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Colleges

PhD topics for research students

Find below a list of currently available self-funded PhD topics.

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Check out fees and funding

We encourage all students to contact the supervisor or the alternative contact person for more information and an informal chat to discuss the process of applying and preparing your research statement. For more information on how to apply click here.

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Description
Supervisor
Funding
Inducing the reversal of cellular ageing in model cell systems
As normal cells age they can only go through a finite number of cell divisions. Once they have achieved this they become irreversibly growth arrested known as replicative senescence. The transcriptome...
Self Funded
Targeting TERT and the MYCN gene network as a novel therapeutic approach for high-risk neuroblastoma
MYCN belongs to a small family of transcription factors implicated in fundamental cellular processes. There are 3 members of the MYC family in mammalian cells, c-MYC, MYCN and L-MYC. They interact wit...
Arturo Sala
Self Funded
Genetic and non-genetic factors involved in risk of cardiovascular diseases
Main Aim: To identify genetic and non-genetic causes of cardiovascular diseases Cardiovascular diseases including hypertension, myocardial infarction, heart failure, and stroke are the leading causes ...
Raha Pazoki
Self Funded
Ageing-related pre-mRNA splicing of LMNA gene
The aim is to investigate the molecular mechanism of the pre-mRNA splicing event which outcome could then be modulated to slow the ageing process. Precursor messenger RNA (pre-mRNA) splicing is a cell...
Evgeny Makarov
Self Funded
Investigating Therapeutic Effect of Different Antioxidants in Friedreich’s Ataxia (FRDA)
Friedreich’s ataxia (FRDA) is an inherited neurodegenerative disorder caused by epigenetic silencing of the frataxin gene. It is the most common inherited ataxia, affecting 1:50,000 Caucasians, and is...
Sara Anjomani Virmouni
Self Funded
Investigating the function of common genetic variants that increase colorectal cancer risk.
Over 1 in 20 people in the UK will be diagnosed with colorectal cancer (CRC) during their lifetime. Much of this risk is genetically inherited with estimates ranging from 12 to 40%. Known cancer syndr...
Annabelle Lewis
Self Funded
Central Nervous system Gene therapy to treat obesity Bardet-Biedl Syndrome (BBS). Analysis of the BBS brain development
Bardet-Biedl syndrome (BBS) is a debilitating, often life-limiting heritable multisystem disorder caused by dysfunction of non-motile cilia (ciliopathy). There is currently no cure for BBS, a disease ...
Victor Hernandez
Self Funded
Individual histone modification roles in regulation of transcription and cell decision-making
We are looking for a highly-motivated, technically-able and independent-thinking candidate to undertake a PhD project exploring the role of individual histone modifications in nuclear organisation, re...
Cristina Correia Antunes Pina
Self Funded
Decision making for stratified medicine life cycle
Stratified medicine is at the cutting edge of a new era in healthcare, which targets to a specific patient population on the basis of a companion diagnostic (such as a biomarker) to predict treatment ...
Yang Yang
Self Funded
Decision making for stratified medicine life cycle
Stratified medicine is at the cutting edge of a new era in healthcare, which targets to a specific patient population on the basis of a companion diagnostic (such as a biomarker) to predict treatment ...
Yang Yang
Self Funded