Urinary Sodium Excretion and Incident Cardiovascular Disease and Mortality Among 398 628 Individuals in UK Biobank’. Hypertension (Dallas, Tex. 1979), 76 (3). pp. 683-691. ISSN: 0194-911X

9.      Ferluga, J., Yasmin, H., Al-Ahdal, MN, Bhakta, S., Kishore, U., (2020) ‘Natural and trained innate immunity against Mycobacterium tuberculosis’. Immunobiology, 225 (3). pp. 151951. ISSN: 0171-2985

10.  Gomez, I., Ward, B., Souilhol, C., Recarti, C., Ariaans, M., Johnston, J., et al. (2020) ‘Neutrophil microvesicles drive atherosclerosis by delivering miR-155 to atheroprone endothelium’ Nature communications, 11 (1). pp. 214. ISSN: 2041-1723

11.  Huerta Buitrago, B., Margiotta-Casaluci, L., Rodríguez Mozaz, S., Scholze, M., Winter, MJ., Barceló i Cullerés, D., et al. (2020) ‘Anti-anxiety drug and fish behavior: establishing the link between internal concentrations of oxazepam and behavioral effects’. Environmental toxicology and chemistry, ISSN: 0730-7268, 1552-8618

12.  Kale, K., Vishwekar, P., Balsarkar, G., Jassawalla, MJ., Alkahtani, S., Kishore, U., (2020) ‘Serum Levels of Collectins Are Sustained During Pregnancy: Surfactant Protein D Levels Are Dysregulated Prior to Missed Abortion’. Reproductive sciences, 27 (10). pp. 1894 - 1908. ISSN: 1933-7191

13.  Kishore, U., Bulla, R., Madan, T., (2020) ‘Editorial: Odyssey of Surfactant Proteins SP-A and SP-D: Innate Immune Surveillance Molecules’. Frontiers in immunology, 11. pp. 394. ISSN: 1664-3224

14.  Kishore, U., Ghebrehiwet, B., (2020) ‘C1q: A molecular bridge to innate and adaptive immunity’. ISSN: 1664-3224, 1664-3224

15.  Legler, J., Zalko, D., Jourdan, F., Jacobs, M., Fromenty, B., Balaguer, P., et al. (2020) ‘The GOLIATH Project: Towards an Internationally Harmonised Approach for Testing Metabolism Disrupting Compounds’. International journal of molecular sciences, 21 (10). pp. 3480. ISSN: 1661-6596, 1422-0067

16.  Lubyayi, L., Mawa, PA., Nabakooza, G., Nakibuule, M., Tushabe, JV., Serubanja, J., et al. (2020) ‘Maternal Latent Mycobacterium tuberculosis Does Not Affect the Infant Immune Response Following BCG at Birth: An Observational Longitudinal Study in Uganda’. Frontiers in immunology, 11. pp. 929. ISSN: 1664-3224

17.  Madan, T., Kishore, U., (2020) ‘Surfactant Protein D Recognises Multiple Fungal Ligands: A Key Step to Initiate and Intensify the Anti-fungal Host Defense’. Frontiers in cellular and infection microbiology, 10. pp. 229. ISSN: 2235-2988

18.  Mahony, C., Ashton, RS., Birk, B., Boobis, AR., Cull, T., Daston, GP., et. al. (2020) ‘New ideas for non-animal approaches to predict repeated- dose systemic toxicity: Report from an EPAA Blue Sky Workshop’. Regulatory toxicology and pharmacology, 114. ISSN: 0273-2300, 1096-0295

19.  Maslova, E., Shi, Y., Sjöberg, F., Azevedo, HS., Wareham, DW., McCarthy, RR., (2020) ‘An Invertebrate Burn Wound Model That Recapitulates the Hallmarks of Burn Trauma and Infection Seen in Mammalian Models’. Frontiers in microbiology, 11. pp. 998. ISSN: 1664-302X

