Dr Byron Creese
Director of Research
Quad North 146
- Email: byron.creese@brunel.ac.uk
- Tel: +44 (0)1895 265623
Summary
Research Summary
I am a translational researcher whose research focuses on neuropsychiatric symptoms in dementia and late-life onset neuropsychiatric symptoms as markers of neurodegenerative disease. My research employs a variety of approaches from psychology to genomics and epidemiology to investigate the disease mechanisms and clinical consequences of these symptoms.
My work draws on extensive experience with large longitudinal datasets, proxy-reported and self-reported outcomes, and complex statistical modelling.
I have published numerous research articles in peer-reviewed journals and presented research at national and international conferences. In addition to my research, I am actively involved in mentoring students and am committed to fostering the next generation of dementia researchers.
I received my PhD from King's College London and completed a postdoctoral research there and at University of Exeter.
Consultancy
I also provide research-led consultancy to MedTech and pharmaceutical organisations, delivered via the University https://www.brunel.ac.uk/business/Research-and-development/Consultancy).
My expertise lies in real-world evidence (RWE), behavioural and cognitive outcomes, and neuropsychiatric symptoms, with a particular focus on ageing, dementia, and mental health. I work with industry teams to generate and interpret evidence that supports product development and clinical strategy.
I support MedTech and Pharma partners with:
- Study design and evidence strategy for observational and longitudinal research
- Advanced analysis of real-world and patient-reported outcomes data
- Interpretation of behavioural, neuropsychiatric, and cognitive endpoints
- Evidence to support value propositions, payer conversations, and regulatory engagemeny
All consultancy is undertaken via Brunel University London.
Qualifications
PhD King's College London
Newest selected publications
Macfarlane, D., Dahir, I., Ali, R., Ghosalkar, N., Webb, LM., Ismail, Z., et al. (2025) 'Acceptability and feasibility of a sensor-instrumented ‘SmartSocks’ wearable prototype to detect agitation in people with dementia'. International Psychogeriatrics, 0 (in press, corrected proof). pp. 1 - 3. ISSN: 1041-6102 Open Access Link
Choma, J., Griffiths, A., Henley, W., Mueller, C., Williams, N., Ballard, C., et al. (2025) 'Risk of stroke associated with risperidone in dementia with and without comorbid cardiovascular disease: population-based matched cohort study'. British Journal of Psychiatry, 0 (ahead of print). pp. 1 - 7. ISSN: 0007-1250 Open Access Link
Namasivayam, AA., Fischer, CE., Abler, V., Creese, B., Gastiazoro, MP., Hermida, AP., et al. (2025) 'Recommendations for management and future investigation of psychosis in neurodegenerative disease: Findings from the International Psychogeriatric Association (IPA) working group'. International Psychogeriatrics, 0 (in press, corrected proof). pp. 1 - 9. ISSN: 1041-6102 Open Access Link
Shwab, EK., Pathak, GA., Harvey, J., Belloy, ME., Fischer, CE., Lutz, MW., et al. (2025) 'Leveraging multiomic approaches to elucidate mechanisms of heterogeneity in Alzheimer's disease: Neuropsychiatric symptoms, co-pathologies, and sex differences'. Alzheimer's and Dementia, 21 (8). pp. 1 - 24. ISSN: 1552-5260 Open Access Link
Malkowski, OS., Harvey, J., Townsend, NP., Kelson, MJ., Foster, CEM., Western, MJ., et al. (2025) 'Correlates and determinants of physical activity among older adults of lower versus higher socio-economic status: a systematic review and meta-analysis'. International Journal of Behavioral Nutrition and Physical Activity, 22 (1). pp. 1 - 16. ISSN: 1479-5868 Open Access Link