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Colleges

Research degrees

Research students are welcomed to Brunel as valued members of our thriving, research-intensive community. Find out more about Research Degrees in Brunel. A research degree provides the opportunity to investigate a topic in depth, and contribute new knowledge to your discipline.

Proposed PhD Projects

Description
Supervisor
Funding
Study of the ageing-related pre-mRNA splicing of the LMNA gene
Precursor messenger RNA (pre-mRNA) splicing is a cellular process in which non-coding sequences (introns) are removed and coding sequences (exons) are joined together to generate mRNA for protein prod...
Evgeny Makarov
Self Funded
Effects on the genome of new treatments for the premature ageing disease Hutchinson-Gilford Progeria Syndrome
HGPS is a premature ageing syndrome that affects children leading to their premature death in their teens through heart attacks and strokes. There have been a few drugs that have been given to the chi...
Self Funded
Nanoparticles in drug delivery
Nanoparticles (NPs) are materials with overall dimensions in the nano scale range (5nm-100nm). Due to their unique physicochemical properties, they have found a wide range of applications and are curr...
Gudrun Stenbeck
Self Funded
The impact of chromosomal rearrangements on the genome organisation of leukaemia cells.
Chromosomal rearrangements are a hallmark of leukaemia. It is well known that specific chromosomal rearrangements are associated with certain leukaemia subtypes and that can predict clinical outcome. ...
Sabrina Tosi
Self Funded
Budding yeast as a model for sudden cardiac death
Sudden unexpected cardiac death is responsible for about half of all heart disease deaths. It is an unexpected death caused by a change in heart rhythm. The underlying mechanisms are still not fully u...
Thomas Hofken
Self Funded
Differential expression patterns and transport characteristics of aged cells
Ageing is associated with a number of diseases and manifests itself at the organ level (e.g. the morphological changes in the skin) as well as cellular level. Cellular function is dependent on correct...
Gudrun Stenbeck
Self Funded
Inducing the reversal of cellular ageing in model cell systems
As normal cells age they can only go through a finite number of cell divisions. Once they have achieved this they become irreversibly growth arrested known as replicative senescence. The transcriptome...
Self Funded
Targeting TERT and the MYCN gene network as a novel therapeutic approach for high-risk neuroblastoma
MYCN belongs to a small family of transcription factors implicated in fundamental cellular processes. There are 3 members of the MYC family in mammalian cells, c-MYC, MYCN and L-MYC. They interact wit...
Arturo Sala
Self Funded
Genetic and non-genetic factors involved in risk of cardiovascular diseases
Main Aim: To identify genetic and non-genetic causes of cardiovascular diseases Cardiovascular diseases including hypertension, myocardial infarction, heart failure, and stroke are the leading causes ...
Raha Pazoki
Self Funded
Ageing-related pre-mRNA splicing of LMNA gene
The aim is to investigate the molecular mechanism of the pre-mRNA splicing event which outcome could then be modulated to slow the ageing process. Precursor messenger RNA (pre-mRNA) splicing is a cell...
Evgeny Makarov
Self Funded

 

Funding for doctoral studies

A number of studentships and other research funding opportunities are available at Brunel. Please see full list here: Research degree funding. 

Choosing your supervisor

Our researchers create knowledge and advance understanding, and equip versatile graduates with the confidence to apply what they have learnt for the benefit of society. Browse the list of the members of our Theme to select your potential supervisor here. You are welcome to approach your potential supervisor directly to discuss your research interests.

All research degrees are administered by the Postgraduate Programmes Office in Colleges. Once you have identified your area of research and a potential supervisor, please use the contact details provided here for enquiries.