20.  McCleary, S., Strong, R., McCarthy, RR., Edwards, JC., Howes, EL., Stevens, LM., et al. (2020) ‘Substitution of warthog NF-kB motifs into RELA of domestic pigs is not sufficient to confer resilience to African swine fever virus’. Scientific reports, 10 (1). pp. 8951. ISSN: 2045-2322

21.  Moses, RL., Dally, J., Lundy, FT., Langat, M., Kiapranis, R., Tsolaki, AG., et al. (2020) ‘Lepiniopsis ternatensis  sap stimulates fibroblast proliferation and down regulates macrophage TNF-⍺ secretion’ Fitoterapia, 141. pp. 104478. ISSN: 0367-326X

22.  Murugaiah, V., Agostinis, C., Varghese, PM., Belmonte, B., Vieni, S., Alaql, FA., et al. (2020) ‘Hyaluronic Acid Present in the Tumor Microenvironment Can Negate the Pro-apototic Effect of a Recombinant Fragment of Human Surfactant Protein D on Breast Cancer Cells’. Frontiers in Immunology, 11. pp. 1171. ISSN: 1664-3224

23.  Murugaiah, V., Tsolaki, AG., Kishore, U., (2020). ‘Collectins: Innate Immune Pattern Recognition Molecules’ Advances in experimental medicine and biology, 1204. pp. 75 -  127. ISSN: 0065-2598

24.  Murugaiah, V., Varghese, PM., Saleh, SM., Tsolaki, AG., Alrokayan, SH., Khan, HA., et al. (2020) ‘Complement- Independent Modulation of Influenza A Virus Infection by Factor H’. Frontiers in immunology, 11. pp. 355. ISSN: 1664-3224

25.  Omura, S., Sato, F., Park, A., Fujita, M., Nishio, K., Gavins, F., Tsunoda, I., (2020) ‘Bioinformatics Analysis of Gut Microbiota and CNS Transcriptome in Virus-Induced Acute Myelitis and Chronic Inflammatory Demyelination; Potential Association of Distinct Bacteria with CNS IgA upregulation. Frontiers in Immunology, section Mucosal Immunity.’ Frontiers in Immunology., 11. pp. 1138. ISSN: 1664-3224

26.  Pazoki, R., Lin, BD., van Eijk, KR., Schijven, D., de Zwarte, S., Guloksuz, S., et al. (2020) ‘Phenome-wide and genome-wide analyses of quality of life in schizophrenia’. BJPsych open, 7 (1). pp. e13. ISSN: 2056-4724

27.  Pérez-Hernández, CA., Kern, CC., Butkeviciute, E., McCarthy, E., Dockrell, HM., Moreno-Altamirano, MMB., et al. (2020) ‘Mitochondrial Signature in Human Monocytes and Resistance to Infection in C. elegans During Fumarate-Induced Innate Immune Training’. Frontiers in immunology, 11.  pp. 1715. ISSN: 1664-3224

28.  Riaz, MS., Kaur, A., Shwayat, SN., Behboudi, S., Kishore, U., Pathan, AA., (2020) ‘Dissecting the Mechanism of IntracellularMycobacterium smegmatisGrowth Inhibition by Platelet Activating Factor C-16’. Frontiers in microbiology, 11. pp. 14. ISSN: 1664-302X, 1664-302X

29.  Rivetti, C., Allen, TEH., Brown, JB., Butler, E., Carmichael PL., Colbourne, JK., et al (2020) ‘Vision of a near future: Bridging the human health-environment divide. Toward an integrated strategy to understand mechanisms across species for chemical safety assessment’. Toxicology in vitro, 62. pp. 1-9. ISSN: 0887-2333

30.  Robinson, O.,  Chadeau Hyam, M., Karaman, I., Climaco Pinto, R., Ala-Korpela, M., Handakas, E., et al. (2020) ‘Determinants of accelerated metabolomic and epigenetic ageing in a UK cohort’. Aging cell, 19 (6). pp. e13149 - n/a. ISSN: 1474-9718

31.  Siggins, MK., Lynskey, NN., Lamb, LE., Johnson, LA., Huse, KK., Pearson, M., et al. (2020) ‘Extracellular bacterial lymphatic metastasis drives Streptococcus pyogenes systemic infection’. Nature communications, 11 (1). pp. 4697. ISSN: 2041-1723

32.  Symonds, ALJ., Zheng, W., Miao, T., Wang, H., Wang, T., Kiome, R., et al. (2020) ‘Egr2 and 3 control inflammation, but maintain homeostasis, of PD-1 high memory phenotype CD4 T cells’. Life science alliance, 3 (9). pp. e202000766. ISSN: 2575-1077

33.  Thakur, G., Sathe, G., Kundu, I., Biswas, B., Gautam, P., Alkahtani, S., et al. (2021) ‘Membrane Interactome of a Recombinant Fragment of Human Surfactant Protein D Reveals GRP78 as a Novel Binding Partner in PC3, a Metastatic Prostate Cancer Cell Line’. Frontiers in immunology, 11. pp. 600660. ISSN: 1664-3224

34.  Thompson, WD., Beaumont, RN., Kuang, A., Warrington, NM., Ji, Y., Tyrrell, J., et al., (2021) ‘Higher maternal adiposity reduces offspring birthweight if associated with a metabolically favourable profile’ Diabetologia, 64 (12). pp. 2790 - 2802. ISSN: 0012-186X

35.  Varghese, PM., Tsolaki, AG., Yasmin, H., Shastri, Abhishek., Ferluga, J., Vatish, M., et al. (2020) ‘Host- pathogen interaction in COVID-19: Pathogenesis, potential therapeutics and vaccination strategies’ Immunobiology, 225(6). pp. 152008. ISSN: 0171-2985

36.  Vital, SA., Senchenkova, EY., Ansari, J., Gavins, F., (2020) 'Targeting AnxA1/Formyl Peptide Receptor 2 Pathway Affords Protection against Pathological Thrombo-Inflammation.’ Cells., 9 (11). pp. 1. ISSN: 2073-4409

37.  Võsa, U., Claringbould, A., Westra, HJ., Bonder, MJ., Deelen, P., Zeng, B., et al., (2021) ‘Large-scale cis- and trans-eQTL analyses identify thousands of genetic loci and polygenic scores that regulate blood gene expression’ Nature genetics, 53 (9).pp.1300 - 1310. ISSN: 1061-4036, 1546-1718

2019

1.      Agostinis, C., Mangogna, A., Bossi, F., Ricci, G., Kishore, U., Bulla, R., (2019) ‘Uterine Immunity and microbiota: A shifting paradigm’. Frontiers in immunology, 10. pp. 2387. ISSN: 1664-3224

2.     Agostinis, C., Masat, E., Bossi, F., Ricci, G., Menegazzi, R., Lombardelli, L., et al. (2019) ‘Transcriptomics and Immunological Analyses Reveal a Pro-angiogenic and Anti-inflammatory Phenotype for Decidual Endothelial Cells’. International Journal of molecular sciences, 20 (7). pp. 1604. ISSN: 1661-6596, 1422-0067

3.      Al-Qahtani, AA., Murugaiah, V., Bashir, HA., Pathan, AA., Abozaid, SM., Makarov, E., et al. (2019) ‘Full length human surfactant protein A inhibits influenza A virus infection of A549 lung epithelial cells: A recombinant form containing neck and lectin domains promotes infectivity’. Immunobiology (1979), 224 (3). pp. 408-418. ISSN: 0171-2985

4.     Ansari, J., Gavins, F.,(2019) ‘Ischemia-Reperfusion Injury in Sickle Cell Disease: From Basics to Therapeutics.’ The American journal of pathology, 189 (4). pp. 706 - 718. ISSN:0002-9440

5.     Armitage, EP., Senghore, E., Darboe, S., Barry, M., Camara, J., Bah, S., et al. (2019) ‘High burden and seasonal variation of paediatric scabies and pyoderma prevalence in the Gambia: A cross-sectional study’. PLoS neglected tropical diseases, 13 (10). pp. e0007801. ISSN: 1935-2727, 1935-2735

6.     Barzegar, M., Kaur, G., Gavins, F., Wang, Y., Boyer, CJ., Alexander, JS., (2019) ‘Potential therapeutic roles of stem cells in ischemia-reperfusion injury’. International journal of molecular sciences, 19 (4). pp. 1211. ISSN: 1661-6596, 1422-0067

7.     Becker, F.*, Gavins, F.*, Fontenot, J., Jordan, P., Yun, JY., Scott, R., et al. (2019) ‘Dynamic gut microbiome changes following regional intestinal lymphatic obstruction in primates.’ Pathophysiology. 2019;26:253-261. (*Authors contributed equally.)

8.     Becker, F., Romero, E., Goetzmann, J., Hasselschwert, DL., Dray, B., Vanchiere, J., et al. (2019) 'Endogenous Specialized Proresolving Mediator Profiles in a Novel Experimental Model of Lymphatic Obstruction and Intestinal Inflammation in African Green Monkeys.’ The American journal of pathology, 189 (10). pp. 1953 - 1972. ISSN: 0002-9440

9.     Boltersdorf, T., Ansari, J., Senchenkova, EY., Jiang, L., White, AJP., Coogan, M.,et al. (2019) 'Development, characterisation, and in vitro evaluation of lanthanide-based FPR2/ALX-targeted imaging probes.' Dalton transactions : an international journal of inorganic chemistry, 48 (44). pp. 16764 - 16775. ISSN: 1477-9226

10.  Booth, P., McCarthy, R., (2019) ‘Developing high through put screening strategies to identify the next generation of antimicrobials’.  Access microbiology, 1 (10). ISSN: 2516-8290, 2516-8290

11.  DeCordova, S., Abdelgany, A., Murugaiah, V., Pathan, AA., Nayak, A., Walker, T., et al. (2019) ‘Secretion of functionally active complement factor H related protein 5 (FHR5) by primary tumour cells derived from Glioblastoma Multiforme patients’. Immunobiology (1979), 224 (5). pp. 625 - 631. ISSN: 0171-2985

12.  de Vries, PS., Brown, MR., Bentley, AR., Sung, YJ., Winkler, TW.,  Ntalla, I.,  et al. (2019) ‘Multiancestry Genome-Wide Association Study of Lipid Levels Incorporating Gene-Alcohol Interactions’. American journal of epidemiology, 188 (6). pp. 1033 - 1054. ISSN: 0002-9262, 1476-6256

13.  Evangelou, E., Gao, H., Chu, C., Ntritsos, G., Blakeley, P., Butts, AR., et al. (2019) ‘New alcohol-related genes suggest shared genetic mechanisms with neuropsychiatric disorders’. Nature human behaviour, 3 (9). pp. 950-961. ISSN: 2397-3374, 2397-3374

14.  Guitérrez-Barranquero, JA., Reen, FJ., Parages, ML., McCarthy, R., Dobson, ADW., O’Gara, F., (2019) ‘Disruption of N-acyl-homoserine lactone-specific signalling and virulence in clinical pathogens by marine sponge bacteria’. Microbial biotechnology, 12 (5) pp. 1049 -  1063. ISSN: 1751-7915, 1751-7907

15.  Gunnarsson, L., Snape, JR., Verbruggen, B., Owen, SF., Kristiansson, E., Margiotta-Casaluci, L., et al. (2019) ‘Pharmacology beyond the patient - The environmental risks of human drugs’. Environment international, 129. pp. 320- 332. ISSN: 0160-4120

16.  Harris, SE., Hagenaars, SP., Ritchie, SJ., Marioni, RE., Fawns-Ritchie, C., Liewald, DCM., et al. (2019) ‘Author Correction: Study of 300,486 individuals identifies 148 independent genetic loci influencing general cognitive function’. Nature communications, 10 (1). pp. 2068. ISSN: 2041-1723

17.  Kumar, J., Murugaiah, V., Sotiriadis, G., Kaur, A., Jeyaneethi, J., Stumiolo, L., et al. (2019) ‘Surfactant Protein D as a Potential Biomarker and Therapeutic Target in Ovarian Cancer’. Frontiers in oncology, 9. pp. 542. ISSN: 2234-943X

18.  Lee, H., Kim, J., Kang, YA., Kim, DR., Sim, B., Zelmer, A., et al. (2019) ‘In vitro Mycobacterial Growth Inhibition in South Korean Adults With Latent TB Infection’. Frontiers in immunology, 10. pp. 896. ISSN: 1664-3224

19.  Lynskey, NN., Jauneikaite, E., Li, HK., Zhi, X., Turner, CE., Mosavie, M., et al. (2019) ‘Emergence of dominant toxigenic M1T1 Streptococcus pyogenes clone during increased scarlet fever activity in England: a population-based molecular epidemiological study’. The Lancet infectious diseases, 19 (11). pp. 1209 - 1218. ISSN: 1473-3099

20.  Luykx, J., Pazoki, R., Lin, B., Guloksuz, S., Schijven, D., van Eijk, K., et al. (2019) ‘T168. Phenome-Wide and Genome-Wide Analyses of Quality of  Life in Patients with Psychosis’. Biological psychiatry (1969),  85 (10) pp. S194. ISSN: 0006-3223

21.  Mangogna, A., Agostinis, C., Bonazza, D., Belmonte, B., Zacchi, P., Zito, G., et al. (2019) ‘Is The Complement Protein C1q a Pro-  or Anti- tumorigenic Factor? Bioinformatics Analysis Involving Human Carcinomas’. Frontiers in immunology, 10 (MAY). pp. 865. ISSN: 1664-3224

22.  Mangogna, A., Belmonte, B., Agostinis, C., Zacchi, P., Iacopino, DG., Martorana, A., et al. (2019) ‘Prognostic Implications of the Complement Protein C1q in Gliomas’. Frontiers in immunology, 10. pp. 2366. ISSN: 1664-3224

23.  Margiotta-Casaluci, L., Dusza, H., Moreira, I., Winter, MJ., Prior, H., (2019) ‘Development of an adverse outcome pathway (AOP) for cardiotoxicity mediated by the blockade of L-type calcium channels’. Journal of pharmacological and toxicological methods, 99. pp. 106595. ISSN: 1056-8719

24.  Margiotta-Casaluci, L., Owen, SF., Rand-Weaver, M., Winter, MJ., (2019) ‘Testing the Translational Power of the Zebrafish: An Interspecies Analysis of Responses to Cardiovascular Drugs.’ Frontiers in pharmacology, 10. pp. 893. ISSN: 1663-9812

25.  McCarthy R., (2019) ‘ Maximum overdrive: Deegan try is a real Lyon tamer [Eire Region]’. Sun (Plainfield, III.: Homer Township, Lockport, Lemont ed.), ISSN: 0307-2681

26.  McCarthy, RR., Everett, HE., Graham, SP., Steinbach, F., Crooke, HR., (2019) ‘Head Start Immunity: Characterizing the Early Protection of C Strain Vaccine Against Subsequent Classical Swine Fever Virus Infection’. Frontiers in immunology, 10. pp. 1584. ISSN: 1664-3224

27.  McCarthy, RR., Ullah, MW., Booth, P., Pei, E., Yang, G., (2019) ‘The use of bacterial polysaccharides in bioprinting’. Biotechnology advances, 37 (8). pp. 107448. ISSN: 0734-9750

28.  McCarthy, RR., Ullah, MW., Pei, E., Yang, G., (2019) ‘Antimicrobial Inks: The Anti-Infective Applications of Bioprinted Bacterial Polysaccharides’. Trends in biotechnology (Regular ed.), 37 (11). pp. 1155-1159. ISSN: 0167-7799

29.  McCarthy, RR., Yu, M., Eilers, K., Wang, Y., Lai, E., Filloux, A., (2019) ‘Cyclic di-GMP inactivates T6SS and T4SS activity in Agrobacterium tumefaciens’. Molecular microbiology, 112 (2). pp. 632- 648. ISSN: 0950-382X

30.  Nieddu, V., Piredda, R., Bexell, D., Barton, J., Anderson, J., Sebire, N., et al. (2019) ‘Engineered human mesenchymal stem cells for neuroblastoma therapeutics’. Oncology reports, 42 (1) pp. 35 - 42. ISSN: 1021-335X

31.  Pandit, H., Kale, K., Yamamoto, H., Thakur, G., Rokade, S., Chakraborty, P., et al. (2019) ‘Surfactant Protein D Reverses the Gene Signature of Transepithelial HIV-1 Passage and Restricts the Viral Transfer Across the Vaginal Barrier’. Frontiers in immunology, 10. pp. 264. ISSN: 1664-3224

32.  Pazoki, R., (2019) ‘Cardiovascular disease, ABO locus, and markers of platelet functionality’. International journal of cardiology, 286. pp. 162-163. ISSN: 0167-5273

33.  Pazoki, R., Dehghan, A., Evangelou, E., Warren, H., Gao, H., Caulfield, M., et al. (2019) ‘Genetic Predisposition to High Blood Pressure and Lifestyle Factors: Associations With Midlife Blood Pressure Levels and Cardiovascular Events’. Circulation, 139 (2). pp. E2. ISSN: 0009-7322

34.  Pazoki, R., Evangelou, E., Mosen-Ansorena, D., Pinto, RC., Karaman, I., Blakeley, P., et al. (2019) ‘GWAS for urinary sodium and potassium excretion highlights pathways shared with cardiovascular traits’. Nature communication, 10 (1). pp. 3653 - 11. ISSN: 2041-1723

35.  Prabowo, SA., Painter, H., Zelmer, A., Smith, SG., Seifert, K., Amat, M., et al. (2019) ‘Fletcher HA. RUTI Vaccination Enhances Inhibition of Mycobacterial Growth ex vivo and Induces a Shift of Monocyte Phenotype in Mice’. Frontiers in immunology, 10. pp. 894. ISSN: 1664-3224

36.  Prabowo, SA., Smith, SG., Seifert, K., Fletcher, HA., (2019) ‘Impact of individual-level factors on Ex vivo mycobacterial growth inhibition: Associations of immune cell phenotype, cytomegalovirus-specific response and sex with immunity following BCG vaccination in humans’. Tuberculosis, 119. pp. 101876. ISSN: 1472-9792

37.  Prabowo, SA., Zelmer, A., Stockdale, L., Ojha, U., Smith, SG., Seifert, K., et al. (2019) ‘Historical BCG vaccination combined with drug treatment enhances inhibition of mycobacterial growth ex vivo in human peripheral blood cells’. Scientific reports, 9(1). pp. 4842. ISSN: 2045-2322

38.  Preiss, D., Swerdlow, D., Fatemifar, G., Faraway, R., Finan, C., Fairhurst-Hunter, Z., et al. (2019) ‘Phenome-wide association analysis of LDL-cholesterol lowering genetic variants in PCSK9’. BMC cardiovascular disorders, 19 (1). pp. 240. ISSN: 1471-2261

39.  Rabeeah, I., Kishore, U., Nal-Rogier, B., Shelton, H., (2019) ‘Influenza A Virus interactions with complement factor H’. Access microbiology, 1 (1A). ISSN: 2516-8290, 2516-8290

40.  Reen, FJ., Guitérrez-Barranquero, JA., McCarthy, RR., Woods, DF., Scarciglia, S., Adams, C., et al. (2019) ‘Quorum Sensing Signaling Alters Virulence Potential and Population Dynamics in Complex Microbiome-Host Interactomes’. Frontiers in microbiology, 10. pp. 2131. ISSN: 1664-302X

41.  Reglinski, M., Sriskandan, S., Turner, CE., (2019) ‘Identification of two new core chromosome-encoded superantigens in Streptococcus pyogenes; speQ and speR’. The Journal of infection, 78(5). pp. 358 - 363. ISSN: 0163-4453

42.  Senchenkova, EY., Ansari, J, Becker F., Vital, SA., Al-Yafeai, Z., Sparkenbaugh, EM., et al.  (2019) ‘Novel Role for the AnxA1-Fpr2/ALX Signaling Axis as a Key Regulator of Platelet Function to Promote Resolution of Inflammation.’ Circulation, 140 (4). pp. 319 - 335. ISSN: 0009-7322

43.  Senchenkova, EY., Russell, J., Yildirim, A., Granger, DN., Gavins, F., (2019) ‘Novel Role of T Cells and IL-6 (Interleukin-6) in Angiotensin II-Induced Microvascular Dysfunction. Hypertension.’ Hypertension, 73 (4). pp. 829 - 838. ISSN: 0194-911X

44.  Sharif, H., Singh, I., Kouser, L., Mösges, R., Bonny, MA., Karamani, A., et al. (2019) ‘ Immunologic mechanisms of a short-course of Lolium perenne peptide immunotherapy: A randomized, double-blind, placebo-controlled trial’. Journal of allergy and clinical immunology, 144 (3). pp. 738- 749. ISSN: 0091-6749, 1097-6825

45.  Sharma, H., Turner, CE., Siggins, MK., El-Bahrawy, M., Pichon, B., Kearns, A., et. al. (2019) ‘Toxic Shock Syndrome Toxin 1 Evaluation and Antibiotic Impact in a Transgenic Model of Staphylococcal Soft Tissue Infection’. mSphere, 4 (5). pp. e00665-19. ISSN: 2379-5042

46.  Tanner, R., Smith, SG., Van Meijgaarden, KE., Giannoni, F., Wilkie, M., Gabriele, L., et al. (2019) ‘Optimisation, harmonisation and standardisation of the direct mycobacterial growth inhibition assay using cryopreserved human peripheral blood mononuclear cells’. Jornal of immunological methods, 469. pp. 1 - 10. ISSN: 0022-1759

47.  Tanoue, R., Margiotta-Casaluci, L., Huerta, B., Runnalls, TJ., Eguchi, A., Nomiyama, K., et al. (2019) ‘Protecting the environment from psychoactive drugs: Problems for regulators illustrated by the possible effects of tramadol on fish behaviour’. The Science of the total environment, 664. pp. 915 - 926. ISSN: 0048-9697

48.  Thakur, G., Prakash, G., Murthy, V., Sable, N., Menon, S., Alrokayan, SH., et al. (2019) ‘Human SP-D Acts as an Innate Immune Surveillance Molecule Against Androgen-Responsive and Androgen- Resistant Prostate Cancer Cells’. Frontiers in oncology, 9. pp. 565. ISSN: 2234-943X

49.  Turner, CE., Bubba, L., Efstratiou, A., (2019) ‘Pathogenicity Factors in Group C and G Streptococci’. Microbiology spectrum, 7 (3). pp. 13. ISSN: 2165-0497

Turner, CE., Holden, MTG., Blane, B., Horner, C., Peacock, SJ., Sriskandan, S., (2019) ‘The. Emergence of successful Streptococcus pyogenes lineages through convergent pathways of capsule loss and recombination directing high toxin expression’. mBio, 10 (6). pp. e02521-19. ISSN: 2161-2129, 2150-7511